Interactor 1: PUR6 (Q10457)
Probable multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)]
Gene: pacs-1
Interactor 2: PUR6 (Q10457)
Probable multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)]
Gene: pacs-1
Species: Caenorhabditis elegans
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.53 | 1.00 | 0.733 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 14704431 |
| Identification Methods | two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AIRC~AIRC, AIRC~SAICAR_synt, SAICAR_synt~SAICAR_synt |
| Common GO terms | GO:0004638 - phosphoribosylaminoimidazole carboxylase activity GO:0004639 - phosphoribosylaminoimidazolesuccinocarboxamide synthase activity GO:0005524 - ATP binding GO:0005829 - cytosol GO:0006189 - 'de novo' IMP biosynthetic process and 1 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
