Protein: SRP68
Signal recognition particle subunit SRP68 (SRP68) (Signal recognition particle 68 kDa protein)

Gene: SRP68
Organism: Drosophila melanogaster
Interactions: 161
UniProt ID: Q9VSS2

Gene Ontology (top 5):
GO:0005047 - signal recognition particle binding
GO:0005730 - nucleolus
GO:0005783 - endoplasmic reticulum
GO:0005786 - signal recognition particle, endoplasmic reticulum targeting
GO:0006614 - SRP-dependent cotranslational protein targeting to membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1471688

Q9VDK7
Signal recognition particle subunit SRP72

2

2

High-throughput

0.737

High

1306441

INDRA
Zinc finger protein indra

1

0

High-throughput

0.486

High

475836

EF1A1
Elongation factor 1-alpha 1

1

2

High-throughput

0.464

High

1379140

TIP60
Histone acetyltransferase Tip60

1

1

High-throughput

0.464

High

263416

PENG
Protein penguin

1

1

High-throughput

0.445

High

654390

DDX6
ATP-dependent RNA helicase me31b

1

3

High-throughput

0.445

High

1261362

Q7JQN4
RNA helicase

1

4

High-throughput

0.445

High

1263254

Q7JXU4
Nucleolar GTP-binding protein 2

1

3

High-throughput

0.445

High

1344154

Q8SY39
ATP-dependent RNA helicase DDX54

1

3

High-throughput

0.445

High

1378651

Q95WY3
Nucleolar protein 56

1

3

High-throughput

0.445

High

1464955

NOG1
Nucleolar GTP-binding protein 1

1

2

High-throughput

0.445

High

1471257

DDX18
Probable ATP-dependent RNA helicase pitchoune

1

7

High-throughput

0.445

High

1474948

RLP24
Probable ribosome biogenesis protein RLP24

1

1

High-throughput

0.445

High

1477264

NOC3L
Nucleolar complex protein 3

1

1

High-throughput

0.445

High

1477469

DDX47
ATP-dependent RNA helicase DDX47

1

4

High-throughput

0.445

High

1481549

Q9VM69
Nucleolar protein 58

1

3

High-throughput

0.445

High

1485781

Q9VXK5
Putative rRNA methyltransferase

1

1

High-throughput

0.445

High

1485786

Q9VZ88
AT07585p

1

2

High-throughput

0.445

High

1266374

Q7K4C2
LD46713p

1

1

High-throughput

0.439

High

1285603

Q86BJ0
Uncharacterized protein, isoform C

1

1

High-throughput

0.439

High

1485792

Q9W1A9
histone acetyltransferase

1

4

High-throughput

0.439

High

1485803

X2JDN0
Ellipsoid body open, isoform B

1

4

High-throughput

0.439

High

304276

ERD2
ER lumen protein-retaining receptor

1

0

High-throughput

0.426

High

652115

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

1

0

High-throughput

0.426

High

1483373

MBM
Protein mushroom body miniature

1

0

High-throughput

0.426

High

1485784

RRP12
RRP12-like protein

1

0

High-throughput

0.426

High

1485789

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.426

High

1485794

Q9W335
Translocon-associated protein subunit alpha

1

0

High-throughput

0.426

High

1485795

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.426

High

1485796

Q9W3N1
RH59310p

1

0

High-throughput

0.426

High

2678

A0A0B4LET0
Uncharacterized protein, isoform B

1

1

High-throughput

0.417

High

832174

RL27A
Large ribosomal subunit protein uL15

1

1

High-throughput

0.417

High

1268029

Q7KN74
Tetratricopeptide repeat domain 7, isoform A

1

2

High-throughput

0.417

High

1378402

Q95TZ1
GH20156p

1

1

High-throughput

0.417

High

1485772

Q9VVV6
LD45843p

1

1

High-throughput

0.417

High

1485799

Q9W5G1
Ellipsoid body open, isoform A

1

4

High-throughput

0.417

High

55481

A1Z9E3
Elongation factor Tu

1

1

High-throughput

0.407

High

55829

A1Z9K0
Uncharacterized protein, isoform B

1

2

High-throughput

0.407

High

58114

A1ZBE9
Methionine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.407

High

198100

PRS8
26S proteasome regulatory subunit 8

1

4

High-throughput

0.407

High

356905

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

3

High-throughput

0.407

High

438016

PYR1
Multifunctional protein r

1

1

High-throughput

0.407

High

473638

RAS1
Ras-like protein 1

1

1

High-throughput

0.407

High

597843

BICD
Protein bicaudal D

1

1

High-throughput

0.407

High

654908

MA205
205 kDa microtubule-associated protein

1

1

High-throughput

0.407

High

704407

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

1

High-throughput

0.407

High

773391

RFC1
Replication factor C subunit 1

1

3

High-throughput

0.407

High

782808

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

1

1

High-throughput

0.407

High

823802

SQH
Myosin regulatory light chain sqh

1

1

High-throughput

0.407

High

834878

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

1

High-throughput

0.407

High

875032

PRS4
26S proteasome regulatory subunit 4

1

5

High-throughput

0.407

High

875301

TCPG
T-complex protein 1 subunit gamma

1

2

High-throughput

0.407

High

1069778

Q0E931
GTP-binding protein 1

1

4

High-throughput

0.407

High

1070125

Q0E9E2
Pyruvate carboxylase

1

1

High-throughput

0.407

High

1173968

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

3

High-throughput

0.407

High

1176026

MCM4
DNA replication licensing factor MCM4

1

1

High-throughput

0.407

High

1234131

SARM1
NAD(+) hydrolase sarm1

1

1

High-throughput

0.407

High

1236907

Q6NP35
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.407

High

1265863

Q7K3J0
T-complex protein 1 subunit theta

1

1

High-throughput

0.407

High

1267744

Q7KMQ0
26S proteasome regulatory subunit 7

1

4

High-throughput

0.407

High

1285373

Y8611
Probable ATP-dependent RNA helicase CG8611

1

6

High-throughput

0.407

High

1344471

Q8SYG3
E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.407

High

1378502

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.407

High

1464468

Q9V3V6
26S proteasome regulatory complex subunit p50

1

5

High-throughput

0.407

High

1464883

Q9V405
26S proteasome regulatory subunit 6B

1

3

High-throughput

0.407

High

1465204

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.407

High

1465638

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.407

High

1466771

Q9V9Q4
LD43819p

1

1

High-throughput

0.407

High

1467972

Q9VAH7
N-terminal kinase-like protein

1

1

High-throughput

0.407

High

1468603

Q9VAX8
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.407

High

1472784

Q9VEH0
Aluminum tubes, isoform A

1

2

High-throughput

0.407

High

1473326

ATD3A
ATPase family AAA domain-containing protein 3A homolog

1

4

High-throughput

0.407

High

1474997

IPO9
Importin-9

1

2

High-throughput

0.407

High

1476303

Q9VHL2
T-complex protein 1 subunit eta

1

1

High-throughput

0.407

High

1476811

ARL8
ADP-ribosylation factor-like protein 8

1

1

High-throughput

0.407

High

1478466

Q9VJH2
Aspartyl-tRNA synthetase, mitochondrial, isoform A

1

2

High-throughput

0.407

High

1479373

Q9VKC1
IP16805p

1

2

High-throughput

0.407

High

1480047

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

2

High-throughput

0.407

High

1480091

Q9VKZ8
Ubiquitin carboxyl-terminal hydrolase

1

1

High-throughput

0.407

High

1481465

Q9VM49
Caper, isoform A

1

2

High-throughput

0.407

High

1482346

Q9VN44
FI07923p

1

2

High-throughput

0.407

High

1485767

Q9VUM1
U4/U6 small nuclear ribonucleoprotein Prp31

1

3

High-throughput

0.407

High

1485776

RS10B
Small ribosomal subunit protein eS10B

1

1

High-throughput

0.407

High

1485778

Q9VWI2
N(Alpha)-acetyltransferase 15/16, isoform A

1

2

High-throughput

0.407

High

1485785

RENT1
Regulator of nonsense transcripts 1 homolog

1

2

High-throughput

0.407

High

1485797

Q9W414
Regulatory particle triple-A ATPase 4

1

4

High-throughput

0.407

High

1485802

SYQ
Probable glutamine--tRNA ligase

1

1

High-throughput

0.407

High

1377492

Q95RF6
LD34461p

2

0

High-throughput

0.298

High

1484208

Q9VQI5
Interferon-related developmental regulator 1

2

0

High-throughput

0.298

High

393761

VIT1
Vitellogenin-1

1

0

High-throughput

0.265

Low

1484587

Q9VR26
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

1484759

CATIN
Splicing factor Cactin

1

0

High-throughput

0.265

Low

1485770

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.265

Low

1485771

DTBP1
Dysbindin protein homolog

1

0

High-throughput

0.265

Low

1485774

Q9VW52
Precursor RNA processing 3, isoform A

1

0

High-throughput

0.265

Low

1485780

ANX11
Annexin B11

1

0

High-throughput

0.265

Low

1485793

Q9W2S2
Autophagy-related 8a, isoform A

1

0

High-throughput

0.265

Low

1485800

GCP2
Gamma-tubulin complex component 2 homolog

1

0

High-throughput

0.265

Low

1479511

ZUC
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

1483907

GOLP3
Golgi phosphoprotein 3 homolog sauron

1

0

High-throughput

0.249

Low

1485766

PYRG
CTP synthase

1

0

High-throughput

0.249

Low

1267042

Q7KB18
Epoxide hydrolase

1

0

High-throughput

0.238

Low

1485791

Q9W144
FI06118p

1

0

High-throughput

0.238

Low

53179

A1Z7K8
AaRS-interacting multifunctional protein 1

1

0

High-throughput

0.232

Low

53720

A1Z843
Nodal modulator 3

1

0

High-throughput

0.232

Low

54635

A1Z8U0
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.232

Low

95266

E1JIH4
Uncharacterized protein, isoform D

1

0

High-throughput

0.232

Low

360593

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.232

Low

715167

CLH
Clathrin heavy chain

1

0

High-throughput

0.232

Low

786403

2ABA
Protein phosphatase PP2A 55 kDa regulatory subunit

1

0

High-throughput

0.232

Low

852238

COPB
Coatomer subunit beta

1

0

High-throughput

0.232

Low

852982

ACTZ
Actin-related protein 1

1

0

High-throughput

0.232

Low

909883

PFKA
ATP-dependent 6-phosphofructokinase

1

0

High-throughput

0.232

Low

911789

POLO
Serine/threonine-protein kinase polo

1

0

High-throughput

0.232

Low

1057360

ARL2
ADP-ribosylation factor-like protein 2

1

0

High-throughput

0.232

Low

1059184

ROP
Protein ROP

1

0

High-throughput

0.232

Low

1071057

Q0KIB3
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.232

Low

1175355

NETB
Netrin-B

1

0

High-throughput

0.232

Low

1176364

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

0

High-throughput

0.232

Low

1264050

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.232

Low

1265756

Q7K3H0
LD28067p

1

0

High-throughput

0.232

Low

1267856

Q7KN04
Spondin-1

1

0

High-throughput

0.232

Low

1268366

DYM
Dymeclin

1

0

High-throughput

0.232

Low

1268738

CCD1D
Probable cytochrome P450 12d1 distal, mitochondrial

1

0

High-throughput

0.232

Low

1321464

Q8MSW0
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

1344251

Q8SY53
GH11935p

1

0

High-throughput

0.232

Low

1346030

ENA
Protein enabled

1

0

High-throughput

0.232

Low

1346072

Q8T4G5
AFG3 like matrix AAA peptidase subunit 2, isoform A

1

0

High-throughput

0.232

Low

1346283

Q8T8W3
AT21416p

1

0

High-throughput

0.232

Low

1464813

Q9V3Z4
GH11341p

1

0

High-throughput

0.232

Low

1465146

API5
Apoptosis inhibitor 5 homolog

1

0

High-throughput

0.232

Low

1465477

Q9V455
Importin subunit alpha

1

0

High-throughput

0.232

Low

1468494

Q9VAW3
glutamine--fructose-6-phosphate transaminase

1

0

High-throughput

0.232

Low

1473045

Q9VEP0
Regulatory protein zeste

1

0

High-throughput

0.232

Low

1474184

ELP6
Elongator complex protein 6

1

0

High-throughput

0.232

Low

1477160

Q9VI53
LD44267p

1

0

High-throughput

0.232

Low

1477848

RAGP1
Ran GTPase-activating protein

1

0

High-throughput

0.232

Low

1478324

Q9VJD1
Glucosidase 2 subunit beta

1

0

High-throughput

0.232

Low

1479164

Q9VK56
ABC-type glutathione-S-conjugate transporter

1

0

High-throughput

0.232

Low

1479431

NFS1
Cysteine desulfurase, mitochondrial

1

0

High-throughput

0.232

Low

1481496

Q9VM57
Septin interacting protein 2, isoform A

1

0

High-throughput

0.232

Low

1482196

GMDS
GDP-mannose 4,6 dehydratase

1

0

High-throughput

0.232

Low

1483194

NUBP2
Cytosolic Fe-S cluster assembly factor Nubp2 homolog

1

0

High-throughput

0.232

Low

1483673

Q9VPX5
Vacuolar protein sorting-associated protein 29

1

0

High-throughput

0.232

Low

1484353

Q9VQL7
Fatty acid synthase

1

0

High-throughput

0.232

Low

1485370

Q9VS47
Lysosomal dipeptide transporter MFSD1

1

0

High-throughput

0.232

Low

1485444

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

1485765

FRL
Formin-like protein

1

0

High-throughput

0.232

Low

1485768

AIMP2
Probable aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.232

Low

1485769

Q9VV75
AT02348p

1

0

High-throughput

0.232

Low

1485773

FRIZ2
Frizzled-2

1

0

High-throughput

0.232

Low

1485775

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.232

Low

1485777

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

0

High-throughput

0.232

Low

1485779

Q9VWL0
Mec2

1

0

High-throughput

0.232

Low

1485782

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

1485783

Q9VXR5
ATP-binding cassette sub-family F member 2

1

0

High-throughput

0.232

Low

1485787

Q9VZU8
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.232

Low

1485788

Q9W0E4
Aminopeptidase

1

0

High-throughput

0.232

Low

1485790

Q9W0T7
Dis3 like 3'-5' exoribonuclease 2, isoform A

1

0

High-throughput

0.232

Low

1485798

Q9W4C1
IP13321p

1

0

High-throughput

0.232

Low

1485801

Q9XZ53
dolichyl-diphosphooligosaccharide--protein glycotransferase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025