Interactor 1: SGT2 (Q12118)
Small glutamine-rich tetratricopeptide repeat-containing protein 2 (SGT/UBP) (Viral protein U-binding protein)
Gene: SGT2

Interactor 2: MDY2 (Q12285)
Ubiquitin-like protein MDY2 (Golgi to ER traffic protein 5) (Mating-deficient protein 2) (Translation machinery-associated protein 24)
Gene: MDY2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 11283351, 10688190, 18719252, 20106980, 20850366, 21832041, 16554755, 27354063, 37968396, 20093466, 21619481, 17441508, 23142665, 23285234, 23297211, 24100326
Identification Methods two hybrid pooling approach, two hybrid, affinity chromatography technology, pull down, biochemical, x-ray crystallography, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification, solution state nmr and 1 others

more...

Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains SGTA_dimer~ubiquitin
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006620 - post-translational protein targeting to endoplasmic reticulum membrane
GO:0072380 - TRC complex
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 346
Sc

1 212
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024