HitPredict

Interactor 1: RRP6 (Q12149)
Exosome complex exonuclease RRP6 (Rrp6p) (EC 3.1.13.-) (Ribosomal RNA-processing protein 6)
Gene: RRP6

Interactor 2: RRP6 (Q12149)
Exosome complex exonuclease RRP6 (Rrp6p) (EC 3.1.13.-) (Ribosomal RNA-processing protein 6)
Gene: RRP6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 28539363, 31662437, 14759368
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_pol_A_exo1~DNA_pol_A_exo1, DNA_pol_A_exo1~HRDC, HRDC~HRDC, PMC2NT~PMC2NT
Common GO terms GO:0000166 - nucleotide binding
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000176 - nuclear exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
and 20 others

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Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 733
Sc

1 733
+ Hs
+ Sp
+ Hs
+ Dm
+ Hs

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Last updated: 15 Jul 2024