HitPredict

Interactor 1: F8VQD1 (F8VQD1)
Polybromo 1
Gene: Pbrm1

Interactor 2: KDM4B (Q91VY5)
Lysine-specific demethylase 4B (EC 1.14.11.66) (JmjC domain-containing histone demethylation protein 3B) (Jumonji domain-containing protein 2B) ([histone H3]-trimethyl-L-lysine(9) demethylase 4B)
Gene: KDM4B

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21445275
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1704 Mm			1 1086
+	Mm
		101540 F8VQD1_MOUSE (1-1704): 0: 1238: 100.00		KDM4C_MOUSE (4-1079): 0: 976: 52.25
+	Mm
		101539 F8VQD1_MOUSE (1-1704): 0: 1238: 100.00		KDM4A_MOUSE (1-1073): 0: 956: 49.17
+	Hs
		319248 PB1_HUMAN (1-1704): 0: 1223: 97.30		BRD1_HUMAN (528-1077): 9.84e-94: 324: 18.09
+	Hs
		782356 PB1_HUMAN (1-1704): 0: 1223: 97.30		KDM5C_HUMAN (5-88): 2.53e-14: 80.1: 28.57
+	Mm
		1111958 SMCA4_MOUSE (763-935): 1e-11: 72.6: 19.78		KDM4B_MOUSE (1-1086): 0: 1099: 100.00
+	Mm
		1111955 SMCA4_MOUSE (763-935): 1e-11: 72.6: 19.78		KDM4C_MOUSE (4-1079): 0: 976: 52.25
+	Mm
		1111949 SMCA4_MOUSE (763-935): 1e-11: 72.6: 19.78		KDM4A_MOUSE (1-1073): 0: 956: 49.17
+	Hs
		319124 DNMT1_HUMAN (845-1310): 1.45e-65: 248: 14.23		BRD1_HUMAN (528-1077): 9.84e-94: 324: 18.09
+	Hs
		600110 TAF1_HUMAN (457-978): 5.27e-60: 230: 15.81		BRPF1_HUMAN (478-1078): 1.17e-90: 318: 16.80
+	Dm
		1177412 ASH1_DROME (1100-1392): 1.01e-38: 161: 18.52		BRDH_DROME (502-1078): 9.69e-93: 326: 16.64
+	Hs
		631537 BRD2_HUMAN (3-169): 2.99e-18: 93.2: 18.02		JARD2_HUMAN (76-496): 2.44e-92: 323: 21.95
+	Sc
		977700 RSC2_YEAST (45-183): 4.85e-14: 79.8: 19.42		GIS1_YEAST (15-626): 7.96e-99: 335: 20.47
+	Hs
		631382 BRD2_HUMAN (3-169): 2.99e-18: 93.2: 18.02		BRPF1_HUMAN (478-1078): 1.17e-90: 318: 16.80
+	Sc
		696247 STH1_YEAST (182-278): 1.03e-09: 65.9: 35.05		GIS1_YEAST (15-626): 7.96e-99: 335: 20.47
+	Sc
		969440 RSC4_YEAST (331-882): 7.18e-43: 169: 14.75		NTO1_YEAST (740-878): 8.46e-23: 107: 38.73
+	Sc
		728780 BDF1_YEAST (6-183): 3.66e-23: 109: 14.44		NTO1_YEAST (740-878): 8.46e-23: 107: 38.73
+	Hs
		782381 BRD8_HUMAN (631-805): 1.99e-16: 87.8: 18.23		KDM5C_HUMAN (5-88): 2.53e-14: 80.1: 28.57
+	Hs
		666549 BRD8_HUMAN (631-805): 1.99e-16: 87.8: 18.23		KDM5A_HUMAN (5-57): 8.09e-13: 75.4: 32.08
+	Hs
		782389 ASH1L_HUMAN (557-669): 5.42e-14: 80.1: 30.97		KDM5C_HUMAN (5-88): 2.53e-14: 80.1: 28.57
+	Hs
		782323 SMCA4_HUMAN (779-935): 3.55e-10: 67.6: 19.76		KDM5C_HUMAN (5-88): 2.53e-14: 80.1: 28.57