Interactor 1: SRBP2 (Q12772)
Sterol regulatory element-binding protein 2 (SREBP-2) (Class D basic helix-loop-helix protein 2) (bHLHd2) (Sterol regulatory element-binding transcription factor 2) [Cleaved into: Processed sterol regulatory element-binding protein 2 (Transcription factor SREBF2)]
Gene: SREBF2

Interactor 2: FHL2 (Q14192)
Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3)
Gene: FHL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.858

The method score is based on:

Property Details
Experiments 32296183, 33961781, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, validated two hybrid, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~LIM
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1141
Hs

1 279
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Last updated: 15 Jul 2024