Interactor 1: AKP13 (Q12802)
A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47)
Gene: AKAP13
Interactor 2: ARHGI (Q6ZSZ5)
Rho guanine nucleotide exchange factor 18 (114 kDa Rho-specific guanine nucleotide exchange factor) (p114-Rho-GEF) (p114RhoGEF) (Septin-associated RhoGEF) (SA-RhoGEF)
Gene: ARHGEF18
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35271311 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH_16~PH_16, PH_16~RhoGEF, RhoGEF~RhoGEF |
| Common GO terms | GO:0005085 - guanyl-nucleotide exchange factor activity GO:0005829 - cytosol GO:0035023 - regulation of Rho protein signal transduction GO:0046872 - metal ion binding |
| Homologous interactions | 16 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
