HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: HP1B3 (Q5SSJ5)
Heterochromatin protein 1-binding protein 3 (Protein HP1-BP74)
Gene: HP1BP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	36089195, 29044188
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Linker_histone
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0006334 - nucleosome assembly
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 553
+	Hs
		998409 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		HP1B3_HUMAN (1-553): 0: 867: 100.00
+	Hs
		1210463 H32_HUMAN (1-136): 5.34e-59: 180: 97.06		HP1B3_HUMAN (1-553): 0: 867: 100.00
+	Hs
		1210458 H3C_HUMAN (1-136): 2e-56: 173: 95.59		HP1B3_HUMAN (1-553): 0: 867: 100.00
+	Hs
		883568 CENPA_HUMAN (9-133): 2.43e-45: 146: 50.76		HP1B3_HUMAN (1-553): 0: 867: 100.00