HitPredict

Interactor 1: BPTF (Q12830)
Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen)
Gene: BPTF

Interactor 2: PWP2A (Q96N64)
PWWP domain-containing protein 2A
Gene: PWWP2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0035064 - methylated histone binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 3046 Hs			1 755
+	Hs
		1018645 CHD3_HUMAN (356-439): 2.17e-18: 95.6: 33.33		PWP2A_HUMAN (1-755): 5.64e-106: 343: 100.00
+	Hs
		1353937 BAZ2A_HUMAN (2341-3038): 1.92e-43: 178: 15.08		DNM3B_HUMAN (444-740): 8.42e-62: 224: 18.33
+	Hs
		631469 BRD2_HUMAN (2746-3032): 7.09e-28: 125: 20.14		PWP2B_HUMAN (159-755): 9.75e-67: 233: 31.55
+	Hs
		1067007 BRD3_HUMAN (2905-3032): 5.45e-26: 119: 27.07		PWP2B_HUMAN (159-755): 9.75e-67: 233: 31.55
+	Hs
		1123371 BRDT_HUMAN (2931-3032): 1.52e-24: 115: 32.71		PWP2B_HUMAN (159-755): 9.75e-67: 233: 31.55
+	Hs
		244572 BRD4_HUMAN (2936-3028): 1.03e-10: 70.1: 41.05		PWP2B_HUMAN (159-755): 9.75e-67: 233: 31.55
+	Hs
		554303 EP300_HUMAN (1930-3035): 2.55e-49: 197: 11.62		MUC1_HUMAN (76-652): 1.04e-15: 83.8: 10.88
+	Hs
		998710 EP300_HUMAN (1930-3035): 2.55e-49: 197: 11.62		MDC1_HUMAN (4-618): 1.16e-11: 70.7: 10.38
+	Hs
		1057027 TRI33_HUMAN (2455-3045): 2.57e-42: 173: 12.58		MDC1_HUMAN (4-618): 1.16e-11: 70.7: 10.38
+	Dm
		113976 M9PB30_DROME (1527-2342): 1.77e-31: 139: 8.91		M9PB30_DROME (4-413): 6.75e-10: 65.3: 12.07
+	Hs
		1067006 BRD3_HUMAN (2905-3032): 5.45e-26: 119: 27.07		NIPBL_HUMAN (230-664): 2.34e-15: 82.8: 13.39
+	Hs
		631425 BRD2_HUMAN (2746-3032): 7.09e-28: 125: 20.14		MDC1_HUMAN (4-618): 1.16e-11: 70.7: 10.38
+	Hs
		1056838 BRD3_HUMAN (2905-3032): 5.45e-26: 119: 27.07		MDC1_HUMAN (4-618): 1.16e-11: 70.7: 10.38
+	Hs
		1264771 TITIN_HUMAN (1259-2946): 5.69e-25: 117: 7.72		TITIN_HUMAN (32-662): 9.5e-09: 61.5: 10.97
+	Hs
		244571 BRD4_HUMAN (2936-3028): 1.03e-10: 70.1: 41.05		NIPBL_HUMAN (230-664): 2.34e-15: 82.8: 13.39
+	Hs
		1056910 CBP_HUMAN (1558-2670): 1.8e-12: 76: 8.05		MDC1_HUMAN (4-618): 1.16e-11: 70.7: 10.38
+	Hs
		244438 BRD4_HUMAN (2936-3028): 1.03e-10: 70.1: 41.05		MDC1_HUMAN (4-618): 1.16e-11: 70.7: 10.38
+	Mm
		1351630 PCLO_MOUSE (944-2887): 1.71e-11: 72.9: 8.40		PCLO_MOUSE (5-649): 1.32e-09: 64.2: 11.62