Protein: SPIN1
Spindlin-1 (Ovarian cancer-related protein) (Spindlin1)

Gene: SPIN1
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q9Y657

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005819 - spindle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1409761

SPI2B
Spindlin-2B

3

1

High-throughput

0.861

High

1201236

SPIN4
Spindlin-4

2

1

High-throughput

0.789

High

1414060

SPNDC
Spindlin interactor and repressor of chromatin-binding protein

4

2

High-throughput

0.691

High

1449088

TOPRS
E3 ubiquitin-protein ligase Topors

4

1

High-throughput

0.691

High

1459138

CGBP1
CGG triplet repeat-binding protein 1

4

1

High-throughput

0.691

High

662332

PAX3
Paired box protein Pax-3

3

0

High-throughput

0.638

High

1327490

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

3

0

High-throughput

0.638

High

1416205

SCNM1
Sodium channel modifier 1

3

0

High-throughput

0.638

High

1230923

Z324B
Zinc finger protein 324B

2

1

High-throughput

0.628

High

1065518

SSRP1
FACT complex subunit SSRP1

2

3

High-throughput

0.611

High

1288026

YRDC
Threonylcarbamoyl-AMP synthase

3

1

High-throughput

0.609

High

1436837

WDR76
WD repeat-containing protein 76

2

2

High-throughput

0.601

High

1088760

SF3A3
Splicing factor 3A subunit 3

2

0

High-throughput

0.585

High

972185

1433E
14-3-3 protein epsilon

2

0

Small-scale

0.559

High

415968

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.558

High

249801

DOK2
Docking protein 2

2

0

High-throughput

0.547

High

1116707

RIN1
Ras and Rab interactor 1

2

0

High-throughput

0.547

High

859526

RL5
Large ribosomal subunit protein uL18

1

0

Small-scale

0.537

High

732747

ARRB2
Beta-arrestin-2

1

2

High-throughput

0.536

High

882588

ARRB1
Beta-arrestin-1

1

2

High-throughput

0.536

High

1163320

H2B2E
Histone H2B type 2-E

1

1

High-throughput

0.536

High

1491804

CDY2
Testis-specific chromodomain protein Y 2

1

2

High-throughput

0.536

High

63279

VP37C
Vacuolar protein sorting-associated protein 37C

1

0

High-throughput

0.513

High

136160

PLK4
Serine/threonine-protein kinase PLK4

1

0

High-throughput

0.513

High

361390

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

463275

YES
Tyrosine-protein kinase Yes

1

0

High-throughput

0.513

High

539651

PYGM
Glycogen phosphorylase, muscle form

1

0

High-throughput

0.513

High

641081

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

0

High-throughput

0.513

High

867836

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

0

High-throughput

0.513

High

1126848

SLBP
Histone RNA hairpin-binding protein

1

0

High-throughput

0.513

High

1415650

RIOK2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.513

High

1437090

AGO3
Protein argonaute-3

1

0

High-throughput

0.513

High

1491803

SAR1B
Small COPII coat GTPase SAR1B

1

0

High-throughput

0.513

High

481424

HMGB1
High mobility group protein B1

1

3

Small-scale

0.508

High

1396951

ANM6
Protein arginine N-methyltransferase 6

1

2

High-throughput

0.508

High

1316671

D107A
Beta-defensin 107

1

2

High-throughput

0.489

High

316230

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

349308

LATS1
Serine/threonine-protein kinase LATS1

1

2

High-throughput

0.479

High

401781

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

543311

UBL4A
Ubiquitin-like protein 4A

1

1

High-throughput

0.479

High

762075

GRK5
G protein-coupled receptor kinase 5

1

2

High-throughput

0.479

High

807636

IF4A3
Eukaryotic initiation factor 4A-III

1

1

High-throughput

0.479

High

888423

MCM2
DNA replication licensing factor MCM2

1

3

High-throughput

0.479

High

905350

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.479

High

961133

MGN
Protein mago nashi homolog

1

1

High-throughput

0.479

High

971373

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

999009

H31
Histone H3.1

1

2

High-throughput

0.479

High

1017338

H33
Histone H3.3

1

2

High-throughput

0.479

High

1127295

RBM39
RNA-binding protein 39

1

2

High-throughput

0.479

High

1217782

GFI1B
Zinc finger protein Gfi-1b

1

2

Small-scale

0.479

High

1258994

H32
Histone H3.2

1

2

Small-scale

0.479

High

1385940

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

1396886

SNX27
Sorting nexin-27

1

2

High-throughput

0.479

High

1407982

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.479

High

1447048

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

1452584

BCLF1
Bcl-2-associated transcription factor 1

1

1

High-throughput

0.479

High

1459484

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1490730

ST38L
Serine/threonine-protein kinase 38-like

1

2

High-throughput

0.479

High

1490961

TR150
Thyroid hormone receptor-associated protein 3

1

1

High-throughput

0.479

High

1491363

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.479

High

1491520

SP16H
FACT complex subunit SPT16

1

2

High-throughput

0.479

High

228403

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.458

High

257524

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

320195

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

348018

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

350200

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.458

High

414929

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

447632

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

587543

TFE2
Transcription factor E2-alpha

1

0

High-throughput

0.458

High

607278

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

957577

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

992670

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.458

High

1098216

DUS8
Dual specificity protein phosphatase 8

1

0

High-throughput

0.458

High

1141120

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1156920

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1229805

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1247068

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

1294134

DDX42
ATP-dependent RNA helicase DDX42

1

0

High-throughput

0.458

High

1308496

VRK3
Serine/threonine-protein kinase VRK3

1

0

High-throughput

0.458

High

1356423

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

0

High-throughput

0.458

High

1364749

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1401478

CIC
Protein capicua homolog

1

0

High-throughput

0.458

High

1403160

CRBN
Protein cereblon

1

0

Small-scale

0.458

High

1431681

GAN
Gigaxonin

1

0

High-throughput

0.458

High

1439028

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

0

High-throughput

0.458

High

1453565

PD1L1
Programmed cell death 1 ligand 1

1

0

Small-scale

0.458

High

1461951

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

530678

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

1103482

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.445

High

294602

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

1215924

RC3H1
Roquin-1

1

1

High-throughput

0.437

High

1438114

RC3H2
Roquin-2

1

3

High-throughput

0.437

High

354818

PAK4
Serine/threonine-protein kinase PAK 4

1

0

High-throughput

0.426

High

1209854

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

87566

OSCRI
SCRIB overlapping open reading frame protein

1

2

High-throughput

0.407

High

51339

NTM2F
NUT family member 2F

1

0

High-throughput

0.279

Low

1406674

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.279

Low

1451234

CUED1
CUE domain-containing protein 1

1

0

High-throughput

0.279

Low

50876

NDUF8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8

1

0

Small-scale

0.249

Low

402440

GBA1
Lysosomal acid glucosylceramidase

1

0

Small-scale

0.249

Low

1491499

TRI17
E3 ubiquitin-protein ligase TRIM17

1

0

Small-scale

0.249

Low

636785

PTN
Pleiotrophin

1

0

High-throughput

0.238

Low

1446809

CASS4
Cas scaffolding protein family member 4

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025