HitPredict

Interactor 1: F8W6L3 (F8W6L3)
Kinesin light chain
Gene: KLC1

Interactor 2: KINH (P33176)
Kinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC)
Gene: KIF5B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005871 - kinesin complex GO:0005874 - microtubule GO:0007018 - microtubule-based movement
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 576 Hs			1 963
+	Hs
		702891 KLC1_HUMAN (1-569): 1.96e-105: 330: 95.08		KINH_HUMAN (1-963): 5.26e-144: 455: 100.00
+	Hs
		702974 KLC2_HUMAN (5-496): 3.5e-89: 289: 73.98		KINH_HUMAN (1-963): 5.26e-144: 455: 100.00
+	Hs
		174664 OGT1_HUMAN (130-575): 7.38e-43: 166: 13.00		KINH_HUMAN (1-963): 5.26e-144: 455: 100.00
+	Hs
		702983 KLC4_HUMAN (369-571): 5.71e-15: 80.1: 20.39		KINH_HUMAN (1-963): 5.26e-144: 455: 100.00
+	Hs
		702921 KLC3_HUMAN (378-571): 2.4e-12: 71.2: 19.29		KINH_HUMAN (1-963): 5.26e-144: 455: 100.00
+	Hs
		992334 KLC1_HUMAN (1-569): 1.96e-105: 330: 95.08		KIF5A_HUMAN (599-962): 8.85e-14: 77.9: 11.72
+	Mm
		1143114 Q8CD76_MOUSE (1-569): 4.19e-105: 331: 93.15		KINH_MOUSE (680-963): 1.95e-11: 70.2: 9.60
+	Mm
		702846 Q8CD76_MOUSE (1-569): 4.19e-105: 331: 93.15		KIF5A_MOUSE (575-960): 4.34e-11: 69.1: 8.11
+	Hs
		229856 KLC1_HUMAN (1-569): 1.96e-105: 330: 95.08		KIF5C_HUMAN (658-961): 7.72e-11: 68.3: 12.62
+	Hs
		1017559 KLC2_HUMAN (5-496): 3.5e-89: 289: 73.98		KIF5A_HUMAN (599-962): 8.85e-14: 77.9: 11.72
+	Hs
		229887 KLC2_HUMAN (5-496): 3.5e-89: 289: 73.98		KIF5C_HUMAN (658-961): 7.72e-11: 68.3: 12.62
+	Ce
		712252 KLC_CAEEL (16-505): 6.12e-84: 273: 63.13		KINH_CAEEL (578-913): 2.31e-14: 79.8: 27.99
+	Dm
		566087 KLC_DROME (16-530): 2.99e-81: 265: 68.16		KINH_DROME (575-961): 2.46e-10: 66.7: 9.90
+	Ce
		712255 Q21592_CAEEL (22-518): 2.42e-74: 247: 42.12		KINH_CAEEL (578-913): 2.31e-14: 79.8: 27.99
+	Rn
		881490 OGT1_RAT (130-575): 8.25e-43: 166: 13.00		KINH_RAT (680-963): 2.5e-11: 69.8: 9.27
+	Dm
		115868 M9PGT5_DROME (228-559): 1.06e-16: 85.8: 14.25		KINH_DROME (575-961): 2.46e-10: 66.7: 9.90
+	Hs
		1017539 KLC3_HUMAN (378-571): 2.4e-12: 71.2: 19.29		KIF5A_HUMAN (599-962): 8.85e-14: 77.9: 11.72
+	Hs
		229891 KLC4_HUMAN (369-571): 5.71e-15: 80.1: 20.39		KIF5C_HUMAN (658-961): 7.72e-11: 68.3: 12.62
+	Mm
		660001 KLC3_MOUSE (378-571): 1.02e-12: 72.8: 19.29		KIF5C_MOUSE (659-962): 1.3e-10: 67.5: 12.34
+	Hs
		229869 KLC3_HUMAN (378-571): 2.4e-12: 71.2: 19.29		KIF5C_HUMAN (658-961): 7.72e-11: 68.3: 12.62