HitPredict

Interactor 1: KIF5A (Q12840)
Kinesin heavy chain isoform 5A (Kinesin heavy chain neuron-specific 1) (Neuronal kinesin heavy chain) (NKHC)
Gene: KIF5A

Interactor 2: KLC2 (Q9H0B6)
Kinesin light chain 2 (KLC 2)
Gene: KLC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	10491391, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005871 - kinesin complex GO:0005874 - microtubule GO:0007018 - microtubule-based movement GO:0016020 - membrane and 1 others more... GO:0019894 - kinesin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1032 Hs			1 622
+	Mm
		702846 KIF5A_MOUSE (1-1032): 6.83e-152: 479: 97.29		Q8CD76_MOUSE (1-593): 7.15e-105: 332: 67.71
+	Hs
		1017539 KIF5A_HUMAN (1-1032): 1e-154: 487: 100.00		KLC3_HUMAN (363-616): 1.47e-16: 84.7: 21.78
+	Hs
		992334 KIF5A_HUMAN (1-1032): 1e-154: 487: 100.00		KLC1_HUMAN (406-586): 8.56e-10: 63.5: 12.50
+	Hs
		231604 KIF1B_HUMAN (6-757): 2.78e-109: 376: 23.61		TMTC1_HUMAN (73-507): 1.74e-41: 163: 13.79
+	Hs
		150089 KIF1C_HUMAN (6-668): 1.81e-96: 332: 23.86		UTY_HUMAN (126-599): 3.47e-48: 184: 13.94
+	Hs
		229887 KIF5C_HUMAN (535-1017): 1.02e-14: 81: 9.20		KLC2_HUMAN (1-622): 1.59e-128: 393: 100.00
+	Hs
		702974 KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45		KLC2_HUMAN (1-622): 1.59e-128: 393: 100.00
+	Hs
		1160005 KI13B_HUMAN (7-730): 3.75e-110: 378: 23.68		KLC3_HUMAN (363-616): 1.47e-16: 84.7: 21.78
+	Ce
		712252 KINH_CAEEL (4-762): 1.74e-99: 334: 44.33		KLC_CAEEL (312-620): 1.61e-24: 109: 17.35
+	Hs
		229891 KIF5C_HUMAN (535-1017): 1.02e-14: 81: 9.20		KLC4_HUMAN (7-618): 1.11e-105: 334: 69.13
+	Mm
		1143114 KINH_MOUSE (623-1016): 3.55e-14: 79.5: 10.00		Q8CD76_MOUSE (1-593): 7.15e-105: 332: 67.71
+	Ce
		712255 KINH_CAEEL (4-762): 1.74e-99: 334: 44.33		Q21592_CAEEL (406-583): 9.87e-11: 66.6: 9.79
+	Rn
		881490 KINH_RAT (623-1016): 2.52e-14: 79.9: 10.25		OGT1_RAT (58-526): 2.74e-51: 192: 16.63
+	Hs
		174664 KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45		OGT1_HUMAN (58-526): 3.14e-51: 192: 16.63
+	Mm
		660001 KIF5C_MOUSE (477-1017): 2.72e-15: 83: 8.63		KLC3_MOUSE (363-617): 9.36e-17: 85.5: 22.08
+	Hs
		229869 KIF5C_HUMAN (535-1017): 1.02e-14: 81: 9.20		KLC3_HUMAN (363-616): 1.47e-16: 84.7: 21.78
+	Hs
		702921 KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45		KLC3_HUMAN (363-616): 1.47e-16: 84.7: 21.78
+	Hs
		229856 KIF5C_HUMAN (535-1017): 1.02e-14: 81: 9.20		KLC1_HUMAN (406-586): 8.56e-10: 63.5: 12.50
+	Hs
		702891 KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45		KLC1_HUMAN (406-586): 8.56e-10: 63.5: 12.50
+	Hs
		101750 KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45		F8W6L3_HUMAN (406-586): 1.16e-09: 63.2: 12.50