Protein: PRR5
Proline-rich protein 5 (Protein observed with Rictor-1) (Protor-1)

Gene: PRR5
Organism: Homo sapiens
Interactions: 48
UniProt ID: P85299

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0007010 - cytoskeleton organization
GO:0030307 - positive regulation of cell growth
GO:0031669 - cellular response to nutrient levels
GO:0031932 - TORC2 complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1017551

RICTR
Rapamycin-insensitive companion of mTOR

4

2

Small-scale

0.696

High

729747

1433B
14-3-3 protein beta/alpha

4

6

High-throughput

0.678

High

839241

MTOR
Serine/threonine-protein kinase mTOR

3

2

Small-scale

0.667

High

690904

1433T
14-3-3 protein theta

3

6

High-throughput

0.650

High

966194

1433G
14-3-3 protein gamma

3

6

High-throughput

0.650

High

1017544

1433F
14-3-3 protein eta

3

6

High-throughput

0.643

High

730509

1433S
14-3-3 protein sigma

2

6

High-throughput

0.611

High

971402

1433E
14-3-3 protein epsilon

3

0

High-throughput

0.606

High

169513

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

0

High-throughput

0.580

High

1017550

DESI1
Desumoylating isopeptidase 1

2

0

High-throughput

0.580

High

1017545

DLG1
Disks large homolog 1

2

0

Small-scale

0.569

High

798991

BRCA1
Breast cancer type 1 susceptibility protein

2

1

Small-scale

0.566

High

1017558

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

1

Small-scale

0.554

High

1017560

LST8
Target of rapamycin complex subunit LST8

1

2

Small-scale

0.554

High

1017559

MEP50
Methylosome protein WDR77

1

1

Small-scale

0.500

High

162541

ANM5
Protein arginine N-methyltransferase 5

1

0

Small-scale

0.479

High

1017542

OTUD4
OTU domain-containing protein 4

1

0

Small-scale

0.479

High

126545

RHOD
Rho-related GTP-binding protein RhoD

1

5

High-throughput

0.479

High

988273

RAC1
Ras-related C3 botulinum toxin substrate 1

1

3

High-throughput

0.479

High

990095

1433Z
14-3-3 protein zeta/delta

1

6

High-throughput

0.479

High

1015365

RHOG
Rho-related GTP-binding protein RhoG

1

2

High-throughput

0.479

High

1017563

RHOF
Rho-related GTP-binding protein RhoF

1

4

High-throughput

0.479

High

375405

RASK
GTPase KRas

1

0

High-throughput

0.458

High

623282

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

High-throughput

0.458

High

1017543

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1017546

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1017549

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

601236

RHOQ
Rho-related GTP-binding protein RhoQ

1

3

High-throughput

0.437

High

1017547

RHOH
Rho-related GTP-binding protein RhoH

1

3

High-throughput

0.437

High

1017561

RHOJ
Rho-related GTP-binding protein RhoJ

1

3

High-throughput

0.437

High

637456

FLNA
Filamin-A

1

0

Small-scale

0.426

High

860162

RS9
Small ribosomal subunit protein uS4

1

0

Small-scale

0.426

High

1017554

USBP1
Harmonin-binding protein USHBP1

2

0

High-throughput

0.316

High

1017564

CTNA3
Catenin alpha-3

2

0

High-throughput

0.316

High

1017566

GPSM3
G-protein-signaling modulator 3

2

0

High-throughput

0.316

High

256609

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

0

High-throughput

0.279

Low

964849

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.279

Low

1017553

CIR1
Corepressor interacting with RBPJ 1

1

0

High-throughput

0.279

Low

1017555

GIMA1
GTPase IMAP family member 1

1

0

High-throughput

0.279

Low

1017557

KCD12
BTB/POZ domain-containing protein KCTD12

1

0

High-throughput

0.279

Low

1017541

RBM10
RNA-binding protein 10

1

0

Small-scale

0.261

Low

1017556

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

0

Small-scale

0.261

Low

710172

EPHA2
Ephrin type-A receptor 2

1

0

High-throughput

0.249

Low

1017548

OCLN
Occludin

1

0

High-throughput

0.249

Low

1017562

RC3H2
Roquin-2

1

0

High-throughput

0.249

Low

1017565

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

996660

TBA1B
Tubulin alpha-1B chain

1

0

Small-scale

0.232

Low

1017552

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025