Interactor 1: STX4 (Q12846)
Syntaxin-4 (Renal carcinoma antigen NY-REN-31)
Gene: STX4

Interactor 2: VAMP3 (Q15836)
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)
Gene: VAMP3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 25416956, 16189514, 12828989, 10820264, 34079125, 12130530, 32296183, 35271311, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, proximity labelling technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SNARE~Synaptobrevin, Synaptobrevin~Syntaxin
Common GO terms GO:0005484 - SNAP receptor activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006887 - exocytosis
GO:0006906 - vesicle fusion
and 8 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024