HitPredict

Interactor 1: STX4 (Q12846)
Syntaxin-4 (Renal carcinoma antigen NY-REN-31)
Gene: STX4

Interactor 2: STXB5 (Q5T5C0)
Syntaxin-binding protein 5 (Lethal(2) giant larvae protein homolog 3) (Tomosyn-1)
Gene: STXBP5

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.653

Property	Details
Experiments	12832401, 34079125, 25244094
Identification Methods	pull down, two hybrid, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006887 - exocytosis GO:0008021 - synaptic vesicle GO:0017157 - regulation of exocytosis and 1 others more... GO:0031201 - SNARE complex
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 297 Hs			1 1151
+	Hs
		699268 STX2_HUMAN (1-295): 4.47e-72: 225: 42.57		STXB5_HUMAN (1-1151): 0: 1143: 100.00
+	Hs
		1083937 STX1A_HUMAN (1-293): 1.9e-70: 221: 43.20		STXB5_HUMAN (1-1151): 0: 1143: 100.00
+	Mm
		936826 STX4_MOUSE (1-295): 1.19e-66: 211: 90.51		STXB5_MOUSE (1-1151): 0: 1127: 96.88
+	Hs
		1030154 STX3_HUMAN (1-295): 6.64e-57: 186: 38.31		STXB5_HUMAN (1-1151): 0: 1143: 100.00
+	Hs
		269433 STX11_HUMAN (1-282): 4.21e-53: 176: 27.18		STXB5_HUMAN (1-1151): 0: 1143: 100.00
+	Hs
		1133592 STX19_HUMAN (1-269): 8.86e-52: 173: 29.30		STXB5_HUMAN (1-1151): 0: 1143: 100.00
+	Hs
		178582 STX7_HUMAN (31-291): 4.47e-50: 167: 23.95		STXB5_HUMAN (1-1151): 0: 1143: 100.00
+	Hs
		1133591 STX12_HUMAN (34-279): 2.35e-49: 166: 25.00		STXB5_HUMAN (1-1151): 0: 1143: 100.00
+	Hs
		699292 STX2_HUMAN (1-295): 4.47e-72: 225: 42.57		STB5L_HUMAN (1-1151): 0: 1051: 63.82
+	Hs
		1233518 STX19_HUMAN (1-269): 8.86e-52: 173: 29.30		STB5L_HUMAN (1-1151): 0: 1051: 63.82
+	Hs
		1205402 STX12_HUMAN (34-279): 2.35e-49: 166: 25.00		STB5L_HUMAN (1-1151): 0: 1051: 63.82
+	Ce
		183454 STX1A_CAEEL (2-291): 5.07e-70: 220: 36.90		Q14DX2_CAEEL (14-1151): 0: 802: 34.99
+	Hs
		1017639 STX4_HUMAN (1-297): 3e-70: 221: 100.00		L2GL1_HUMAN (35-1142): 0: 697: 25.19
+	Hs
		1030142 STX3_HUMAN (1-295): 6.64e-57: 186: 38.31		L2GL1_HUMAN (35-1142): 0: 697: 25.19
+	Hs
		178544 STX7_HUMAN (31-291): 4.47e-50: 167: 23.95		L2GL1_HUMAN (35-1142): 0: 697: 25.19
+	Sc
		699533 SSO1_YEAST (18-275): 2.01e-45: 156: 23.57		SRO7_YEAST (11-676): 2.57e-68: 251: 15.95