HitPredict

Interactor 1: CHD3 (Q12873)
Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)
Gene: CHD3

Interactor 2: ZMYD8 (Q9ULU4)
MYND-type zinc finger-containing chromatin reader ZMYND8 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Protein kinase C-binding protein 1) (Rack7) (Transcription coregulator ZMYND8) (Zinc finger MYND domain-containing protein 8)
Gene: ZMYND8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	28977666, 31753913
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Chromo~PHD, Bromodomain~PHD, PHD~PHD
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus and 2 others more... GO:0005737 - cytoplasm GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2000 Hs			1 1186
+	Hs
		1255051 CHD5_HUMAN (43-1961): 0: 1610: 66.45		ZMYD8_HUMAN (1-1186): 0: 1251: 100.00
+	Hs
		1059940 CHD4_HUMAN (132-1922): 0: 1552: 69.84		ZMYD8_HUMAN (1-1186): 0: 1251: 100.00
+	Hs
		1018704 CHD3_HUMAN (1-2000): 0: 1917: 100.00		BAZ1A_HUMAN (5-252): 1.74e-36: 152: 14.63
+	Hs
		1017286 CHD3_HUMAN (1-2000): 0: 1917: 100.00		BPTF_HUMAN (57-256): 6.93e-34: 144: 19.81
+	Hs
		600135 CHD3_HUMAN (1-2000): 0: 1917: 100.00		TAF1_HUMAN (14-254): 1.28e-24: 114: 20.57
+	Hs
		1018557 CHD3_HUMAN (1-2000): 0: 1917: 100.00		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57
+	Hs
		1255033 CHD5_HUMAN (43-1961): 0: 1610: 66.45		PHIP_HUMAN (152-648): 3.22e-48: 191: 14.68
+	Hs
		331813 CHD4_HUMAN (132-1922): 0: 1552: 69.84		NSD2_HUMAN (17-359): 5.44e-55: 212: 17.31
+	Hs
		1017327 CHD5_HUMAN (43-1961): 0: 1610: 66.45		BPTF_HUMAN (57-256): 6.93e-34: 144: 19.81
+	Hs
		1059760 CHD4_HUMAN (132-1922): 0: 1552: 69.84		PHIP_HUMAN (152-648): 3.22e-48: 191: 14.68
+	Hs
		1059944 CHD4_HUMAN (132-1922): 0: 1552: 69.84		TRI33_HUMAN (12-288): 1.97e-42: 171: 22.09
+	Hs
		1059928 CHD4_HUMAN (132-1922): 0: 1552: 69.84		BAZ2A_HUMAN (82-251): 2.51e-37: 155: 18.50
+	Hs
		1017295 CHD4_HUMAN (132-1922): 0: 1552: 69.84		BPTF_HUMAN (57-256): 6.93e-34: 144: 19.81
+	Hs
		1059704 CHD4_HUMAN (132-1922): 0: 1552: 69.84		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57
+	Hs
		1317720 CHD8_HUMAN (84-1804): 0: 851: 22.96		NSD3_HUMAN (3-359): 2.43e-44: 177: 14.64
+	Sc
		697429 CHD1_YEAST (539-1691): 0: 817: 29.78		GCN5_YEAST (120-252): 1.1e-33: 137: 23.88
+	Hs
		1199201 CHD8_HUMAN (84-1804): 0: 851: 22.96		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57
+	Mm
		101401 SMCA5_MOUSE (612-1612): 0: 781: 28.28		F8VPM0_MOUSE (82-251): 2.12e-37: 155: 19.56
+	Hs
		1199209 CHD7_HUMAN (503-1804): 0: 837: 28.86		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57
+	Sc
		697375 CHD1_YEAST (539-1691): 0: 817: 29.78		BDF1_YEAST (122-265): 3.31e-23: 108: 14.77