Protein: GLRX3
Glutaredoxin-3 (PKC-interacting cousin of thioredoxin) (PICOT) (PKC-theta-interacting protein) (PKCq-interacting protein) (Thioredoxin-like protein 2)

Gene: GLRX3
Organism: Homo sapiens
Interactions: 202
UniProt ID: O76003

Gene Ontology (top 5):
GO:0002026 - regulation of the force of heart contraction
GO:0003723 - RNA binding
GO:0005080 - protein kinase C binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

300257

BOLA1
BolA-like protein 1

7

20

High-throughput

0.971

High

300074

GLRX3
Glutaredoxin-3

3

17

Small-scale

0.854

High

300237

BOLA2
BolA-like protein 2

3

20

Small-scale

0.849

High

300156

BOLA3
BolA-like protein 3

2

20

High-throughput

0.783

High

300165

CPIN1
Anamorsin

12

5

Small-scale

0.763

High

300114

GRN
Progranulin

5

10

High-throughput

0.728

High

300077

RGS20
Regulator of G-protein signaling 20

5

1

High-throughput

0.726

High

300220

KR412
Keratin-associated protein 4-12

4

20

High-throughput

0.705

High

300116

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

2

High-throughput

0.691

High

300168

KRA56
Keratin-associated protein 5-6

4

0

High-throughput

0.675

High

246207

MABP1
Mitogen-activated protein kinase-binding protein 1

3

13

High-throughput

0.675

High

300110

KRA59
Keratin-associated protein 5-9

3

20

High-throughput

0.675

High

300131

KR108
Keratin-associated protein 10-8

3

20

High-throughput

0.675

High

300132

KR109
Keratin-associated protein 10-9

3

20

High-throughput

0.675

High

300228

KRA92
Keratin-associated protein 9-2

3

20

High-throughput

0.675

High

300229

KR411
Keratin-associated protein 4-11

3

20

High-throughput

0.675

High

300240

TRI36
E3 ubiquitin-protein ligase TRIM36

3

20

High-throughput

0.675

High

300144

TRAF1
TNF receptor-associated factor 1

2

5

High-throughput

0.651

High

180456

PLS1
Phospholipid scramblase 1

2

1

High-throughput

0.646

High

285009

EED
Polycomb protein EED

2

18

Small-scale

0.631

High

62079

KLRG2
Killer cell lectin-like receptor subfamily G member 2

4

3

High-throughput

0.630

High

300109

RIR1
Ribonucleoside-diphosphate reductase large subunit

2

1

High-throughput

0.628

High

300180

NAA40
N-alpha-acetyltransferase 40

2

2

High-throughput

0.628

High

300234

KPCD2
Serine/threonine-protein kinase D2

2

8

High-throughput

0.625

High

300207

GMCL1
Germ cell-less protein-like 1

2

3

High-throughput

0.625

High

300140

EWS
RNA-binding protein EWS

1

13

High-throughput

0.618

High

300239

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.618

High

300217

M3K3
Mitogen-activated protein kinase kinase kinase 3

2

4

High-throughput

0.613

High

300130

KR105
Keratin-associated protein 10-5

2

20

High-throughput

0.611

High

300249

NDOR1
NADPH-dependent diflavin oxidoreductase 1

2

1

Small-scale

0.611

High

300117

NTF4
Neurotrophin-4

2

1

High-throughput

0.606

High

300124

MAP11
Methionine aminopeptidase 1

2

1

High-throughput

0.606

High

300127

KR123
Keratin-associated protein 12-3

2

2

High-throughput

0.606

High

300136

IRX6
Iroquois-class homeodomain protein IRX-6

2

1

High-throughput

0.606

High

300152

ZN124
Zinc finger protein 124

2

10

High-throughput

0.606

High

300167

KR511
Keratin-associated protein 5-11

2

20

High-throughput

0.606

High

300170

KRA53
Keratin-associated protein 5-3

2

20

High-throughput

0.606

High

300171

ZN774
Zinc finger protein 774

2

9

High-throughput

0.606

High

300199

LNX1
E3 ubiquitin-protein ligase LNX

2

5

High-throughput

0.606

High

300206

SMRC1
SWI/SNF complex subunit SMARCC1

2

1

High-throughput

0.606

High

300226

KRA98
Keratin-associated protein 9-8

2

20

High-throughput

0.606

High

300227

KRA93
Keratin-associated protein 9-3

2

20

High-throughput

0.606

High

300231

KRA45
Keratin-associated protein 4-5

2

20

High-throughput

0.606

High

300232

KRA44
Keratin-associated protein 4-4

2

20

High-throughput

0.606

High

300245

RCOR3
REST corepressor 3

2

1

High-throughput

0.606

High

300251

ZN490
Zinc finger protein 490

2

7

High-throughput

0.606

High

300141

KPCT
Protein kinase C theta type

1

6

Small-scale

0.586

High

240323

PRKN
E3 ubiquitin-protein ligase parkin

2

11

High-throughput

0.584

High

300076

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

2

16

Small-scale

0.584

High

300128

KR101
Keratin-associated protein 10-1

2

20

High-throughput

0.584

High

300162

LCE2D
Late cornified envelope protein 2D

2

1

High-throughput

0.583

High

300246

GBG13

2

0

High-throughput

0.580

High

300090

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

20

High-throughput

0.576

High

300190

DND1
Dead end protein homolog 1

1

1

High-throughput

0.575

High

300075

KRT38
Keratin, type I cuticular Ha8

1

6

High-throughput

0.573

High

300081

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

3

High-throughput

0.573

High

300098

ITF2
Transcription factor 4

1

1

High-throughput

0.573

High

300145

CBLB
E3 ubiquitin-protein ligase CBL-B

1

2

High-throughput

0.573

High

300147

IKZF1
DNA-binding protein Ikaros

1

5

High-throughput

0.573

High

300151

K1H1
Keratin, type I cuticular Ha1

1

6

High-throughput

0.573

High

300172

ZN544
Zinc finger protein 544

1

5

High-throughput

0.573

High

300179

NT2NA
Notch homolog 2 N-terminal-like protein A

1

5

High-throughput

0.573

High

300195

ZBT44
Zinc finger and BTB domain-containing protein 44

1

8

High-throughput

0.573

High

300222

SOX7
Transcription factor SOX-7

1

1

High-throughput

0.573

High

300223

ZN426
Zinc finger protein 426

1

7

High-throughput

0.573

High

300233

KRA42
Keratin-associated protein 4-2

1

20

High-throughput

0.573

High

300099

GATA1
Erythroid transcription factor

1

1

High-throughput

0.560

High

300120

BCL6
B-cell lymphoma 6 protein

1

8

High-throughput

0.560

High

300185

KRA13
Keratin-associated protein 1-3

1

20

High-throughput

0.560

High

300200

CCHCR
Coiled-coil alpha-helical rod protein 1

1

6

High-throughput

0.560

High

300211

PKH4B
Pleckstrin homology domain-containing family G member 4B

1

1

High-throughput

0.560

High

300216

MDFI
MyoD family inhibitor

1

1

High-throughput

0.560

High

300112

CO8A1
Collagen alpha-1(VIII) chain

2

10

High-throughput

0.553

High

300137

ATL3
ADAMTS-like protein 3

2

2

High-throughput

0.553

High

300159

GT253
Inactive glycosyltransferase 25 family member 3

2

7

High-throughput

0.553

High

300236

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

2

1

High-throughput

0.553

High

300122

GUAA
GMP synthase [glutamine-hydrolyzing]

1

2

Small-scale

0.552

High

300105

VCAM1
Vascular cell adhesion protein 1

2

2

High-throughput

0.549

High

300155

UGPA
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.549

High

300213

ALKB3
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3

1

0

High-throughput

0.549

High

300215

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.549

High

300247

CGBP1
CGG triplet repeat-binding protein 1

1

0

High-throughput

0.549

High

300080

NADK
NAD kinase

1

3

High-throughput

0.541

High

300142

TLE5
TLE family member 5

1

0

High-throughput

0.536

High

213742

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

6

High-throughput

0.536

High

300087

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

3

High-throughput

0.536

High

300096

SRC
Proto-oncogene tyrosine-protein kinase Src

1

3

High-throughput

0.536

High

300138

CBX1
Chromobox protein homolog 1

1

1

High-throughput

0.536

High

300148

KCC1A
Calcium/calmodulin-dependent protein kinase type 1

1

4

High-throughput

0.536

High

300186

AHNK2
Protein AHNAK2

1

1

High-throughput

0.536

High

300193

KCD17
BTB/POZ domain-containing protein KCTD17

1

10

High-throughput

0.536

High

300197

DAAF1
Dynein axonemal assembly factor 1

1

6

High-throughput

0.536

High

300219

SH3G1
Endophilin-A2

1

2

High-throughput

0.536

High

300235

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

1

High-throughput

0.536

High

300244

ST32B
Serine/threonine-protein kinase 32B

1

5

High-throughput

0.536

High

300133

KR10B
Keratin-associated protein 10-11

1

20

High-throughput

0.529

High

300187

TRI42
Tripartite motif-containing protein 42

1

20

High-throughput

0.523

High

300205

PCSK5
Proprotein convertase subtilisin/kexin type 5

1

6

High-throughput

0.523

High

300210

NOE3
Noelin-3

1

1

High-throughput

0.523

High

300243

F118A
Protein FAM118A

1

1

High-throughput

0.523

High

300253

ZN148
Zinc finger protein 148

1

9

High-throughput

0.523

High

300178

F10C1
Protein FRA10AC1

1

0

High-throughput

0.518

High

300202

HEXD
Hexosaminidase D

1

0

High-throughput

0.518

High

300169

KRA54
Keratin-associated protein 5-4

1

20

High-throughput

0.515

High

300181

ZN410
Zinc finger protein 410

1

6

High-throughput

0.515

High

300182

CD20B
Cell division cycle protein 20 homolog B

1

14

High-throughput

0.515

High

300230

KRA47
Keratin-associated protein 4-7

1

20

High-throughput

0.515

High

271386

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.513

High

300104

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

1

0

High-throughput

0.513

High

300113

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.513

High

300123

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2

1

0

High-throughput

0.513

High

300150

CND2
Condensin complex subunit 2

1

0

High-throughput

0.513

High

300161

SYT6
Synaptotagmin-6

1

0

High-throughput

0.513

High

300255

EMC9
ER membrane protein complex subunit 9

1

0

High-throughput

0.513

High

300191

LNX2
Ligand of Numb protein X 2

1

5

High-throughput

0.512

High

300101

ZNF23
Zinc finger protein 23

1

8

High-throughput

0.508

High

300153

MK06
Mitogen-activated protein kinase 6

1

9

High-throughput

0.508

High

300082

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

11

High-throughput

0.494

High

300176

ATL4
ADAMTS-like protein 4

1

3

High-throughput

0.494

High

300160

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.493

High

300088

FINC
Fibronectin

1

4

High-throughput

0.489

High

300103

EGLN
Endoglin

1

1

High-throughput

0.489

High

300196

PDZD8
PDZ domain-containing protein 8

1

2

High-throughput

0.489

High

300225

TX101
Testis-expressed protein 101

1

1

High-throughput

0.489

High

300129

KR103
Keratin-associated protein 10-3

1

20

High-throughput

0.481

High

300184

KR131
Keratin-associated protein 13-1

1

1

High-throughput

0.481

High

137889

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

7

Small-scale

0.479

High

259233

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.479

High

300078

RECQ4
ATP-dependent DNA helicase Q4

1

5

High-throughput

0.479

High

300091

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

300095

BIP
Endoplasmic reticulum chaperone BiP

1

16

High-throughput

0.479

High

300097

ITA4
Integrin alpha-4

1

1

High-throughput

0.479

High

300102

CEBPB
CCAAT/enhancer-binding protein beta

1

13

High-throughput

0.479

High

300106

RAB5A
Ras-related protein Rab-5A

1

3

High-throughput

0.479

High

300115

PML
Protein PML

1

12

High-throughput

0.479

High

300119

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

300126

TERA
Transitional endoplasmic reticulum ATPase

1

13

High-throughput

0.479

High

300135

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

7

High-throughput

0.479

High

300143

EP300
Histone acetyltransferase p300

1

8

High-throughput

0.479

High

300149

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

5

High-throughput

0.479

High

300163

TET5C
Terminal nucleotidyltransferase 5C

1

2

High-throughput

0.479

High

300177

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

300194

SERB1
SERPINE1 mRNA-binding protein 1

1

5

High-throughput

0.479

High

300203

TOPB1
DNA topoisomerase 2-binding protein 1

1

5

High-throughput

0.479

High

300204

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

11

High-throughput

0.479

High

300212

LMTK3
Serine/threonine-protein kinase LMTK3

1

20

High-throughput

0.479

High

300214

MMS19
MMS19 nucleotide excision repair protein homolog

1

2

High-throughput

0.479

High

300218

DUS9
Dual specificity protein phosphatase 9

1

5

High-throughput

0.479

High

300238

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.479

High

300248

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

300250

TNIK
TRAF2 and NCK-interacting protein kinase

1

1

High-throughput

0.479

High

300256

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

1

High-throughput

0.479

High

300157

Q53SE7
Germ cell-less homolog 1

1

3

High-throughput

0.470

High

300173

Q6P9E2
RECK protein

1

1

High-throughput

0.470

High

300208

LRIG1
Leucine-rich repeats and immunoglobulin-like domains protein 1

1

4

Small-scale

0.464

High

300209

Z512B
Zinc finger protein 512B

1

7

High-throughput

0.464

High

300084

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

300125

EMP2
Epithelial membrane protein 2

1

0

High-throughput

0.458

High

142257

PEX7
Peroxisomal targeting signal 2 receptor

1

16

High-throughput

0.445

High

300089

PRIO
Major prion protein

1

3

High-throughput

0.445

High

300094

TAU
Microtubule-associated protein tau

1

7

High-throughput

0.445

High

300139

E2F1
Transcription factor E2F1

1

2

High-throughput

0.445

High

300164

A16L1
Autophagy-related protein 16-1

1

19

High-throughput

0.445

High

300166

PKHA7
Pleckstrin homology domain-containing family A member 7

1

16

High-throughput

0.445

High

300189

ULK2
Serine/threonine-protein kinase ULK2

1

4

High-throughput

0.445

High

300201

TGFA1
Transforming growth factor-beta receptor-associated protein 1

1

7

High-throughput

0.445

High

300242

DDX28
Probable ATP-dependent RNA helicase DDX28

1

2

High-throughput

0.445

High

300252

GAB2
GRB2-associated-binding protein 2

1

4

High-throughput

0.445

High

300083

RECK
Reversion-inducing cysteine-rich protein with Kazal motifs

1

1

High-throughput

0.439

High

104982

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

217631

TGON2
Trans-Golgi network integral membrane protein 2

1

10

High-throughput

0.437

High

300086

AGR2
Anterior gradient protein 2 homolog

1

6

High-throughput

0.437

High

300092

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

2

High-throughput

0.437

High

300107

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

3

High-throughput

0.437

High

300118

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

300254

AAR2
Protein AAR2 homolog

1

6

High-throughput

0.437

High

210228

PHF1
PHD finger protein 1

1

0

High-throughput

0.426

High

261024

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.426

High

300100

ANFB
Natriuretic peptides B

1

0

High-throughput

0.426

High

300134

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

0

High-throughput

0.426

High

300158

TAF7L
Transcription initiation factor TFIID subunit 7-like

1

0

High-throughput

0.426

High

300258

PCDG9
Protocadherin gamma-A9

1

0

High-throughput

0.426

High

300121

CEBPA
CCAAT/enhancer-binding protein alpha

1

13

High-throughput

0.408

High

75554

B3KSW4
Regulator of G protein signaling 20

1

1

High-throughput

0.407

High

300079

VENTX
Homeobox protein VENTX

1

1

High-throughput

0.407

High

300093

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.407

High

300111

CD27
CD27 antigen

1

3

High-throughput

0.407

High

300192

TTC9C
Tetratricopeptide repeat protein 9C

1

4

High-throughput

0.407

High

300241

ITM2C
Integral membrane protein 2C

1

2

High-throughput

0.407

High

300175

MOXD1
DBH-like monooxygenase protein 1

4

0

High-throughput

0.368

High

300154

CAH9
Carbonic anhydrase 9

3

0

High-throughput

0.351

High

300183

TMM25
Transmembrane protein 25

2

0

High-throughput

0.337

High

300085

TCL1B
T-cell leukemia/lymphoma protein 1B

2

0

High-throughput

0.316

High

300108

IL10
Interleukin-10

2

0

High-throughput

0.316

High

300198

KLDC9
Kelch domain-containing protein 9

2

0

High-throughput

0.316

High

300224

STRA6
Receptor for retinol uptake STRA6

2

0

High-throughput

0.316

High

300188

IHO1
Interactor of HORMAD1 protein 1

1

0

High-throughput

0.292

High

750

A0A087WZT3
BOLA2-SMG1P6 readthrough

1

0

High-throughput

0.268

Low

300221

HEPH
Hephaestin

1

0

High-throughput

0.268

Low

300146

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low

300174

S27A1
Long-chain fatty acid transport protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025