Protein: OMA1
Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Metalloprotease-related protein 1) (MPRP-1) (Overlapping with the m-AAA protease 1 homolog)

Gene: OMA1
Organism: Homo sapiens
Interactions: 138
UniProt ID: Q96E52

Gene Ontology (top 5):
GO:0002024 - diet induced thermogenesis
GO:0004222 - metalloendopeptidase activity
GO:0005743 - mitochondrial inner membrane
GO:0005758 - mitochondrial intermembrane space
GO:0006006 - glucose metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1160165

S39A4
Zinc transporter ZIP4

3

0

High-throughput

0.638

High

325314

AIFM1
Apoptosis-inducing factor 1, mitochondrial

3

0

High-throughput

0.613

High

1289298

TOR3A
Torsin-3A

3

1

High-throughput

0.609

High

50448

SYCE3
Synaptonemal complex central element protein 3

2

0

High-throughput

0.602

High

154627

TPP1
Tripeptidyl-peptidase 1

2

0

High-throughput

0.602

High

1289290

MIC26
MICOS complex subunit MIC26

2

1

High-throughput

0.584

High

1289292

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

2

1

High-throughput

0.574

High

525590

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

2

0

High-throughput

0.559

High

1289300

SFXN1
Sideroflexin-1

2

0

High-throughput

0.559

High

235405

ADCY9
Adenylate cyclase type 9

1

1

High-throughput

0.536

High

768550

ADCY8
Adenylate cyclase type 8

1

1

High-throughput

0.536

High

199602

B4GT5
Beta-1,4-galactosyltransferase 5

1

0

High-throughput

0.513

High

213980

KRT86
Keratin, type II cuticular Hb6

1

1

High-throughput

0.489

High

600821

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

1

High-throughput

0.489

High

1055219

KRT81
Keratin, type II cuticular Hb1

1

1

High-throughput

0.489

High

1267988

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

1

High-throughput

0.489

High

224640

TIM8A
Mitochondrial import inner membrane translocase subunit Tim8 A

1

1

High-throughput

0.479

High

274598

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

2

High-throughput

0.479

High

1122759

OCAD2
OCIA domain-containing protein 2

1

1

High-throughput

0.479

High

1135288

ATD3B
ATPase family AAA domain-containing protein 3B

1

1

High-throughput

0.479

High

1154109

SCMC2
Mitochondrial adenyl nucleotide antiporter SLC25A25

1

2

High-throughput

0.479

High

1156215

SCMC1
Mitochondrial adenyl nucleotide antiporter SLC25A24

1

2

High-throughput

0.479

High

1166772

MIC27
MICOS complex subunit MIC27

1

1

High-throughput

0.479

High

1223666

MICU2
Calcium uptake protein 2, mitochondrial

1

2

High-throughput

0.479

High

1289283

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.479

High

1289284

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.479

High

1289285

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

1

High-throughput

0.479

High

1289286

MICU1
Calcium uptake protein 1, mitochondrial

1

2

High-throughput

0.479

High

1289288

MIC25
MICOS complex subunit MIC25

1

1

High-throughput

0.479

High

1289293

CLPB
Mitochondrial disaggregase

1

1

High-throughput

0.479

High

1289295

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

3

High-throughput

0.479

High

1289306

ATD3A
ATPase family AAA domain-containing protein 3A

1

1

High-throughput

0.479

High

1289308

MIC19
MICOS complex subunit MIC19

1

1

High-throughput

0.479

High

1289319

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

1

High-throughput

0.479

High

1289321

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

1

High-throughput

0.479

High

750

A0A087WYV9
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial

1

0

High-throughput

0.458

High

118399

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.458

High

210576

NDUB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

1

0

High-throughput

0.458

High

231142

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

0

High-throughput

0.458

High

259116

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

1

0

High-throughput

0.458

High

276862

SCO1
Protein SCO1 homolog, mitochondrial

1

0

High-throughput

0.458

High

297083

TOM70
Mitochondrial import receptor subunit TOM70

1

0

High-throughput

0.458

High

307417

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.458

High

330342

NDUBA
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

1

0

High-throughput

0.458

High

371180

NU4M
NADH-ubiquinone oxidoreductase chain 4

1

0

High-throughput

0.458

High

441138

CY1
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.458

High

454036

COX6C
Cytochrome c oxidase subunit 6C

1

0

High-throughput

0.458

High

495742

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

0

High-throughput

0.458

High

519812

KCRU
Creatine kinase U-type, mitochondrial

1

0

High-throughput

0.458

High

584044

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.458

High

594946

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.458

High

658118

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

0

High-throughput

0.458

High

736181

HEM6
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial

1

0

High-throughput

0.458

High

795039

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

831920

CEBPD
CCAAT/enhancer-binding protein delta

1

0

Small-scale

0.458

High

851954

NDUA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

1

0

High-throughput

0.458

High

864244

CCHL
Holocytochrome c-type synthase

1

0

High-throughput

0.458

High

873060

KAD2
Adenylate kinase 2, mitochondrial

1

0

High-throughput

0.458

High

879919

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

1

0

High-throughput

0.458

High

949146

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.458

High

958499

CYC
Cytochrome c

1

0

High-throughput

0.458

High

1052375

NUCG
Endonuclease G, mitochondrial

1

0

High-throughput

0.458

High

1088593

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

1118919

MIX23
Protein MIX23

1

0

High-throughput

0.458

High

1150463

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

1

0

High-throughput

0.458

High

1162915

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

0

High-throughput

0.458

High

1183187

COX15
Heme A synthase COX15

1

0

High-throughput

0.458

High

1216917

T126B
Complex I assembly factor TMEM126B, mitochondrial

1

0

High-throughput

0.458

High

1283197

F162A
Protein FAM162A

1

0

High-throughput

0.458

High

1285114

TM186
Transmembrane protein 186

1

0

High-throughput

0.458

High

1285850

COA7
Cytochrome c oxidase assembly factor 7

1

0

High-throughput

0.458

High

1289287

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.458

High

1289296

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

1289299

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1289302

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.458

High

1289304

MITOS
Mitochondrial potassium channel ATP-binding subunit

1

0

High-throughput

0.458

High

1289305

DJC11
DnaJ homolog subfamily C member 11

1

0

High-throughput

0.458

High

1289312

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.458

High

1289316

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

0

High-throughput

0.458

High

1289320

SAM50
Sorting and assembly machinery component 50 homolog

1

0

High-throughput

0.458

High

1289323

NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

1

0

High-throughput

0.458

High

264605

MTX2
Metaxin-2

1

1

High-throughput

0.437

High

627327

MCM3
DNA replication licensing factor MCM3

1

1

High-throughput

0.437

High

1037145

MTX1
Metaxin-1

1

1

High-throughput

0.437

High

1289307

OCAD1
OCIA domain-containing protein 1

1

1

High-throughput

0.437

High

1289318

COA3
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial

1

0

Small-scale

0.426

High

699612

IFNA8
Interferon alpha-8

3

0

High-throughput

0.347

High

801631

S15A1
Solute carrier family 15 member 1

2

0

High-throughput

0.328

High

847754

P2RX1
P2X purinoceptor 1

2

0

High-throughput

0.328

High

1103575

S4A8
Electroneutral sodium bicarbonate exchanger 1

2

0

High-throughput

0.328

High

1116844

GXLT1
Glucoside xylosyltransferase 1

2

0

High-throughput

0.328

High

1147812

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

2

0

High-throughput

0.328

High

1157171

IIGP5
Interferon-inducible GTPase 5

2

0

High-throughput

0.328

High

1203293

AMGO3
Amphoterin-induced protein 3

2

0

High-throughput

0.328

High

1289291

CNPD1
Protein CNPPD1

2

0

High-throughput

0.328

High

1289294

SIL1
Nucleotide exchange factor SIL1

2

0

High-throughput

0.328

High

1289309

SCN3B
Sodium channel regulatory subunit beta-3

2

0

High-throughput

0.328

High

1289314

FA8A1
Protein FAM8A1

2

0

High-throughput

0.328

High

1289322

5MP1
eIF5-mimic protein 1

2

0

High-throughput

0.328

High

68083

HIDE1
Protein HIDE1

1

0

High-throughput

0.279

Low

206592

S26A4
Pendrin

1

0

High-throughput

0.279

Low

393471

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

0

High-throughput

0.279

Low

644621

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

0

High-throughput

0.279

Low

750674

INGR2
Interferon gamma receptor 2

1

0

High-throughput

0.279

Low

781096

OPRX
Nociceptin receptor

1

0

High-throughput

0.279

Low

814298

GLR
Glucagon receptor

1

0

High-throughput

0.279

Low

958347

AT11A
Phospholipid-transporting ATPase IH

1

0

High-throughput

0.279

Low

960704

FANCC
Fanconi anemia group C protein

1

0

High-throughput

0.279

Low

997434

VAC14
Protein VAC14 homolog

1

0

High-throughput

0.279

Low

1089470

CC142
Coiled-coil domain-containing protein 142

1

0

High-throughput

0.279

Low

1109144

KRA61
Keratin-associated protein 6-1

1

0

High-throughput

0.279

Low

1109680

TBC25
TBC1 domain family member 25

1

0

High-throughput

0.279

Low

1110419

KR197
Keratin-associated protein 19-7

1

0

High-throughput

0.279

Low

1132861

ODAD2
Outer dynein arm-docking complex subunit 2

1

0

High-throughput

0.279

Low

1189985

KCNKI
Potassium channel subfamily K member 18

1

0

High-throughput

0.279

Low

1239945

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.279

Low

1284417

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

0

High-throughput

0.279

Low

1287556

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.279

Low

1289282

SAAL1
Protein SAAL1

1

0

High-throughput

0.279

Low

1289297

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.279

Low

1289310

SC5A4
Probable glucose sensor protein SLC5A4

1

0

High-throughput

0.279

Low

1289313

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.279

Low

1289317

UST
Uronyl 2-sulfotransferase

1

0

High-throughput

0.279

Low

393314

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.269

Low

528014

RINI
Ribonuclease inhibitor

1

0

High-throughput

0.249

Low

556649

CBR1
Carbonyl reductase [NADPH] 1

1

0

High-throughput

0.249

Low

941291

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1136070

ATPF1
ATP synthase mitochondrial F1 complex assembly factor 1

1

0

High-throughput

0.249

Low

1173911

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

1

0

High-throughput

0.249

Low

1191364

ADCK2
Uncharacterized aarF domain-containing protein kinase 2

1

0

High-throughput

0.249

Low

1236952

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

1286173

F136A
Protein FAM136A

1

0

High-throughput

0.249

Low

1289289

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.249

Low

1289301

PLRKT
Plasminogen receptor

1

0

High-throughput

0.249

Low

1289303

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.249

Low

1289311

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

0

High-throughput

0.249

Low

348857

RASN
GTPase NRas

1

0

High-throughput

0.232

Low

1289315

DYH17
Dynein axonemal heavy chain 17

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024