HitPredict

Interactor 1: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1

Interactor 2: HNRPD (Q14103)
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)
Gene: HNRNPD

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29656893
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042162 - telomeric DNA binding GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1972 Hs			1 355
+	Hs
		162029 TP53B_HUMAN (1-1972): 0: 766: 100.00		HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63
+	Hs
		1019104 TP53B_HUMAN (1-1972): 0: 766: 100.00		ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89
+	Hs
		609830 TP53B_HUMAN (1-1972): 0: 766: 100.00		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		807720 MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		162098 TITIN_HUMAN (6-1527): 2.77e-31: 137: 9.47		HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63
+	Hs
		1264791 TITIN_HUMAN (6-1527): 2.77e-31: 137: 9.47		ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89
+	Hs
		1031405 TITIN_HUMAN (6-1527): 2.77e-31: 137: 9.47		PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52
+	Hs
		1056955 MDC1_HUMAN (10-773): 2.05e-23: 111: 10.33		ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89
+	Hs
		516609 TITIN_HUMAN (6-1527): 2.77e-31: 137: 9.47		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Hs
		965152 ANK2_HUMAN (3-1685): 1.72e-50: 200: 9.45		PABP3_HUMAN (172-267): 5.97e-16: 80.9: 16.50
+	Hs
		609973 TITIN_HUMAN (6-1527): 2.77e-31: 137: 9.47		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		516749 SRRM2_HUMAN (18-1418): 1.61e-14: 82.2: 9.78		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Hs
		610114 SRRM2_HUMAN (18-1418): 1.61e-14: 82.2: 9.78		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		1104165 TITIN_HUMAN (6-1527): 2.77e-31: 137: 9.47		RA1L2_HUMAN (46-167): 1.11e-13: 72.9: 27.87
+	Hs
		453712 SRRM2_HUMAN (18-1418): 1.61e-14: 82.2: 9.78		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83