Protein: GSTP1
Glutathione S-transferase P (EC 2.5.1.18) (GST class-pi) (GSTP1-1)

Gene: GSTP1
Organism: Homo sapiens
Interactions: 170
UniProt ID: P09211

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000302 - response to reactive oxygen species
GO:0002674 - negative regulation of acute inflammatory response
GO:0004364 - glutathione transferase activity
GO:0004602 - glutathione peroxidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

479750

GSTP1
Glutathione S-transferase P

2

18

Small-scale

0.755

High

479777

MK08
Mitogen-activated protein kinase 8

4

8

Small-scale

0.702

High

240549

PRKN
E3 ubiquitin-protein ligase parkin

4

2

High-throughput

0.686

High

479788

KR107
Keratin-associated protein 10-7

3

4

High-throughput

0.675

High

479822

K1H1
Keratin, type I cuticular Ha1

3

3

High-throughput

0.675

High

479851

APBP2
Amyloid protein-binding protein 2

3

2

High-throughput

0.675

High

479838

NT2NA
Notch homolog 2 N-terminal-like protein A

2

1

High-throughput

0.633

High

479805

TRAF2
TNF receptor-associated factor 2

2

3

Small-scale

0.628

High

479809

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

2

High-throughput

0.618

High

300286

KRT34
Keratin, type I cuticular Ha4

2

3

High-throughput

0.606

High

479768

TGM1
Protein-glutamine gamma-glutamyltransferase K

2

1

High-throughput

0.606

High

479803

KRA11
Keratin-associated protein 1-1

2

4

High-throughput

0.606

High

479818

KT33B
Keratin, type I cuticular Ha3-II

2

3

High-throughput

0.606

High

479842

KRA13
Keratin-associated protein 1-3

2

4

High-throughput

0.606

High

479861

CAR10
Caspase recruitment domain-containing protein 10

2

1

High-throughput

0.606

High

479863

KRA33
Keratin-associated protein 3-3

2

1

High-throughput

0.606

High

479864

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.606

High

479881

LR2BP
LRP2-binding protein

2

2

High-throughput

0.606

High

362638

EGFR
Epidermal growth factor receptor

2

0

Small-scale

0.603

High

479815

CUL3
Cullin-3

2

3

High-throughput

0.601

High

479797

FANCC
Fanconi anemia group C protein

2

1

Small-scale

0.586

High

70093

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.580

High

479780

HXA1
Homeobox protein Hox-A1

2

0

High-throughput

0.580

High

479795

KRT83
Keratin, type II cuticular Hb3

2

0

High-throughput

0.580

High

479825

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.580

High

479827

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

0

High-throughput

0.580

High

479829

FHL5
Four and a half LIM domains protein 5

2

0

High-throughput

0.580

High

479835

ATL4
ADAMTS-like protein 4

2

0

High-throughput

0.580

High

479846

ZN655
Zinc finger protein 655

2

0

High-throughput

0.580

High

479789

KR109
Keratin-associated protein 10-9

1

4

High-throughput

0.573

High

479793

RAC1
Ras-related C3 botulinum toxin substrate 1

2

1

High-throughput

0.571

High

479845

SH2D3
SH2 domain-containing protein 3C

2

4

High-throughput

0.571

High

479858

ZBT18
Zinc finger and BTB domain-containing protein 18

2

1

Small-scale

0.571

High

370984

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

388935

FINC
Fibronectin

2

0

Small-scale

0.559

High

479763

VCAM1
Vascular cell adhesion protein 1

2

0

High-throughput

0.547

High

479886

SHLB1
Endophilin-B1

1

1

High-throughput

0.541

High

328623

VAMP5
Vesicle-associated membrane protein 5

1

1

High-throughput

0.536

High

385382

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.536

High

479751

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.536

High

479755

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.536

High

479758

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

1

High-throughput

0.536

High

479775

RBMX
RNA-binding motif protein, X chromosome

1

2

High-throughput

0.536

High

479799

ACY1
Aminoacylase-1

1

1

High-throughput

0.536

High

479802

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

High-throughput

0.536

High

479807

FOXD4
Forkhead box protein D4

1

4

High-throughput

0.536

High

479814

CUL2
Cullin-2

1

3

High-throughput

0.536

High

479834

FXL19
F-box/LRR-repeat protein 19

1

1

High-throughput

0.536

High

479843

CDKL3
Cyclin-dependent kinase-like 3

1

2

High-throughput

0.536

High

479853

CSN5
COP9 signalosome complex subunit 5

1

3

High-throughput

0.536

High

479857

SRPK1
SRSF protein kinase 1

1

1

High-throughput

0.536

High

479884

DNJB4
DnaJ homolog subfamily B member 4

1

1

High-throughput

0.536

High

479764

PTN
Pleiotrophin

1

0

High-throughput

0.518

High

479878

PNO1
RNA-binding protein PNO1

1

0

High-throughput

0.518

High

479754

NT2NC
Notch homolog 2 N-terminal-like protein C

1

1

High-throughput

0.515

High

135029

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

0

High-throughput

0.513

High

187261

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

0

High-throughput

0.513

High

282657

E2F6
Transcription factor E2F6

1

0

High-throughput

0.513

High

361073

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

479774

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.513

High

479794

TYB10
Thymosin beta-10

1

0

High-throughput

0.513

High

479796

TXN4A
Thioredoxin-like protein 4A

1

0

High-throughput

0.513

High

479817

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

479831

Z518A
Zinc finger protein 518A

1

0

High-throughput

0.513

High

479833

JADE1
Protein Jade-1

1

0

High-throughput

0.513

High

479866

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.513

High

185371

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

3

High-throughput

0.501

High

479771

PRDX6
Peroxiredoxin-6

1

3

Small-scale

0.501

High

479873

GORS2
Golgi reassembly-stacking protein 2

1

1

High-throughput

0.489

High

479776

MLH1
DNA mismatch repair protein Mlh1

1

0

Small-scale

0.486

High

479787

KR103
Keratin-associated protein 10-3

1

4

High-throughput

0.481

High

169910

AURKA
Aurora kinase A

1

2

High-throughput

0.479

High

259335

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

302336

RNF8
E3 ubiquitin-protein ligase RNF8

1

1

High-throughput

0.479

High

319323

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

324443

HEXI1
Protein HEXIM1

1

3

High-throughput

0.479

High

328219

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

1

1

High-throughput

0.479

High

352873

AGR2
Anterior gradient protein 2 homolog

1

2

Small-scale

0.479

High

425268

ISG15
Ubiquitin-like protein ISG15

1

3

High-throughput

0.479

High

479753

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

Small-scale

0.479

High

479759

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

479761

CXA1
Gap junction alpha-1 protein

1

1

Small-scale

0.479

High

479762

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.479

High

479766

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

1

Small-scale

0.479

High

479767

CBL
E3 ubiquitin-protein ligase CBL

1

1

High-throughput

0.479

High

479770

MK01
Mitogen-activated protein kinase 1

1

1

Small-scale

0.479

High

479772

CDC27
Cell division cycle protein 27 homolog

1

3

Small-scale

0.479

High

479786

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

3

High-throughput

0.479

High

479791

UBC12
NEDD8-conjugating enzyme Ubc12

1

1

High-throughput

0.479

High

479800

GABP1
GA-binding protein subunit beta-1

1

3

High-throughput

0.479

High

479801

PRDX1
Peroxiredoxin-1

1

3

Small-scale

0.479

High

479806

FOXC1
Forkhead box protein C1

1

4

High-throughput

0.479

High

479808

TRAF3
TNF receptor-associated factor 3

1

4

Small-scale

0.479

High

479810

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

5

Small-scale

0.479

High

479811

SKP2
S-phase kinase-associated protein 2

1

2

Small-scale

0.479

High

479813

SQSTM
Sequestosome-1

1

3

High-throughput

0.479

High

479819

NBR1
Next to BRCA1 gene 1 protein

1

1

High-throughput

0.479

High

479824

MK14
Mitogen-activated protein kinase 14

1

6

Small-scale

0.479

High

479826

LARP7
La-related protein 7

1

1

High-throughput

0.479

High

479828

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.479

High

479830

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

479837

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

479840

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

6

Small-scale

0.479

High

479841

GOLI
E3 ubiquitin-protein ligase RNF130

1

1

High-throughput

0.479

High

479844

RPTOR
Regulatory-associated protein of mTOR

1

1

High-throughput

0.479

High

479848

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.479

High

479849

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.479

High

479850

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

479852

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

479859

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

4

Small-scale

0.479

High

479870

ATG5
Autophagy protein 5

1

1

High-throughput

0.479

High

479875

ANLN
Anillin

1

2

High-throughput

0.479

High

479879

FXL12
F-box/LRR-repeat protein 12

1

2

Small-scale

0.479

High

479882

HDAC6
Protein deacetylase HDAC6

1

2

High-throughput

0.479

High

479883

DUX4
Double homeobox protein 4

1

1

High-throughput

0.479

High

468

NBPFJ
NBPF family member NBPF19

1

0

High-throughput

0.460

High

479872

SFR19
Splicing factor, arginine/serine-rich 19

1

0

High-throughput

0.460

High

176019

KDM6B
Lysine-specific demethylase 6B

1

0

Small-scale

0.458

High

262001

NBN
Nibrin

1

0

Small-scale

0.458

High

411227

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

479752

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

479757

ITA4
Integrin alpha-4

1

0

High-throughput

0.458

High

479760

IL7RA
Interleukin-7 receptor subunit alpha

1

0

High-throughput

0.458

High

479769

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

479773

FUS
RNA-binding protein FUS

1

0

High-throughput

0.458

High

479778

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

479779

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.458

High

479782

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

479783

DNLI4
DNA ligase 4

1

0

High-throughput

0.458

High

479784

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.458

High

479798

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

High-throughput

0.458

High

479804

B2CL1
Bcl-2-like protein 1

1

0

High-throughput

0.458

High

479812

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

479816

DX39B
Spliceosome RNA helicase DDX39B

1

0

High-throughput

0.458

High

479820

CUL7
Cullin-7

1

0

High-throughput

0.458

High

479821

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

479823

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

479839

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

479855

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

479856

RANB9
Ran-binding protein 9

1

0

Small-scale

0.458

High

479860

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

479865

TRIM6
Tripartite motif-containing protein 6

1

0

Small-scale

0.458

High

479868

ARL6
ADP-ribosylation factor-like protein 6

1

0

High-throughput

0.458

High

479874

NGB
Neuroglobin

1

0

High-throughput

0.458

High

479876

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

479885

NINL
Ninein-like protein

1

0

High-throughput

0.458

High

479887

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

479862

RNF26
E3 ubiquitin-protein ligase RNF26

1

1

Small-scale

0.457

High

327751

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

7

High-throughput

0.445

High

344071

PTBP3
Polypyrimidine tract-binding protein 3

1

1

High-throughput

0.445

High

429176

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

479756

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

479785

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.445

High

479790

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

7

High-throughput

0.445

High

479792

GRB2
Growth factor receptor-bound protein 2

1

2

High-throughput

0.445

High

479867

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

7

High-throughput

0.445

High

479869

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

7

High-throughput

0.445

High

479871

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

7

High-throughput

0.445

High

105168

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

900

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.426

High

479854

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

479781

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.408

High

116691

H9ZYI9
GA binding protein transcription factor beta subunit 1 transcript variant gamma-2

1

2

High-throughput

0.407

High

479832

Q6FGG4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

1

1

High-throughput

0.407

High

479877

FBX8
F-box only protein 8

1

0

Small-scale

0.301

High

479880

BAHC1
BAH and coiled-coil domain-containing protein 1

1

0

High-throughput

0.279

Low

479847

DC4L2
DDB1- and CUL4-associated factor 4-like protein 2

1

0

Small-scale

0.249

Low

479765

EPHA1
Ephrin type-A receptor 1

1

0

High-throughput

0.238

Low

479836

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025