HitPredict

Interactor 1: ILF3 (Q12906)
Interleukin enhancer-binding factor 3 (Double-stranded RNA-binding protein 76) (DRBP76) (M-phase phosphoprotein 4) (MPP4) (Nuclear factor associated with dsRNA) (NFAR) (Nuclear factor of activated T-cells 90 kDa) (NF-AT-90) (Translational control protein 80) (TCP80)
Gene: ILF3

Interactor 2: WRN (Q14191)
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 5.6.2.4) (DNA 3'-5' helicase WRN)]
Gene: WRN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Helicase_C~dsrm
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 894 Hs			1 1432
+	Hs
		877269 DSRAD_HUMAN (341-681): 5.37e-44: 175: 20.00		WRN_HUMAN (1-1432): 0: 1103: 100.00
+	Hs
		944777 RED1_HUMAN (337-610): 6.93e-37: 150: 34.29		WRN_HUMAN (1-1432): 0: 1103: 100.00
+	Hs
		294772 ILF3_HUMAN (1-894): 0: 687: 100.00		RECQ4_HUMAN (530-878): 2.42e-118: 402: 29.95
+	Hs
		134005 ILF3_HUMAN (1-894): 0: 687: 100.00		DDX3X_HUMAN (354-901): 6.63e-119: 389: 14.85
+	Hs
		1019858 ILF3_HUMAN (1-894): 0: 687: 100.00		DDX17_HUMAN (469-955): 1.98e-117: 387: 16.54
+	Hs
		571421 ILF3_HUMAN (1-894): 0: 687: 100.00		DDX5_HUMAN (469-892): 8.41e-112: 368: 16.96
+	Hs
		295138 ZFR_HUMAN (5-363): 1.94e-145: 459: 51.81		RECQ4_HUMAN (530-878): 2.42e-118: 402: 29.95
+	Hs
		571553 ZFR_HUMAN (5-363): 1.94e-145: 459: 51.81		DDX5_HUMAN (469-892): 8.41e-112: 368: 16.96
+	Hs
		294771 ILF2_HUMAN (1-361): 4.06e-116: 361: 23.59		RECQ4_HUMAN (530-878): 2.42e-118: 402: 29.95
+	Hs
		134004 ILF2_HUMAN (1-361): 4.06e-116: 361: 23.59		DDX3X_HUMAN (354-901): 6.63e-119: 389: 14.85
+	Hs
		322302 STAU1_HUMAN (341-766): 8.78e-37: 148: 18.88		RECQ1_HUMAN (461-1117): 3.09e-152: 478: 26.11
+	Hs
		294586 DSRAD_HUMAN (341-681): 5.37e-44: 175: 20.00		RECQ4_HUMAN (530-878): 2.42e-118: 402: 29.95
+	Hs
		867570 RED1_HUMAN (337-610): 6.93e-37: 150: 34.29		BLM_HUMAN (221-1158): 8.03e-120: 410: 21.16
+	Hs
		944841 RED1_HUMAN (337-610): 6.93e-37: 150: 34.29		DDX46_HUMAN (278-1201): 6e-120: 402: 12.60
+	Hs
		294236 STAU1_HUMAN (341-766): 8.78e-37: 148: 18.88		RECQ4_HUMAN (530-878): 2.42e-118: 402: 29.95
+	Hs
		133809 STAU1_HUMAN (341-766): 8.78e-37: 148: 18.88		DDX3X_HUMAN (354-901): 6.63e-119: 389: 14.85
+	Hs
		322951 STAU1_HUMAN (341-766): 8.78e-37: 148: 18.88		DDX17_HUMAN (469-955): 1.98e-117: 387: 16.54
+	Hs
		181692 RED1_HUMAN (337-610): 6.93e-37: 150: 34.29		DDX3Y_HUMAN (354-926): 1.19e-116: 383: 14.19
+	Hs
		571400 RED1_HUMAN (337-610): 6.93e-37: 150: 34.29		DDX5_HUMAN (469-892): 8.41e-112: 368: 16.96
+	Hs
		322157 STAU1_HUMAN (341-766): 8.78e-37: 148: 18.88		DDX5_HUMAN (469-892): 8.41e-112: 368: 16.96