HitPredict

Interactor 1: EPS8 (Q12929)
Epidermal growth factor receptor kinase substrate 8
Gene: EPS8

Interactor 2: BAIP2 (Q9UQB8)
BAR/IMD domain-containing adapter protein 2 (Brain-specific angiogenesis inhibitor 1-associated protein 2) (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53)
Gene: BAIAP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 25416956, 16189514, 25814554, 28514442, 33961781, 26186194, 15289329, 19564905, 24584464, unassigned1126, 24076653
Identification Methods two hybrid, affinity chromatography technology, pull down, anti bait coimmunoprecipitation, cosedimentation in solution, fluorescent resonance energy transfer, molecular sieving, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation and 2 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SH3_1~SH3_2
Common GO terms GO:0005886 - plasma membrane
GO:0008360 - regulation of cell shape
GO:0051017 - actin filament bundle assembly
GO:0051764 - actin crosslink formation
GO:0070062 - extracellular exosome
and 1 others

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Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 822
Hs

1 552
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Last updated: 15 Jul 2024