Interactor 1: TRAF2 (Q12933)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)
Gene: TRAF2
Interactor 2: TRAF2 (Q12933)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)
Gene: TRAF2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.98 | 1.00 | 0.991 |
The method score is based on:
Property | Details |
---|---|
Experiments | 20447407, 25416956, 23007157, 16189514, 26390021, 30561431, 32296183, 8702708, 10411888, 9020361, 33539883, 34070875, 36185580, 37081115, 12591926, 19810754, 20577214, 15383523, 20385093, 11181075 and 7 others
more... |
Identification Methods | x-ray crystallography, two hybrid, enzymatic study, pull down, affinity chromatography technology, fluorescent resonance energy transfer, anti tag coimmunoprecipitation, two hybrid array, virotrap, two hybrid prey pooling approach and 3 others
more... |
Interaction Type | association, direct interaction, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | TRAF_BIRC3_bd~TRAF_BIRC3_bd |
Common GO terms | GO:0000151 - ubiquitin ligase complex GO:0002637 - regulation of immunoglobulin production GO:0002726 - positive regulation of T cell cytokine production GO:0002947 - tumor necrosis factor receptor superfamily complex GO:0004842 - ubiquitin-protein transferase activity and 52 others more... |
Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024