Protein: 1433E
14-3-3 protein epsilon (Suppressor of Ras1 3-9)

Gene: 1433E, 14-3-3epsilon
Organism: Drosophila melanogaster
Interactions: 169
UniProt ID: P92177

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0001223 - transcription coactivator binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005694 - chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

709527

1433Z
14-3-3 protein zeta

4

18

Small-scale

0.891

High

1019855

YAP1
Transcriptional coactivator yorkie

5

14

Small-scale

0.703

High

1019970

IRS1
Insulin receptor substrate 1

4

5

Small-scale

0.686

High

541190

KRAF1
Raf homolog serine/threonine-protein kinase Raf

1

16

High-throughput

0.618

High

1019882

FOXO
Forkhead box protein O

2

6

High-throughput

0.611

High

1019899

Q9VCC9
LD23779p

2

16

High-throughput

0.611

High

1014297

UBX
Homeotic protein ultrabithorax

2

0

Small-scale

0.610

High

120292

M9PD17
Gigas, isoform B

2

11

High-throughput

0.584

High

1019924

RHEB
GTP-binding protein Rheb homolog

2

3

Small-scale

0.584

High

1019900

Q9VD02
GH14779p

1

7

High-throughput

0.575

High

195020

O16043
Anon1A4

2

1

High-throughput

0.571

High

476924

NDKA
Nucleoside diphosphate kinase

2

1

High-throughput

0.571

High

649022

ANX10
Annexin B10

2

2

High-throughput

0.571

High

929468

PDI
Protein disulfide-isomerase

2

4

High-throughput

0.571

High

1019853

NLP
Nucleoplasmin-like protein

2

2

High-throughput

0.571

High

1019939

Q9VTY2
Uncharacterized protein, isoform A

2

2

High-throughput

0.571

High

1019951

Q9VX75
Bazooka, isoform A

1

10

Small-scale

0.568

High

1019849

Q0KIF1
Plexin A, isoform B

1

2

Small-scale

0.552

High

356324

O97102
Small ubiquitin-related modifier

2

0

Small-scale

0.547

High

1019885

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

2

0

High-throughput

0.547

High

1019931

EXOC2
Exocyst complex component 2

1

1

High-throughput

0.541

High

1019892

SIN1
Stress-activated map kinase-interacting protein 1

1

1

High-throughput

0.536

High

1019912

Q9VHP9
Centromeric protein-C, isoform A

2

1

Small-scale

0.533

High

1019852

RPR
Cell death protein rpr

1

0

High-throughput

0.518

High

1019950

Q9VWS3
Rab11 interacting protein, isoform A

1

12

Small-scale

0.512

High

756444

ECR
Ecdysone receptor

1

3

Small-scale

0.501

High

1019949

Q9VWJ6
FI03615p

1

2

High-throughput

0.489

High

94942

E1JGN0
MAP/microtubule affinity-regulating kinase 3

1

20

High-throughput

0.481

High

1019865

Q7KM03
cyclin-dependent kinase

1

10

High-throughput

0.481

High

56260

A1ZA18
Kinesin heavy chain 73, isoform A

1

12

Small-scale

0.479

High

578058

ENO
Enolase

1

1

High-throughput

0.479

High

583665

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

8

Small-scale

0.479

High

633059

NCD
Protein claret segregational

1

5

Small-scale

0.479

High

712335

CALR
Calreticulin

1

2

High-throughput

0.479

High

723780

DLG1
Disks large 1 tumor suppressor protein

1

5

Small-scale

0.479

High

1019846

GRAP
Growth factor receptor-bound protein 2

1

9

High-throughput

0.479

High

1019847

Q0KHR3
Bazooka, isoform B

1

12

Small-scale

0.479

High

1019850

DSOR1
Dual specificity mitogen-activated protein kinase kinase dSOR1

1

13

High-throughput

0.479

High

1019856

Q6NN29
Nuclear fallout, isoform E

1

9

Small-scale

0.479

High

1019868

Q7KNQ9
Connector enhancer of KSR protein CNK

1

15

High-throughput

0.479

High

1019881

Q95TN8
Serine/threonine-protein kinase greatwall

1

20

Small-scale

0.479

High

1019898

CRERF
Protein CREBRF homolog

1

1

Small-scale

0.479

High

1019907

TCTP
Translationally-controlled tumor protein homolog

1

2

Small-scale

0.479

High

1019915

Q9VJX3
B4, isoform A

1

1

High-throughput

0.479

High

1019934

Q9VR61
non-specific serine/threonine protein kinase

1

11

High-throughput

0.479

High

1019938

NDE1
Nuclear distribution protein nudE homolog

1

7

Small-scale

0.479

High

1019942

PYRG
CTP synthase

1

1

High-throughput

0.479

High

1019956

TNG2
Transport and Golgi organization protein 2

1

1

High-throughput

0.479

High

53221

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

5

High-throughput

0.457

High

120639

M9PE01
cyclin-dependent kinase

1

10

High-throughput

0.457

High

1019871

CCDCX
Coiled-coil domain-containing protein CG32809

1

1

High-throughput

0.457

High

1019963

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

12

High-throughput

0.457

High

1019971

Q9XYW6
E3 ubiquitin-protein ligase CHIP

1

5

High-throughput

0.457

High

53990

A1Z892
1-Cys peroxiredoxin

1

3

High-throughput

0.445

High

57537

A1ZB71
Glutathione S transferase E6

1

2

High-throughput

0.445

High

57759

A1ZB77
Uncharacterized protein, isoform J

1

1

High-throughput

0.445

High

121203

ALDR
Aldo-keto reductase 1B

1

2

High-throughput

0.445

High

357485

INO1
Inositol-3-phosphate synthase

1

3

High-throughput

0.445

High

556655

PSA1
Proteasome subunit alpha type-1

1

2

High-throughput

0.445

High

633121

MPIP
M-phase inducer phosphatase

1

10

High-throughput

0.445

High

871608

FKB12
Peptidyl-prolyl cis-trans isomerase Fkbp12

1

3

High-throughput

0.445

High

1019577

TRXR1
Thioredoxin reductase 1, mitochondrial

1

3

High-throughput

0.445

High

1019845

PGK
Phosphoglycerate kinase

1

2

High-throughput

0.445

High

1019851

PCL
Polycomb protein Pcl

1

4

Small-scale

0.445

High

1019857

Q76NR6
Regucalcin

1

3

High-throughput

0.445

High

1019859

Q7JVH6
LD24696p

1

2

High-throughput

0.445

High

1019861

Q7JX87
1-Cys peroxiredoxin

1

3

High-throughput

0.445

High

1019866

TERA
Transitional endoplasmic reticulum ATPase TER94

1

9

High-throughput

0.445

High

1019873

Q8IQZ7
FI19014p1

1

7

High-throughput

0.445

High

1019876

Q8MT58
Carnosine dipeptidase 2, isoform A

1

2

High-throughput

0.445

High

1019878

Q8T0L3
E1 ubiquitin-activating enzyme

1

1

High-throughput

0.445

High

1019891

THIO2
Thioredoxin-2

1

1

High-throughput

0.445

High

1019894

Q9VAC4
GEO09167p1

1

2

High-throughput

0.445

High

1019895

Q9VAN7
Phosphoglycerate mutase

1

4

High-throughput

0.445

High

1019902

Q9VEB1
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.445

High

1019909

TEBPH
Cytosolic Prostaglandin E synthase

1

1

High-throughput

0.445

High

1019910

JHD1
JmjC domain-containing histone demethylation protein 1

1

5

High-throughput

0.445

High

1019911

Q9VHN7
transketolase

1

2

High-throughput

0.445

High

1019917

Q9VKW5
Prolyl endopeptidase

1

1

High-throughput

0.445

High

1019918

EF1D
Probable elongation factor 1-delta

1

3

High-throughput

0.445

High

1019920

Q9VL70
HL08109p

1

4

High-throughput

0.445

High

1019921

FKB59
FK506-binding protein 59

1

3

High-throughput

0.445

High

1019922

AK200
A-kinase anchor protein 200

1

3

High-throughput

0.445

High

1019928

Q9VPN5
Stress-induced-phosphoprotein 1

1

6

High-throughput

0.445

High

1019929

Q9VPX6
Adenylyl cyclase-associated protein

1

1

High-throughput

0.445

High

1019935

Q9VRD6
NTF2-related export protein

1

3

High-throughput

0.445

High

1019936

Q9VRL1
GEO06356p1

1

2

High-throughput

0.445

High

1019937

Q9VSL2
Glutathione S transferase O3

1

1

High-throughput

0.445

High

1019940

Q9VU35
10 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.445

High

1019941

Q9VUC1
Hsc70Cb, isoform A

1

7

High-throughput

0.445

High

1019944

Q9VV77
Polycomb group RING finger protein 3

1

5

High-throughput

0.445

High

1019948

Q9VW83
Gigas, isoform A

1

11

High-throughput

0.445

High

1019954

CLIC
Chloride intracellular channel Clic

1

4

High-throughput

0.445

High

1019960

Q9W022
GEO01508p1

1

2

High-throughput

0.445

High

1019961

Q9W0H8
Reticulocalbin-3

1

5

High-throughput

0.445

High

1019964

Q9W227
Peptidyl-prolyl cis-trans isomerase

1

7

High-throughput

0.445

High

1019966

CISY
Probable citrate synthase, mitochondrial

1

3

High-throughput

0.445

High

1019967

WUHO
tRNA

1

6

High-throughput

0.445

High

1019972

Q9XYZ9
Glutathione S transferase E12, isoform A

1

3

High-throughput

0.445

High

1019973

Q9XZ57
Eb1, isoform E

1

1

High-throughput

0.445

High

1019974

PSA6
Proteasome subunit alpha type-6

1

3

High-throughput

0.445

High

1019848

Q0KHR4
FI21203p1

1

0

High-throughput

0.438

High

1019860

Q7JVK8
GEO08987p1

1

0

High-throughput

0.438

High

1019875

INDRA
Zinc finger protein indra

1

0

High-throughput

0.438

High

1019888

Q9V3S3
Protamine A, isoform A

1

0

High-throughput

0.438

High

1019896

Q9VBJ6
Uncharacterized protein

1

0

High-throughput

0.438

High

1019916

Q9VKR2
Replication termination factor 2

1

0

High-throughput

0.438

High

1019955

Q9VYA4
Ribonuclease H2 subunit B

1

0

High-throughput

0.438

High

119571

M9PAY7
Pi3K21B, isoform C

1

10

High-throughput

0.437

High

120759

M9PE30
Transgelin

1

7

High-throughput

0.437

High

1019913

NESD
Protein nessun dorma

1

2

Small-scale

0.437

High

1019957

Q9VYR1
Regucalcin

1

3

High-throughput

0.437

High

1019958

Q9VYT3
FI23714p1

1

3

Small-scale

0.437

High

197747

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.426

High

357274

O97428
Ciboulot, isoform A

1

0

High-throughput

0.426

High

928947

DOD
Putative peptidyl-prolyl cis-trans isomerase dodo

1

0

High-throughput

0.426

High

930119

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.426

High

1019867

Q7KN99
Phosphopantothenoylcysteine synthetase, isoform A

1

0

High-throughput

0.426

High

1019870

Q7KTW5
Inositol-1-monophosphatase

1

0

High-throughput

0.426

High

1019872

Q8INK3
Fatty acid-binding protein, muscle

1

0

High-throughput

0.426

High

1019874

Q8IRD3
Glutathione peroxidase

1

0

High-throughput

0.426

High

1019877

Q8STA5
Histidine triad nucleotide binding protein 1, isoform A

1

0

High-throughput

0.426

High

1019879

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.426

High

1019880

FAXC
Failed axon connections

1

0

High-throughput

0.426

High

1019883

IF5A
Eukaryotic translation initiation factor 5A

1

0

High-throughput

0.426

High

1019884

JUPIT
Microtubule-associated protein Jupiter

1

0

High-throughput

0.426

High

1019887

Q9V3I1
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

0

High-throughput

0.426

High

1019889

SPC25
Kinetochore protein Spc25

1

0

High-throughput

0.426

High

1019890

Q9V3V9
Endonuclease G inhibitor, isoform A

1

0

High-throughput

0.426

High

1019893

Q9V9U3
LD45254p

1

0

High-throughput

0.426

High

1019919

Q9VL68
Enoyl-CoA delta isomerase 1, mitochondrial

1

0

High-throughput

0.426

High

1019930

BACC
Bacchus

1

0

High-throughput

0.426

High

1019945

Y9705
Cold shock domain-containing protein CG9705

1

0

High-throughput

0.426

High

1019946

Q9VW59
Rho GDP-dissociation inhibitor 3

1

0

High-throughput

0.426

High

1019953

Q9VXQ3
Diphosphomevalonate decarboxylase

1

0

High-throughput

0.426

High

1019962

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

High-throughput

0.426

High

1019965

Q9W3Y3
Calcyclin-binding protein

1

0

High-throughput

0.426

High

1019968

Q9W457
Serine hydroxymethyltransferase

1

0

High-throughput

0.426

High

1019975

PURA
Adenylosuccinate synthetase

1

0

High-throughput

0.426

High

95579

E2QDA1
FI15228p1

1

1

High-throughput

0.417

High

86472

B9EQV3
Endoplasmic reticulum transmembrane protein

1

1

High-throughput

0.407

High

304611

RS21
Small ribosomal subunit protein eS21

1

1

High-throughput

0.407

High

1019854

Q3YMU0
Protein disulfide-isomerase

1

4

High-throughput

0.407

High

1019858

Q7JR96
SD19533p

1

3

High-throughput

0.407

High

1019869

RS15B
Small ribosomal subunit protein uS8B

1

3

High-throughput

0.407

High

1019906

Q9VGK3
peptidylprolyl isomerase

1

3

High-throughput

0.407

High

1019959

Q9VZI1
Transgelin

1

9

High-throughput

0.407

High

1019864

Q7K9Q9
PAR-1 ser/thr kinase N2

1

1

High-throughput

0.381

High

1019863

Q7K4P0
LD30408p

2

0

High-throughput

0.310

High

1019927

Q9VP84
IP06402p

2

0

High-throughput

0.300

High

1019943

Q9VV55
GH08429p

2

0

High-throughput

0.298

High

1019914

Q9VJ98
GH05617p

1

0

High-throughput

0.265

Low

92314

D3DMW4
MIP17104p

1

0

Small-scale

0.249

Low

1019908

Q9VGV7
CG4570 protein

1

0

High-throughput

0.249

Low

1019901

Q9VDK2
GH15831p

1

0

High-throughput

0.238

Low

1019903

Q9VFT9
FI15725p1

1

0

High-throughput

0.238

Low

1019904

Q9VG03
GH08448p

1

0

High-throughput

0.238

Low

1019925

Q9VNI5
LD10772p

1

0

High-throughput

0.238

Low

1019932

IFT57
Intraflagellar transport protein 57 homolog

1

0

High-throughput

0.238

Low

1019933

Q9VQW5
GEO10314p1

1

0

High-throughput

0.238

Low

1019862

Q7K2K2
FI04612p

1

0

High-throughput

0.232

Low

1019886

CP2B
Cardio acceleratory peptide 2b

1

0

High-throughput

0.232

Low

1019897

Q9VBT1
CHK kinase-like domain-containing protein

1

0

High-throughput

0.232

Low

1019905

Q9VG33
Sulfurtransferase

1

0

High-throughput

0.232

Low

1019923

Q9VNB2
RE42193p

1

0

High-throughput

0.232

Low

1019926

Q9VP52
GH24315p

1

0

High-throughput

0.232

Low

1019947

Q9VW70
FI21813p1

1

0

High-throughput

0.232

Low

1019952

DHB4
Peroxisomal multifunctional enzyme type 2

1

0

High-throughput

0.232

Low

1019969

Q9W478
RE43153p

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025