Interactor 1: TRAF2 (Q12933)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3)
Gene: TRAF2

Interactor 2: TANK (Q92844)
TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF)
Gene: TANK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.762

The method score is based on:

Property Details
Experiments 28514442, 28155233, 30561431, 8710854, 10759890, 33961781, 20562859, 21903422, 23007157, 14743216, 10581243, 12005438, 21988832
Identification Methods affinity chromatography technology, unspecified method, two hybrid, pull down, tandem affinity purification, anti tag coimmunoprecipitation, virotrap
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0031625 - ubiquitin protein ligase binding
GO:0060090 - molecular adaptor activity
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 501
Hs

1 425
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024