HitPredict

Interactor 1: FOXL1 (Q12952)
Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead-related transcription factor 7) (FREAC-7)
Gene: FOXL1

Interactor 2: ZFHX4 (Q86UP3)
Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4)
Gene: ZFHX4

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	25609649, 35140242
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 345 Hs			1 3567
+	Hs
		1199927 FOXB1_HUMAN (38-315): 6.26e-51: 173: 29.14		ZFHX4_HUMAN (1-3567): 0: 1729: 95.83
+	Hs
		1021229 FOXI1_HUMAN (6-234): 5.98e-50: 172: 35.02		ZFHX4_HUMAN (1-3567): 0: 1729: 95.83
+	Hs
		1021292 FOXL1_HUMAN (1-345): 1.46e-108: 322: 100.00		ZFHX3_HUMAN (1632-3519): 2.55e-12: 75.8: 8.58
+	Hs
		822694 FOXA2_HUMAN (7-320): 8.22e-53: 182: 29.13		LHX1_HUMAN (2539-2624): 7.55e-09: 63.2: 42.86