HitPredict

Interactor 1: CSTF3 (Q12996)
Cleavage stimulation factor subunit 3 (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (CstF-77)
Gene: CSTF3

Interactor 2: RNPS1 (Q15287)
RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)
Gene: RNPS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 717 Hs			1 305
+	Sc
		628773 RNA14_YEAST (8-557): 1.71e-86: 288: 23.89		NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46
+	Sc
		763253 PRP39_YEAST (56-503): 2.04e-57: 207: 14.26		NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46
+	Sc
		977593 PRP42_YEAST (24-453): 1.89e-50: 186: 15.21		NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46
+	Dm
		54167 SYF1_DROME (15-568): 3.85e-39: 157: 11.89		PPIE_DROME (157-291): 2.07e-31: 120: 18.52
+	Ce
		954283 P91175_CAEEL (34-604): 1.86e-41: 164: 11.40		Q9U2S6_CAEEL (156-263): 5.51e-20: 90.4: 20.37
+	Hs
		1070619 CRNL1_HUMAN (69-574): 5.03e-29: 125: 15.20		RNPS1_HUMAN (1-234): 2e-34: 128: 100.00
+	Hs
		1318165 CRNL1_HUMAN (69-574): 5.03e-29: 125: 15.20		PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73
+	Hs
		1063203 SART3_HUMAN (3-278): 3.26e-14: 78.5: 14.73		SART3_HUMAN (2-302): 1.67e-38: 146: 16.32
+	Hs
		174907 OGT1_HUMAN (17-302): 6.94e-18: 90.4: 13.24		RNPS1_HUMAN (1-234): 2e-34: 128: 100.00
+	Hs
		1070651 SYF1_HUMAN (5-399): 1.04e-17: 89.7: 11.63		RNPS1_HUMAN (1-234): 2e-34: 128: 100.00
+	Hs
		1336499 SYF1_HUMAN (5-399): 1.04e-17: 89.7: 11.63		PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73
+	Hs
		174461 OGT1_HUMAN (17-302): 6.94e-18: 90.4: 13.24		RFOX2_HUMAN (44-274): 2.32e-31: 122: 13.25
+	Hs
		1063207 SART3_HUMAN (3-278): 3.26e-14: 78.5: 14.73		RNPS1_HUMAN (1-234): 2e-34: 128: 100.00
+	Sc
		978483 SYF1_YEAST (14-509): 4.69e-14: 78.1: 13.60		NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46
+	Hs
		300152 PRP6_HUMAN (7-294): 2.02e-09: 63.1: 8.30		RNPS1_HUMAN (1-234): 2e-34: 128: 100.00
+	Hs
		300288 PRP6_HUMAN (7-294): 2.02e-09: 63.1: 8.30		PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73
+	Hs
		174583 OGT1_HUMAN (17-302): 6.94e-18: 90.4: 13.24		PABP1_HUMAN (65-252): 1.33e-21: 96.9: 16.32
+	Sc
		996591 CLF1_YEAST (3-257): 6.46e-09: 61.2: 15.59		NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46
+	Hs
		174849 OGT1_HUMAN (17-302): 6.94e-18: 90.4: 13.24		PABP4_HUMAN (153-248): 4.98e-19: 89.2: 27.08
+	Hs
		300087 PRP6_HUMAN (7-294): 2.02e-09: 63.1: 8.30		NCBP2_HUMAN (128-271): 1.08e-30: 114: 18.06