Protein: FBLN5
Fibulin-5 (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50)

Gene: FBLN5
Organism: Homo sapiens
Interactions: 177
UniProt ID: Q9UBX5

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005178 - integrin binding
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1324543

LTBP4
Latent-transforming growth factor beta-binding protein 4

2

18

High-throughput

0.776

High

1458870

EGFL7
Epidermal growth factor-like protein 7

2

20

High-throughput

0.776

High

1132146

LTBP2
Latent-transforming growth factor beta-binding protein 2

2

19

Small-scale

0.737

High

351616

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

20

Small-scale

0.724

High

136993

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

19

High-throughput

0.691

High

654563

FBLN1
Fibulin-1

1

19

High-throughput

0.691

High

1132067

LTBP1
Latent-transforming growth factor beta-binding protein 1

1

20

High-throughput

0.691

High

1458874

ST14
Suppressor of tumorigenicity 14 protein

1

11

High-throughput

0.691

High

1277954

NUFP2
FMR1-interacting protein NUFIP2

5

9

High-throughput

0.655

High

772299

FBN1
Fibrillin-1 [Cleaved into: Asprosin]

1

18

Small-scale

0.647

High

1458868

FBLN5
Fibulin-5

1

19

Small-scale

0.647

High

1063923

LOXL1
Lysyl oxidase homolog 1

2

9

Small-scale

0.636

High

1276071

ZN550
Zinc finger protein 550

2

20

High-throughput

0.628

High

702201

LYOX
Protein-lysine 6-oxidase

2

9

Small-scale

0.576

High

1312083

DJC10
DnaJ homolog subfamily C member 10

2

14

High-throughput

0.574

High

1331474

ZFP41
Zinc finger protein 41 homolog

2

20

High-throughput

0.574

High

1437007

ZN408
Zinc finger protein 408

2

20

High-throughput

0.574

High

1447581

ZN331
Zinc finger protein 331

2

20

High-throughput

0.574

High

733229

OTX1
Homeobox protein OTX1

1

5

High-throughput

0.573

High

894223

MEOX2
Homeobox protein MOX-2

1

6

High-throughput

0.573

High

584626

ELN
Elastin

1

9

Small-scale

0.561

High

272524

OBSL1
Obscurin-like protein 1

2

7

High-throughput

0.549

High

316116

RECQ4
ATP-dependent DNA helicase Q4

2

5

High-throughput

0.549

High

1231201

TRI68
E3 ubiquitin-protein ligase TRIM68

2

2

High-throughput

0.549

High

1273088

ZN627
Zinc finger protein 627

2

20

High-throughput

0.549

High

1385022

ZN669
Zinc finger protein 669

2

20

High-throughput

0.549

High

1435821

MET17
Ribosome assembly protein METTL17, mitochondrial

2

1

High-throughput

0.549

High

1435931

ZN696
Zinc finger protein 696

2

20

High-throughput

0.549

High

885440

HXA1
Homeobox protein Hox-A1

1

18

High-throughput

0.541

High

129819

CBX4
E3 SUMO-protein ligase CBX4

1

2

High-throughput

0.536

High

183308

LAMA5
Laminin subunit alpha-5

1

19

High-throughput

0.536

High

271338

ZBED4
Zinc finger BED domain-containing protein 4

1

1

High-throughput

0.536

High

285507

EED
Polycomb protein EED

1

6

High-throughput

0.536

High

335407

GDF11
Growth/differentiation factor 11

1

12

High-throughput

0.536

High

376916

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

12

High-throughput

0.536

High

405628

HRG
Histidine-rich glycoprotein

1

4

High-throughput

0.536

High

430461

JUN
Transcription factor Jun

1

5

High-throughput

0.536

High

574011

HXB3
Homeobox protein Hox-B3

1

9

High-throughput

0.536

High

601985

ZNF8
Zinc finger protein 8

1

20

High-throughput

0.536

High

605277

ATF7
Cyclic AMP-dependent transcription factor ATF-7

1

6

High-throughput

0.536

High

662328

PAX3
Paired box protein Pax-3

1

3

High-throughput

0.536

High

765969

BMI1
Polycomb complex protein BMI-1

1

4

High-throughput

0.536

High

766131

PCGF2
Polycomb group RING finger protein 2

1

3

High-throughput

0.536

High

862728

UTRN
Utrophin

1

6

High-throughput

0.536

High

913736

ZN136
Zinc finger protein 136

1

20

High-throughput

0.536

High

937662

FOXG1
Forkhead box protein G1

1

7

High-throughput

0.536

High

1039829

CREB5
Cyclic AMP-responsive element-binding protein 5

1

7

High-throughput

0.536

High

1086136

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

3

High-throughput

0.536

High

1091060

FOXF1
Forkhead box protein F1

1

9

High-throughput

0.536

High

1091087

FOXF2
Forkhead box protein F2

1

9

High-throughput

0.536

High

1238494

ZN746
Zinc finger protein 746

1

20

High-throughput

0.536

High

1249690

IGFL3
Insulin growth factor-like family member 3

1

5

High-throughput

0.536

High

1253990

RBPS2
RNA-binding protein with multiple splicing 2

1

1

High-throughput

0.536

High

1286806

KAISO
Transcriptional regulator Kaiso

1

20

High-throughput

0.536

High

1307720

CILP2
Cartilage intermediate layer protein 2

1

12

High-throughput

0.536

High

1311047

SULF2
Extracellular sulfatase Sulf-2

1

5

High-throughput

0.536

High

1335869

ZBT34
Zinc finger and BTB domain-containing protein 34

1

20

High-throughput

0.536

High

1355970

NET5
Netrin-5

1

20

High-throughput

0.536

High

1394780

HIC2
Hypermethylated in cancer 2 protein

1

20

High-throughput

0.536

High

1417548

EMIL2
EMILIN-2

1

18

High-throughput

0.536

High

1421243

ZN407
Zinc finger protein 407

1

20

High-throughput

0.536

High

1433628

SMOC1
SPARC-related modular calcium-binding protein 1

1

7

High-throughput

0.536

High

1438132

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

1

20

High-throughput

0.536

High

1438401

TAF9B
Transcription initiation factor TFIID subunit 9B

1

2

High-throughput

0.536

High

1439229

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

5

High-throughput

0.536

High

1449494

EMIL3
EMILIN-3

1

16

High-throughput

0.536

High

1451208

BCD1
Box C/D snoRNA protein 1

1

1

High-throughput

0.536

High

1454039

SENP1
Sentrin-specific protease 1

1

5

High-throughput

0.536

High

1458875

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

1

High-throughput

0.536

High

1151101

PCH2
Pachytene checkpoint protein 2 homolog

1

3

High-throughput

0.523

High

650468

FGFR3
Fibroblast growth factor receptor 3

1

16

High-throughput

0.515

High

705591

GRN
Progranulin

1

2

High-throughput

0.515

High

1279784

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

7

High-throughput

0.515

High

163186

CHK1
Serine/threonine-protein kinase Chk1

1

0

High-throughput

0.513

High

1361789

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.513

High

928360

ATN1
Atrophin-1

1

14

High-throughput

0.508

High

1217773

GFI1B
Zinc finger protein Gfi-1b

1

20

High-throughput

0.508

High

301744

WFS1
Wolframin

1

0

High-throughput

0.493

High

60200

ZN320
Zinc finger protein 320

1

20

High-throughput

0.489

High

63784

KRBA1
Protein KRBA1

1

2

High-throughput

0.489

High

134401

RPOM
DNA-directed RNA polymerase, mitochondrial

1

1

High-throughput

0.489

High

159022

ZN195
Zinc finger protein 195

1

20

High-throughput

0.489

High

246173

KIF1B
Kinesin-like protein KIF1B

1

2

High-throughput

0.489

High

276008

DUS11
RNA/RNP complex-1-interacting phosphatase

1

4

High-throughput

0.489

High

276741

ZN253
Zinc finger protein 253

1

20

High-throughput

0.489

High

278186

ZN737
Zinc finger protein 737

1

20

High-throughput

0.489

High

282906

Z324A
Zinc finger protein 324A

1

20

High-throughput

0.489

High

316328

RECQ5
ATP-dependent DNA helicase Q5

1

5

High-throughput

0.489

High

336239

ZIC2
Zinc finger protein ZIC 2

1

20

High-throughput

0.489

High

340052

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

2

High-throughput

0.489

High

510062

ZN865
Zinc finger protein 865

1

18

High-throughput

0.489

High

667496

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

High-throughput

0.489

High

725163

HXC9
Homeobox protein Hox-C9

1

4

High-throughput

0.489

High

1017506

FOXK1
Forkhead box protein K1

1

9

High-throughput

0.489

High

1022689

ZXDB
Zinc finger X-linked protein ZXDB

1

20

High-throughput

0.489

High

1036616

ZNF45
Zinc finger protein 45

1

13

High-throughput

0.489

High

1044437

ZNF92
Zinc finger protein 92

1

20

High-throughput

0.489

High

1116095

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

9

High-throughput

0.489

High

1124562

MAP7
Ensconsin

1

8

High-throughput

0.489

High

1128625

ZN235
Zinc finger protein 235

1

10

High-throughput

0.489

High

1128693

ZN460
Zinc finger protein 460

1

20

High-throughput

0.489

High

1128714

ZN273
Zinc finger protein 273

1

20

High-throughput

0.489

High

1135150

CUL7
Cullin-7

1

1

High-throughput

0.489

High

1138957

R3HD1
R3H domain-containing protein 1

1

2

High-throughput

0.489

High

1156090

ZNF77
Zinc finger protein 77

1

20

High-throughput

0.489

High

1159277

ZNF74
Zinc finger protein 74

1

20

High-throughput

0.489

High

1206564

PRC2B
Protein PRRC2B

1

4

High-throughput

0.489

High

1213096

RHG21
Rho GTPase-activating protein 21

1

2

High-throughput

0.489

High

1230737

Z518A
Zinc finger protein 518A

1

20

High-throughput

0.489

High

1231886

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

1

High-throughput

0.489

High

1232072

TTLL5
Tubulin polyglutamylase TTLL5

1

2

High-throughput

0.489

High

1252786

RN111
E3 ubiquitin-protein ligase Arkadia

1

2

High-throughput

0.489

High

1253091

ZN620
Zinc finger protein 620

1

20

High-throughput

0.489

High

1271973

ZN765
Zinc finger protein 765

1

20

High-throughput

0.489

High

1294893

KI18B
Kinesin-like protein KIF18B

1

3

High-throughput

0.489

High

1312510

PHC2
Polyhomeotic-like protein 2

1

2

High-throughput

0.489

High

1315167

ZN440
Zinc finger protein 440

1

20

High-throughput

0.489

High

1322368

ZN444
Zinc finger protein 444

1

20

High-throughput

0.489

High

1325531

FBXW8
F-box/WD repeat-containing protein 8

1

6

High-throughput

0.489

High

1335958

ZBT44
Zinc finger and BTB domain-containing protein 44

1

20

High-throughput

0.489

High

1336938

PHC3
Polyhomeotic-like protein 3

1

11

High-throughput

0.489

High

1338778

ARI1B
AT-rich interactive domain-containing protein 1B

1

3

High-throughput

0.489

High

1359613

ATX2L
Ataxin-2-like protein

1

2

High-throughput

0.489

High

1365996

APBP2
Amyloid protein-binding protein 2

1

2

High-throughput

0.489

High

1385314

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

20

High-throughput

0.489

High

1392750

ZN764
Zinc finger protein 764

1

20

High-throughput

0.489

High

1392795

P121A
Nuclear envelope pore membrane protein POM 121

1

3

High-throughput

0.489

High

1393264

SENP5
Sentrin-specific protease 5

1

5

High-throughput

0.489

High

1410284

KLDC3
Kelch domain-containing protein 3

1

4

High-throughput

0.489

High

1415063

ZN747
Zinc finger protein 747

1

20

High-throughput

0.489

High

1415699

TR61B
tRNA

1

1

High-throughput

0.489

High

1420657

SETD5
Histone-lysine N-methyltransferase SETD5

1

3

High-throughput

0.489

High

1428661

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

High-throughput

0.489

High

1435585

PEAK1
Inactive tyrosine-protein kinase PEAK1

1

4

High-throughput

0.489

High

1436252

ZN430
Zinc finger protein 430

1

20

High-throughput

0.489

High

1445961

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

2

High-throughput

0.489

High

1448523

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.489

High

1449747

ZBT40
Zinc finger and BTB domain-containing protein 40

1

20

High-throughput

0.489

High

1454288

ZN492
Zinc finger protein 492

1

20

High-throughput

0.489

High

1458869

ZN282
Zinc finger protein 282

1

20

High-throughput

0.489

High

1458872

KLDC2
Kelch domain-containing protein 2

1

4

High-throughput

0.489

High

1458873

ARIP4
Helicase ARIP4

1

10

High-throughput

0.489

High

424610

PAI1
Plasminogen activator inhibitor 1

1

3

Small-scale

0.479

High

694047

RL10
Large ribosomal subunit protein uL16

1

5

High-throughput

0.479

High

848305

MAGA3
Melanoma-associated antigen 3

1

3

Small-scale

0.479

High

1294191

CEP57
Centrosomal protein of 57 kDa

1

1

High-throughput

0.479

High

1367950

AP2C
Transcription factor AP-2 gamma

1

8

High-throughput

0.457

High

709311

CCN2
CCN family member 2

1

8

High-throughput

0.445

High

1100491

TIF1B
Transcription intermediary factor 1-beta

1

10

High-throughput

0.445

High

1458871

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.445

High

106790

APRIO
Alternative prion protein

1

2

Small-scale

0.439

High

1257157

PAXI1
PAX-interacting protein 1

1

3

High-throughput

0.439

High

218915

TGON2
Trans-Golgi network integral membrane protein 2

1

16

High-throughput

0.437

High

71021

ZN724
Zinc finger protein 724

1

20

High-throughput

0.407

High

225495

CYH3
Cytohesin-3

1

1

High-throughput

0.407

High

772527

IRS1
Insulin receptor substrate 1

1

4

High-throughput

0.407

High

1346821

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

5

High-throughput

0.407

High

1430158

TKTL2
Transketolase-like protein 2

2

0

High-throughput

0.328

High

319181

ST65G
STAGA complex 65 subunit gamma

1

0

High-throughput

0.279

Low

787809

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

0

High-throughput

0.279

Low

1086518

TROAP
Tastin

1

0

High-throughput

0.279

Low

1205104

FA76B
Protein FAM76B

1

0

High-throughput

0.279

Low

1216589

PR14L
Protein PRR14L

1

0

High-throughput

0.279

Low

1219479

SLX4I
Protein SLX4IP

1

0

High-throughput

0.279

Low

1288022

YRDC
Threonylcarbamoyl-AMP synthase

1

0

High-throughput

0.279

Low

1372169

SBP2L
Selenocysteine insertion sequence-binding protein 2-like

1

0

High-throughput

0.279

Low

1391992

TRM2B
tRNA

1

0

High-throughput

0.279

Low

1429692

IQCN
IQ domain-containing protein N

1

0

High-throughput

0.279

Low

1430616

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.279

Low

1452884

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.279

Low

1453109

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

0

High-throughput

0.279

Low

352580

TOP3B
DNA topoisomerase 3-beta-1

1

0

Small-scale

0.251

Low

350629

TXD12
Thioredoxin domain-containing protein 12

1

0

High-throughput

0.232

Low

1186192

INAVA
Innate immunity activator protein

1

0

High-throughput

0.232

Low

1385000

COA7
Cytochrome c oxidase assembly factor 7

1

0

High-throughput

0.232

Low

1451597

TM160
Transmembrane protein 160

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025