Interactor 1: GRIK2 (Q13002)
Glutamate receptor ionotropic, kainate 2 (GluK2) (Excitatory amino acid receptor 4) (EAA4) (Glutamate receptor 6) (GluR-6) (GluR6)
Gene: GRIK2

Interactor 2: GRIK2 (Q13002)
Glutamate receptor ionotropic, kainate 2 (GluK2) (Excitatory amino acid receptor 4) (EAA4) (Glutamate receptor 6) (GluR-6) (GluR6)
Gene: GRIK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.830

The method score is based on:

Property Details
Experiments 29058671, 21791290, 19465914
Identification Methods pull down, biochemical, x-ray crystallography
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan-Glu_bd~Lig_chan-Glu_bd
Common GO terms GO:0000149 - SNARE binding
GO:0001662 - behavioral fear response
GO:0005234 - extracellularly glutamate-gated ion channel activity
GO:0005886 - plasma membrane
GO:0006874 - intracellular calcium ion homeostasis
and 34 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 908
Hs

1 908
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Last updated: 15 Jul 2024