Interactor 1: TIAM1 (Q13009)
Rho guanine nucleotide exchange factor TIAM1 (T-lymphoma invasion and metastasis-inducing protein 1) (TIAM-1)
Gene: TIAM1

Interactor 2: M3K21 (Q5TCX8)
Mitogen-activated protein kinase kinase kinase 21 (EC 2.7.11.25) (Mitogen-activated protein kinase kinase kinase MLK4) (Mixed lineage kinase 4)
Gene: MAP3K21

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.80 0.553

The method score is based on:

Property Details
Experiments 27173435
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~PK_Tyr_Ser-Thr, PH~SH3_9, RhoGEF~SH3_9
Common GO terms -
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1591
Hs

1 1036
+ Mm
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs

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Last updated: 15 Jul 2024