HitPredict

Interactor 1: CDC16 (Q13042)
Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)
Gene: CDC16

Interactor 2: CDC23 (Q9UJX2)
Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8)
Gene: CDC23

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 26496610, 35271311, 28514442, 27173435, 33961781, 36652389, 20360068
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC3~TPR_11, ANAPC3~TPR_8, ANAPC8~TPR_12, TPR_11~TPR_12, TPR_12~TPR_8
Common GO terms GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007346 - regulation of mitotic cell cycle
GO:0016567 - protein ubiquitination
and 5 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 620
Hs

1 597
+ Xl
+ Sc
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc
+ Sp
+ At
+ Sc
+ Sp
+ Sc
+ Sc
+ At
+ At
+ At
+ Sc

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Last updated: 15 Jul 2024