HitPredict

Interactor 1: FLII (Q13045)
Protein flightless-1 homolog
Gene: FLII

Interactor 2: LRRF2 (Q9Y608)
Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2)
Gene: LRRFIP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.50	0.607

Property	Details
Experiments	33961781, 10366446, 19265123
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1269 Hs			1 721
+	Hs
		1023171 FLII_HUMAN (1-1269): 0: 1206: 100.00		LRRF1_HUMAN (280-458): 7.43e-52: 195: 56.35
+	Hs
		1023209 FLII_HUMAN (1-1269): 0: 1206: 100.00		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		724803 FLII_HUMAN (1-1269): 0: 1206: 100.00		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Hs
		414016 GELS_HUMAN (481-1269): 0: 798: 24.85		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		413844 GELS_HUMAN (481-1269): 0: 798: 24.85		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Dm
		1095695 FLII_DROME (2-305): 2.17e-61: 232: 26.06		Q9VXN3_DROME (355-718): 2.45e-61: 212: 33.97
+	Hs
		313905 SVIL_HUMAN (1056-1267): 1.52e-21: 104: 17.69		MYH2_HUMAN (224-720): 4.9e-17: 88: 10.37
+	Hs
		313766 SVIL_HUMAN (1056-1267): 1.52e-21: 104: 17.69		MYH11_HUMAN (421-721): 1.67e-13: 76.8: 16.56
+	Hs
		313863 SVIL_HUMAN (1056-1267): 1.52e-21: 104: 17.69		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		313906 SVIL_HUMAN (1056-1267): 1.52e-21: 104: 17.69		MYH13_HUMAN (205-636): 4.94e-10: 65.2: 8.28
+	Hs
		313764 SVIL_HUMAN (1056-1267): 1.52e-21: 104: 17.69		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12