HitPredict

Interactor 1: TRI32 (Q13049)
E3 ubiquitin-protein ligase TRIM32 (EC 2.3.2.27) (72 kDa Tat-interacting protein) (RING-type E3 ubiquitin transferase TRIM32) (Tripartite motif-containing protein 32) (Zinc finger protein HT2A)
Gene: TRIM32

Interactor 2: TRIM5 (Q9C035)
Tripartite motif-containing protein 5 (EC 2.3.2.27) (RING finger protein 88) (RING-type E3 ubiquitin transferase TRIM5)
Gene: TRIM5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.53 1.00 0.733

The method score is based on:

Property Details
Experiments 22493164
Identification Methods two hybrid, two hybrid array, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-B_box~zf-RING_UBOX, zf-RING_UBOX~zf-RING_UBOX
Common GO terms GO:0000209 - protein polyubiquitination
GO:0003713 - transcription coactivator activity
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 10 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 653
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Last updated: 15 Jul 2024