HitPredict

Interactor 1: CSN1 (Q13098)
COP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1) (Protein MFH)
Gene: GPS1

Interactor 2: DDB1 (Q16531)
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
Gene: DDB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.717

Property	Details
Experiments	27029275, 33961781, 35271311, 16949367, 22767593
Identification Methods	fluorescent resonance energy transfer, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 491 Hs			1 1140
+	Hs
		897256 CSN2_HUMAN (72-458): 4.14e-76: 247: 14.07		DDB1_HUMAN (1-1140): 0: 1424: 100.00
+	Sp
		143269 CSN1_SCHPO (43-485): 2.4e-84: 268: 25.45		DDB1_SCHPO (5-1140): 0: 835: 24.39
+	Hs
		1014110 CSN1_HUMAN (1-491): 9.03e-163: 471: 100.00		CPSF1_HUMAN (4-527): 4.39e-117: 397: 15.87
+	Hs
		897235 CSN2_HUMAN (72-458): 4.14e-76: 247: 14.07		CPSF1_HUMAN (4-527): 4.39e-117: 397: 15.87