HitPredict

Interactor 1: UBP4 (Q13107)
Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Ubiquitous nuclear protein homolog)
Gene: USP4

Interactor 2: Q4VC15 (Q4VC15)
ubiquitinyl hydrolase 1 (EC 3.4.19.12)
Gene: USP32

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19615732
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UCH~UCH
Common GO terms	GO:0004843 - cysteine-type deubiquitinase activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 963 Hs			1 389
+	Hs
		1024377 UBP4_HUMAN (1-963): 0: 908: 100.00		UBP32_HUMAN (1-389): 1.57e-102: 334: 100.00
+	Hs
		1244193 UBP15_HUMAN (1-924): 0: 749: 58.17		UBP32_HUMAN (1-389): 1.57e-102: 334: 100.00
+	Hs
		1024403 UBP4_HUMAN (1-963): 0: 908: 100.00		UBP28_HUMAN (5-385): 6.68e-45: 167: 18.80
+	Hs
		296297 UBP4_HUMAN (1-963): 0: 908: 100.00		UBP1_HUMAN (4-351): 7.92e-41: 155: 16.35
+	Hs
		1024318 UBP4_HUMAN (1-963): 0: 908: 100.00		UBP4_HUMAN (190-356): 1.12e-22: 102: 20.24
+	Hs
		301380 UBP4_HUMAN (1-963): 0: 908: 100.00		UBP19_HUMAN (182-370): 1.14e-22: 102: 18.09
+	Hs
		850023 UBP4_HUMAN (1-963): 0: 908: 100.00		UBP11_HUMAN (215-361): 1.56e-21: 98.9: 20.95
+	Hs
		1024450 UBP4_HUMAN (1-963): 0: 908: 100.00		UBP15_HUMAN (197-374): 9.32e-20: 93.5: 22.91
+	Hs
		1024442 UBP4_HUMAN (1-963): 0: 908: 100.00		UBP21_HUMAN (281-350): 1.85e-15: 79.8: 32.86
+	Hs
		1301533 UBP15_HUMAN (1-924): 0: 749: 58.17		UBP28_HUMAN (5-385): 6.68e-45: 167: 18.80
+	Hs
		1257047 UBP15_HUMAN (1-924): 0: 749: 58.17		UBP33_HUMAN (253-365): 1.56e-21: 98.9: 20.18
+	Hs
		850247 UBP15_HUMAN (1-924): 0: 749: 58.17		UBP11_HUMAN (215-361): 1.56e-21: 98.9: 20.95
+	Hs
		1174035 UBP15_HUMAN (1-924): 0: 749: 58.17		UBP51_HUMAN (279-355): 1.92e-21: 98.3: 24.68
+	Hs
		1377299 UBP15_HUMAN (1-924): 0: 749: 58.17		UBP20_HUMAN (253-376): 3e-21: 97.7: 21.60
+	Hs
		1377844 UBP15_HUMAN (1-924): 0: 749: 58.17		UBP15_HUMAN (197-374): 9.32e-20: 93.5: 22.91
+	Mm
		1246961 UBP15_MOUSE (1-924): 0: 745: 57.75		UBP15_MOUSE (197-374): 1.5e-19: 92.7: 23.46
+	Hs
		271227 UBP15_HUMAN (1-924): 0: 749: 58.17		UBP2_HUMAN (6-96): 8.38e-18: 87.1: 34.07
+	Hs
		1356322 UBP15_HUMAN (1-924): 0: 749: 58.17		UBP21_HUMAN (281-350): 1.85e-15: 79.8: 32.86
+	Hs
		777091 UBP15_HUMAN (1-924): 0: 749: 58.17		UBP8_HUMAN (215-355): 6.04e-14: 75.7: 21.83