Protein: CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (MELC-CC) (Mouse brain class C) (MBC) (Voltage-gated calcium channel subunit alpha Cav1.2)

Gene: CAC1C, Cacna1c
Organism: Mus musculus
Interactions: 94
UniProt ID: Q01815

Gene Ontology (top 5):
GO:0002095 - caveolar macromolecular signaling complex
GO:0005245 - voltage-gated calcium channel activity
GO:0005516 - calmodulin binding
GO:0005886 - plasma membrane
GO:0005891 - voltage-gated calcium channel complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

97957

RYR2
Ryanodine receptor 2

2

10

Small-scale

0.737

High

905825

CAV3
Caveolin-3

2

2

Small-scale

0.584

High

928753

CACB3
Voltage-dependent L-type calcium channel subunit beta-3

2

20

Small-scale

0.571

High

236440

IL16
Pro-interleukin-16 [Cleaved into: Interleukin-16

1

6

Small-scale

0.568

High

618826

TNNC1
Troponin C, slow skeletal and cardiac muscles

1

4

High-throughput

0.514

High

906628

MLRV
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

1

4

High-throughput

0.514

High

1032726

MLRA
Myosin regulatory light chain 2, atrial isoform

1

4

High-throughput

0.514

High

1032711

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

4

Small-scale

0.479

High

616490

ADRB2
Beta-2 adrenergic receptor

1

0

Small-scale

0.458

High

907954

DYLT1
Dynein light chain Tctex-type 1

1

1

High-throughput

0.457

High

68077

A8DV41
Beta-globin

1

2

High-throughput

0.445

High

237231

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

9

High-throughput

0.445

High

267097

MYPC3
Myosin-binding protein C, cardiac-type

1

9

High-throughput

0.445

High

384341

LAMB1
Laminin subunit beta-1

1

4

High-throughput

0.445

High

518673

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.445

High

569624

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

5

High-throughput

0.445

High

591448

FGFR1
Fibroblast growth factor receptor 1

1

14

High-throughput

0.445

High

890922

CAV1
Caveolin-1

1

2

High-throughput

0.445

High

940815

ATPB
ATP synthase F(1) complex catalytic subunit beta, mitochondrial

1

2

High-throughput

0.445

High

989240

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.445

High

1032692

ODO1
2-oxoglutarate dehydrogenase complex component E1

1

1

High-throughput

0.445

High

1032698

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

7

High-throughput

0.445

High

1032701

Q80TN1
calcium/calmodulin-dependent protein kinase

1

7

High-throughput

0.445

High

1032703

CACB2
Voltage-dependent L-type calcium channel subunit beta-2

1

20

High-throughput

0.445

High

1032705

LRC10
Leucine-rich repeat-containing protein 10

1

1

High-throughput

0.445

High

1032721

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

1

High-throughput

0.445

High

1032724

JPH2
Junctophilin-2

1

5

High-throughput

0.445

High

1032725

JPH1
Junctophilin-1

1

5

High-throughput

0.445

High

1032728

PKP3
Plakophilin-3

1

3

High-throughput

0.445

High

1032730

AT12A
Potassium-transporting ATPase alpha chain 2

1

6

High-throughput

0.445

High

1032695

SQSTM
Sequestosome-1

1

1

Small-scale

0.437

High

1032697

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

1

High-throughput

0.437

High

1032713

TRI13
E3 ubiquitin-protein ligase TRIM13

1

7

Small-scale

0.437

High

555560

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.426

High

571098

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.426

High

956210

PPLA
Phospholamban

1

0

High-throughput

0.426

High

969544

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.426

High

984676

CYC
Cytochrome c, somatic

1

0

High-throughput

0.426

High

1032139

NDKB
Nucleoside diphosphate kinase B

1

0

High-throughput

0.426

High

1032715

CY1
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.426

High

1032719

Q9D881
Cytochrome c oxidase subunit 5B, mitochondrial

1

0

High-throughput

0.426

High

68076

A8DUV1
Alpha-globin

1

2

High-throughput

0.407

High

483498

MYL3
Myosin light chain 3

1

2

High-throughput

0.407

High

542710

FABPH
Fatty acid-binding protein, heart

1

1

High-throughput

0.407

High

570740

RL7
Large ribosomal subunit protein uL30

1

1

High-throughput

0.407

High

575063

LMNB1
Lamin-B1

1

7

High-throughput

0.407

High

619295

RL13A
Large ribosomal subunit protein uL13

1

1

High-throughput

0.407

High

771536

TSP1
Thrombospondin-1

1

9

High-throughput

0.407

High

778145

RL18
Large ribosomal subunit protein eL18

1

1

High-throughput

0.407

High

868409

RL6
Large ribosomal subunit protein eL6

1

1

High-throughput

0.407

High

916484

RL10A
Large ribosomal subunit protein uL1

1

2

High-throughput

0.407

High

920758

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

3

High-throughput

0.407

High

946687

TPM1
Tropomyosin alpha-1 chain

1

2

High-throughput

0.407

High

980644

H4
Histone H4

1

1

High-throughput

0.407

High

984605

RL30
Large ribosomal subunit protein eL30

1

1

High-throughput

0.407

High

1032690

Q3TSA5
PABC domain-containing protein

1

6

High-throughput

0.407

High

1032693

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

1

High-throughput

0.407

High

1032694

SPEG
Striated muscle-specific serine/threonine-protein kinase

1

11

High-throughput

0.407

High

1032696

H2B1H
Histone H2B type 1-H

1

1

High-throughput

0.407

High

1032700

MTCH2
Mitochondrial carrier homolog 2

1

4

High-throughput

0.407

High

1032708

QCR8
Cytochrome b-c1 complex subunit 8

1

1

High-throughput

0.407

High

1032714

RL15
Large ribosomal subunit protein eL15

1

1

High-throughput

0.407

High

1032718

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.407

High

1032720

EF1G
Elongation factor 1-gamma

1

1

High-throughput

0.407

High

1032722

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

2

High-throughput

0.407

High

1032727

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

3

High-throughput

0.407

High

1032729

ECI2
Enoyl-CoA delta isomerase 2

1

2

High-throughput

0.407

High

50303

A1IGX6
Desmoglein4

1

0

High-throughput

0.232

Low

147370

HXK2
Hexokinase-2

1

0

High-throughput

0.232

Low

569697

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.232

Low

627910

TYB4
Thymosin beta-4

1

0

High-throughput

0.232

Low

868954

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.232

Low

894321

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.232

Low

961455

RL27
Large ribosomal subunit protein eL27

1

0

High-throughput

0.232

Low

973664

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.232

Low

977650

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.232

Low

983242

RS26
Small ribosomal subunit protein eS26

1

0

High-throughput

0.232

Low

986303

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.232

Low

1017577

RL10L
Large ribosomal subunit protein uL16-like

1

0

High-throughput

0.232

Low

1021426

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

1

0

High-throughput

0.232

Low

1032688

ATP5I
ATP synthase F(0) complex subunit e, mitochondrial

1

0

High-throughput

0.232

Low

1032689

Q3T9U9
Large ribosomal subunit protein uL3

1

0

High-throughput

0.232

Low

1032691

AFG1L
AFG1-like ATPase

1

0

High-throughput

0.232

Low

1032699

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.232

Low

1032702

SAM50
Sorting and assembly machinery component 50 homolog

1

0

High-throughput

0.232

Low

1032704

ACD10
Acyl-CoA dehydrogenase family member 10

1

0

High-throughput

0.232

Low

1032706

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.232

Low

1032707

DECR
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

1

0

High-throughput

0.232

Low

1032709

NDUA2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

1

0

High-throughput

0.232

Low

1032710

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

0

High-throughput

0.232

Low

1032712

Q9CWK0
Large ribosomal subunit protein eL14

1

0

High-throughput

0.232

Low

1032716

RL34
Large ribosomal subunit protein eL34

1

0

High-throughput

0.232

Low

1032717

MMAB
Corrinoid adenosyltransferase MMAB

1

0

High-throughput

0.232

Low

1032723

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025