HitPredict

Interactor 1: UBP4 (Q13107)
Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.4.19.12) (Deubiquitinating enzyme 4) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Ubiquitous nuclear protein homolog)
Gene: USP4

Interactor 2: SPDLY (Q96EA4)
Protein Spindly (hSpindly) (Arsenite-related gene 1 protein) (Coiled-coil domain-containing protein 99) (Rhabdomyosarcoma antigen MU-RMS-40.4A) (Spindle apparatus coiled-coil domain-containing protein 1)
Gene: SPDL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30258100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 963 Hs			1 605
+	Hs
		1289378 UBP15_HUMAN (1-924): 0: 749: 58.17		SPDLY_HUMAN (1-605): 2.11e-78: 261: 100.00
+	Mm
		1186813 UBP15_MOUSE (1-924): 0: 745: 57.75		MRCKB_MOUSE (5-542): 4.87e-73: 257: 18.02
+	Hs
		850145 UBP11_HUMAN (6-937): 0: 717: 44.60		SPDLY_HUMAN (1-605): 2.11e-78: 261: 100.00
+	Hs
		725273 UBP15_HUMAN (1-924): 0: 749: 58.17		MYH10_HUMAN (4-596): 7.47e-17: 87.1: 11.71
+	Mm
		1246962 UBP15_MOUSE (1-924): 0: 745: 57.75		MYH9_MOUSE (4-596): 2.21e-17: 88.7: 13.91
+	Mm
		1143171 UBP15_MOUSE (1-924): 0: 745: 57.75		MYH10_MOUSE (4-596): 2.89e-16: 85.2: 12.03
+	Mm
		1246991 UBP15_MOUSE (1-924): 0: 745: 57.75		MY18A_MOUSE (36-569): 8.33e-10: 64.4: 13.13
+	Hs
		724724 UBP11_HUMAN (6-937): 0: 717: 44.60		MYH9_HUMAN (4-596): 3.84e-17: 87.9: 13.74
+	Hs
		725119 UBP11_HUMAN (6-937): 0: 717: 44.60		MYH10_HUMAN (4-596): 7.47e-17: 87.1: 11.71
+	Hs
		850129 UBP11_HUMAN (6-937): 0: 717: 44.60		MY18A_HUMAN (36-569): 9.74e-11: 67.1: 14.03
+	Hs
		1174154 UBP45_HUMAN (179-922): 3.26e-95: 321: 17.31		SPDLY_HUMAN (1-605): 2.11e-78: 261: 100.00
+	Hs
		551874 UBP20_HUMAN (203-962): 3.45e-110: 363: 17.72		DESP_HUMAN (15-507): 8.07e-47: 179: 14.37
+	Hs
		725080 UBP20_HUMAN (203-962): 3.45e-110: 363: 17.72		MYH9_HUMAN (4-596): 3.84e-17: 87.9: 13.74
+	Hs
		725271 UBP20_HUMAN (203-962): 3.45e-110: 363: 17.72		MYH10_HUMAN (4-596): 7.47e-17: 87.1: 11.71
+	Hs
		724889 UBP45_HUMAN (179-922): 3.26e-95: 321: 17.31		MYH9_HUMAN (4-596): 3.84e-17: 87.9: 13.74
+	Hs
		725186 UBP45_HUMAN (179-922): 3.26e-95: 321: 17.31		MYH10_HUMAN (4-596): 7.47e-17: 87.1: 11.71
+	Hs
		551869 UBP22_HUMAN (764-928): 2.7e-60: 216: 28.33		DESP_HUMAN (15-507): 8.07e-47: 179: 14.37
+	Hs
		271039 UBP2_HUMAN (604-928): 8.22e-65: 231: 23.55		MYH9_HUMAN (4-596): 3.84e-17: 87.9: 13.74