Protein: MICA3
[F-actin]-monooxygenase MICAL3 (EC 1.14.13.225) (Molecule interacting with CasL protein 3) (MICAL-3)

Gene: MICA3, MICAL3
Organism: Homo sapiens
Interactions: 91
UniProt ID: Q7RTP6

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005819 - spindle
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1273875

NINL
Ninein-like protein

4

14

Small-scale

0.867

High

1273853

RAB8B
Ras-related protein Rab-8B

2

20

High-throughput

0.811

High

955951

RAB8A
Ras-related protein Rab-8A

3

20

Small-scale

0.802

High

375658

RASK
GTPase KRas

2

20

High-throughput

0.754

High

1091420

ANK3
Ankyrin-3

2

18

Small-scale

0.737

High

1035725

KIF23
Kinesin-like protein KIF23

3

16

Small-scale

0.667

High

1193672

CERKL
Ceramide kinase-like protein

3

0

High-throughput

0.634

High

333071

VAPB
Vesicle-associated membrane protein-associated protein B/C

2

4

High-throughput

0.628

High

1273872

VAPA
Vesicle-associated membrane protein-associated protein A

2

4

High-throughput

0.628

High

363487

EGFR
Epidermal growth factor receptor

1

13

High-throughput

0.618

High

463610

LYN
Tyrosine-protein kinase Lyn

1

13

High-throughput

0.618

High

541564

FGFR1
Fibroblast growth factor receptor 1

1

19

High-throughput

0.618

High

601347

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

710333

EPHA2
Ephrin type-A receptor 2

1

13

High-throughput

0.618

High

953526

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

958138

ARP3
Actin-related protein 3

1

20

High-throughput

0.618

High

976366

RB11A
Ras-related protein Rab-11A

1

6

High-throughput

0.618

High

978117

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

988477

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1144980

RAB35
Ras-related protein Rab-35

1

20

High-throughput

0.618

High

1273861

BARD1
BRCA1-associated RING domain protein 1

1

18

High-throughput

0.618

High

1273864

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

1273862

RGAP1
Rac GTPase-activating protein 1

2

12

Small-scale

0.601

High

956742

RAB10
Ras-related protein Rab-10

1

20

Small-scale

0.575

High

996745

TBA1B
Tubulin alpha-1B chain

1

10

Small-scale

0.575

High

1028804

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

17

Small-scale

0.575

High

1117396

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

20

Small-scale

0.575

High

995106

CSK2B
Casein kinase II subunit beta

2

1

Small-scale

0.571

High

1254393

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.553

High

1273843

ANKAR
Ankyrin and armadillo repeat-containing protein

1

15

High-throughput

0.553

High

772875

MYH9
Myosin-9

1

10

High-throughput

0.536

High

866741

CAZA2
F-actin-capping protein subunit alpha-2

1

8

High-throughput

0.536

High

1107562

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

3

High-throughput

0.536

High

1273856

VMP1
Vacuole membrane protein 1

1

1

High-throughput

0.536

High

1273857

MYO19
Unconventional myosin-XIX

1

14

High-throughput

0.536

High

1273869

ANLN
Anillin

1

9

High-throughput

0.536

High

1273874

AKT3
RAC-gamma serine/threonine-protein kinase

1

4

High-throughput

0.536

High

1273876

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

3

High-throughput

0.536

High

1273845

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

706186

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

1273851

MY18A
Unconventional myosin-XVIIIa

1

17

High-throughput

0.489

High

181717

CTDSL
CTD small phosphatase-like protein

1

3

High-throughput

0.479

High

189658

STX7
Syntaxin-7

1

6

High-throughput

0.479

High

242114

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

459649

PROF1
Profilin-1

1

3

High-throughput

0.479

High

574340

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

1

High-throughput

0.479

High

642943

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

6

High-throughput

0.479

High

891219

GSK3A
Glycogen synthase kinase-3 alpha

1

16

High-throughput

0.479

High

891646

GSK3B
Glycogen synthase kinase-3 beta

1

17

High-throughput

0.479

High

920068

PLK1
Serine/threonine-protein kinase PLK1

1

3

High-throughput

0.479

High

951231

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.479

High

1041140

CAV1
Caveolin-1

1

10

High-throughput

0.479

High

1045440

TF65
Transcription factor p65

1

8

High-throughput

0.479

High

1052053

CALD1
Caldesmon

1

20

High-throughput

0.479

High

1087163

STX4
Syntaxin-4

1

6

High-throughput

0.479

High

1129637

MDC1
Mediator of DNA damage checkpoint protein 1

1

19

High-throughput

0.479

High

1140474

KIF14
Kinesin-like protein KIF14

1

13

High-throughput

0.479

High

1141724

EEA1
Early endosome antigen 1

1

20

High-throughput

0.479

High

1156751

E2F4
Transcription factor E2F4

1

1

High-throughput

0.479

High

1159718

OCLN
Occludin

1

3

High-throughput

0.479

High

1273848

FBX22
F-box only protein 22

1

2

High-throughput

0.479

High

1273850

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

6

High-throughput

0.479

High

1273852

ESR2
Estrogen receptor beta

1

16

High-throughput

0.479

High

1273859

SNX27
Sorting nexin-27

1

20

High-throughput

0.479

High

1273865

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1273866

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.479

High

1273867

ECT2
Protein ECT2

1

20

High-throughput

0.479

High

1273873

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

680409

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

892689

DNLI4
DNA ligase 4

1

0

High-throughput

0.458

High

933676

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

High-throughput

0.458

High

1273868

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

1273871

DISC1
Disrupted in schizophrenia 1 protein

1

5

High-throughput

0.457

High

552033

ADT1
ADP/ATP translocase 1

1

1

Small-scale

0.445

High

625463

CSK22
Casein kinase II subunit alpha'

1

5

Small-scale

0.445

High

765655

BMI1
Polycomb complex protein BMI-1

1

15

High-throughput

0.445

High

877157

KC1D
Casein kinase I isoform delta

1

1

High-throughput

0.445

High

1273849

CCHCR
Coiled-coil alpha-helical rod protein 1

1

20

Small-scale

0.445

High

1273854

FBXW7
F-box/WD repeat-containing protein 7

1

3

High-throughput

0.445

High

1273877

CD2AP
CD2-associated protein

1

18

Small-scale

0.445

High

1273855

CK052
Uncharacterized protein C11orf52

1

3

High-throughput

0.437

High

1273860

SEC62
Translocation protein SEC62

1

1

High-throughput

0.437

High

1273870

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.437

High

124388

HAX1
HCLS1-associated protein X-1

1

0

Small-scale

0.426

High

1273847

SHCBP
SHC SH2 domain-binding protein 1

1

0

Small-scale

0.426

High

1273863

APC1
Anaphase-promoting complex subunit 1

1

0

Small-scale

0.426

High

1273878

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

0

Small-scale

0.426

High

1273844

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

20

Small-scale

0.407

High

1273846

MIA40
Mitochondrial intermembrane space import and assembly protein 40

2

0

High-throughput

0.313

High

847576

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.249

Low

1273858

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025