Interactor 1: AAPK1 (Q13131)
5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)
Gene: PRKAA1

Interactor 2: KKCC2 (Q96RR4)
Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)
Gene: CAMKK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31995728
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AdenylateSensor~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006468 - protein phosphorylation
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 559
Hs

1 588
+ Rn
+ Hs
+ Hs
+ At
+ At
+ At
+ At
+ At
+ Zm
+ At
+ Hs
+ Hs
+ At
+ Hs
+ At
+ At
+ At
+ At
+ At

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Last updated: 15 Jul 2024