HitPredict

Interactor 1: LIPA1 (Q13136)
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)
Gene: PPFIA1

Interactor 2: GIT1 (Q9Y2X7)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1)
Gene: GIT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.684

Property	Details
Experiments	17898078, 12629171, 12923177
Identification Methods	affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1202 Hs			1 761
+	Hs
		259656 LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82		GIT1_HUMAN (1-761): 1.3e-176: 527: 100.00
+	Mm
		71323 B2RXW8_MOUSE (1-1202): 4.91e-161: 514: 92.11		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Mm
		82314 B8QI33_MOUSE (1-1202): 1.52e-154: 498: 89.98		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Mm
		1112616 LIPA2_MOUSE (35-1202): 5.01e-134: 442: 62.90		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Hs
		255262 LIPA3_HUMAN (1-265): 3.37e-12: 73.2: 12.45		GIT1_HUMAN (1-761): 1.3e-176: 527: 100.00
+	Hs
		259662 LIPA4_HUMAN (4-235): 6.44e-09: 62.4: 12.34		GIT1_HUMAN (1-761): 1.3e-176: 527: 100.00
+	Hs
		724782 MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37		ANK2_HUMAN (162-494): 7.25e-30: 129: 9.52
+	Hs
		1021425 LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62		ANK3_HUMAN (93-695): 4.85e-40: 162: 12.34
+	Hs
		725139 MYH10_HUMAN (320-813): 7.13e-10: 66: 11.29		ANK2_HUMAN (162-494): 7.25e-30: 129: 9.52