Protein: WDR1
WD repeat-containing protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1)

Gene: WDR1
Organism: Homo sapiens
Interactions: 144
UniProt ID: O75083

Gene Ontology (top 5):
GO:0002102 - podosome
GO:0002446 - neutrophil mediated immunity
GO:0005576 - extracellular region
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

270337

ACTB
Actin, cytoplasmic 1

7

14

High-throughput

0.958

High

270342

ACTG
Actin, cytoplasmic 2

3

14

High-throughput

0.847

High

270404

ANLN
Anillin

3

6

High-throughput

0.847

High

270372

POTEE
POTE ankyrin domain family member E

2

14

High-throughput

0.811

High

270385

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

8

Small-scale

0.789

High

270327

ATRX
Transcriptional regulator ATRX

2

11

High-throughput

0.726

High

270366

DDB1
DNA damage-binding protein 1

1

12

Small-scale

0.724

High

270413

AKT3
RAC-gamma serine/threonine-protein kinase

1

7

High-throughput

0.691

High

270418

SAR1B
Small COPII coat GTPase SAR1B

1

5

High-throughput

0.691

High

270362

SKI2
Superkiller complex protein 2

1

19

High-throughput

0.656

High

156755

CTRO
Citron Rho-interacting kinase

1

10

High-throughput

0.618

High

270288

WDR1
WD repeat-containing protein 1

1

17

High-throughput

0.618

High

270307

VAV
Proto-oncogene vav

1

9

High-throughput

0.618

High

270334

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

8

High-throughput

0.618

High

270340

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

6

High-throughput

0.618

High

270344

ACTC
Actin, alpha cardiac muscle 1

1

12

High-throughput

0.618

High

270377

RHG24
Rho GTPase-activating protein 24

1

5

High-throughput

0.618

High

270386

FBXW7
F-box/WD repeat-containing protein 7

1

15

Small-scale

0.618

High

270400

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

17

Small-scale

0.618

High

270402

PKHA4
Pleckstrin homology domain-containing family A member 4

1

19

High-throughput

0.618

High

270298

P53
Cellular tumor antigen p53

2

7

High-throughput

0.611

High

270303

TAU
Microtubule-associated protein tau

2

14

High-throughput

0.601

High

270341

GRB2
Growth factor receptor-bound protein 2

2

4

High-throughput

0.594

High

270375

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.586

High

270414

PHOCN
MOB-like protein phocein

1

0

High-throughput

0.586

High

240255

PRKN
E3 ubiquitin-protein ligase parkin

2

13

High-throughput

0.584

High

270311

COF1
Cofilin-1

2

7

High-throughput

0.584

High

270352

CUL3
Cullin-3

2

20

Small-scale

0.584

High

270325

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

4

High-throughput

0.575

High

270370

PKHA7
Pleckstrin homology domain-containing family A member 7

1

16

High-throughput

0.575

High

270388

Q96D37
VAV1 protein

1

10

High-throughput

0.575

High

270289

SH3L1
Adapter SH3BGRL

2

1

High-throughput

0.571

High

270317

CALX
Calnexin

2

4

High-throughput

0.571

High

270335

TERA
Transitional endoplasmic reticulum ATPase

2

5

High-throughput

0.571

High

270353

CUL4B
Cullin-4B

1

20

Small-scale

0.561

High

270354

DX39B
Spliceosome RNA helicase DDX39B

1

12

Small-scale

0.553

High

270364

EZH2
Histone-lysine N-methyltransferase EZH2

1

12

High-throughput

0.553

High

270373

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.553

High

123523

MYO1C
Unconventional myosin-Ic

1

10

High-throughput

0.536

High

270306

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

270310

FLNA
Filamin-A

1

10

High-throughput

0.536

High

270322

MYH9
Myosin-9

1

8

High-throughput

0.536

High

270329

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

3

High-throughput

0.536

High

270330

CAZA2
F-actin-capping protein subunit alpha-2

1

1

High-throughput

0.536

High

270331

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.536

High

270333

DAPK1
Death-associated protein kinase 1

1

2

High-throughput

0.536

High

270336

NU107
Nuclear pore complex protein Nup107

1

3

High-throughput

0.536

High

270339

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

5

High-throughput

0.536

High

270350

BIRC3
Baculoviral IAP repeat-containing protein 3

1

7

Small-scale

0.536

High

270351

BIRC2
Baculoviral IAP repeat-containing protein 2

1

9

Small-scale

0.536

High

270357

SRC8
Src substrate cortactin

1

5

High-throughput

0.536

High

270363

MARE1
Microtubule-associated protein RP/EB family member 1

1

4

High-throughput

0.536

High

270367

DREB
Drebrin

1

3

High-throughput

0.536

High

270376

PIM3
Serine/threonine-protein kinase pim-3

1

7

High-throughput

0.536

High

270378

SYNPO
Synaptopodin

1

14

High-throughput

0.536

High

270384

MY18A
Unconventional myosin-XVIIIa

1

12

High-throughput

0.536

High

270390

MYO19
Unconventional myosin-XIX

1

9

High-throughput

0.536

High

270397

TX101
Testis-expressed protein 101

1

1

High-throughput

0.536

High

270411

LIMA1
LIM domain and actin-binding protein 1

1

5

High-throughput

0.536

High

270295

MYC
Myc proto-oncogene protein

2

20

High-throughput

0.533

High

270296

TFR1
Transferrin receptor protein 1

1

1

High-throughput

0.515

High

270300

CATL1
Procathepsin L

1

1

High-throughput

0.515

High

270301

CATB
Cathepsin B

1

3

High-throughput

0.515

High

270305

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.515

High

270313

CATS
Cathepsin S

1

1

High-throughput

0.515

High

270315

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.515

High

270323

BASI
Basigin

1

2

High-throughput

0.515

High

270346

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.515

High

270382

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.515

High

270412

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.515

High

270389

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.513

High

270343

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.508

High

270365

HSPB2
Heat shock protein beta-2

1

3

High-throughput

0.508

High

270379

TBCK
TBC domain-containing protein kinase-like protein

1

8

High-throughput

0.489

High

126396

RHOD
Rho-related GTP-binding protein RhoD

1

6

High-throughput

0.479

High

136031

PLK4
Serine/threonine-protein kinase PLK4

1

10

Small-scale

0.479

High

213733

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

1

Small-scale

0.479

High

222571

PRC1
Protein regulator of cytokinesis 1

1

11

High-throughput

0.479

High

270291

BAG3
BAG family molecular chaperone regulator 3

1

2

High-throughput

0.479

High

270293

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.479

High

270294

FOS
Protein c-Fos

1

7

High-throughput

0.479

High

270297

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.479

High

270299

ISG15
Ubiquitin-like protein ISG15

1

10

High-throughput

0.479

High

270302

CFAH
Complement factor H

1

1

Small-scale

0.479

High

270304

HSP7C
Heat shock cognate 71 kDa protein

1

8

High-throughput

0.479

High

270312

CDK2
Cyclin-dependent kinase 2

1

6

High-throughput

0.479

High

270319

CTNB1
Catenin beta-1

1

7

Small-scale

0.479

High

270324

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

4

High-throughput

0.479

High

270328

YAP1
Transcriptional coactivator YAP1

1

10

High-throughput

0.479

High

270332

SOX2
Transcription factor SOX-2

1

17

High-throughput

0.479

High

270338

ABCE1
ATP-binding cassette sub-family E member 1

1

2

High-throughput

0.479

High

270347

DYST
Dystonin

1

15

High-throughput

0.479

High

270348

FOXC1
Forkhead box protein C1

1

6

High-throughput

0.479

High

270355

KEAP1
Kelch-like ECH-associated protein 1

1

3

Small-scale

0.479

High

270356

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

18

High-throughput

0.479

High

270359

CUL7
Cullin-7

1

5

High-throughput

0.479

High

270360

TNIP1
TNFAIP3-interacting protein 1

1

16

High-throughput

0.479

High

270361

KIF14
Kinesin-like protein KIF14

1

8

High-throughput

0.479

High

270371

RICTR
Rapamycin-insensitive companion of mTOR

1

4

High-throughput

0.479

High

270381

ASB11
Ankyrin repeat and SOCS box protein 11

1

7

High-throughput

0.479

High

270383

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

270387

CHM4C
Charged multivesicular body protein 4c

1

6

High-throughput

0.479

High

270391

RHOV
Rho-related GTP-binding protein RhoV

1

7

High-throughput

0.479

High

270395

NECD
Necdin

1

8

High-throughput

0.479

High

270396

ANM1
Protein arginine N-methyltransferase 1

1

6

High-throughput

0.479

High

270398

ACE2
Angiotensin-converting enzyme 2

1

3

High-throughput

0.479

High

270399

RHBT2
Rho-related BTB domain-containing protein 2

1

16

High-throughput

0.479

High

270401

CHM4B
Charged multivesicular body protein 4b

1

6

High-throughput

0.479

High

270403

ECT2
Protein ECT2

1

13

High-throughput

0.479

High

270407

TLS1
Splicing factor C9orf78

1

3

High-throughput

0.479

High

270409

HDAC6
Protein deacetylase HDAC6

1

6

High-throughput

0.479

High

270410

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

270292

TOP3B
DNA topoisomerase 3-beta-1

1

1

High-throughput

0.470

High

270374

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

4

Small-scale

0.470

High

270318

PURA2
Adenylosuccinate synthetase isozyme 2

1

0

High-throughput

0.458

High

270405

TMPS4
Transmembrane protease serine 4

1

0

High-throughput

0.458

High

270408

TR10D
Tumor necrosis factor receptor superfamily member 10D

1

0

High-throughput

0.458

High

254672

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.445

High

270320

BMI1
Polycomb complex protein BMI-1

1

11

High-throughput

0.445

High

270369

KLH22
Kelch-like protein 22

1

4

High-throughput

0.445

High

270392

CEP63
Centrosomal protein of 63 kDa

1

18

High-throughput

0.445

High

270393

SRPK1
SRSF protein kinase 1

1

15

High-throughput

0.445

High

104933

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

227272

SPOP
Speckle-type POZ protein

1

7

High-throughput

0.437

High

247557

NUPR1
Nuclear protein 1

1

4

High-throughput

0.437

High

259200

BRD4
Bromodomain-containing protein 4

1

17

High-throughput

0.437

High

270290

KI20A
Kinesin-like protein KIF20A

1

16

High-throughput

0.437

High

270308

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.437

High

270309

CEBPB
CCAAT/enhancer-binding protein beta

1

4

High-throughput

0.437

High

270314

U2AF2
Splicing factor U2AF 65 kDa subunit

1

13

High-throughput

0.437

High

270316

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

270321

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

270326

MAGA3
Melanoma-associated antigen 3

1

8

Small-scale

0.437

High

270345

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.437

High

270349

TIF1B
Transcription intermediary factor 1-beta

1

9

High-throughput

0.437

High

270358

RBM39
RNA-binding protein 39

1

10

High-throughput

0.437

High

270368

DUS28
Dual specificity phosphatase 28

1

2

High-throughput

0.437

High

270406

BCLF1
Bcl-2-associated transcription factor 1

1

5

High-throughput

0.437

High

270394

ZBT18
Zinc finger and BTB domain-containing protein 18

1

4

High-throughput

0.407

High

270380

HASP
Serine/threonine-protein kinase haspin

1

0

High-throughput

0.279

Low

270417

MB212
Protein mab-21-like 2

1

0

High-throughput

0.279

Low

270415

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.249

Low

270416

PPME1
Protein phosphatase methylesterase 1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025