HitPredict

Interactor 1: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Interactor 2: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.50	0.619

Property	Details
Experiments	31304625, 33577621, 21903422
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 446 Hs			1 540
+	Hs
		1190020 TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87		MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00
+	Mm
		1112817 TAXB1_MOUSE (13-439): 3.84e-36: 143: 21.23		MAVS_MOUSE (1-538): 5.1e-46: 170: 47.68
+	Hs
		1056882 TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87		MDC1_HUMAN (105-516): 3.47e-10: 65.2: 10.48
+	Hs
		256716 RFIP3_HUMAN (188-428): 5.44e-12: 69.8: 11.62		ASAP1_HUMAN (95-423): 4.61e-23: 105: 13.43
+	Hs
		724896 MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05		HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36
+	Hs
		1186077 MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81		MICA3_HUMAN (68-506): 7.25e-20: 96: 12.82
+	Hs
		724893 MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05		MICA3_HUMAN (68-506): 7.25e-20: 96: 12.82
+	Hs
		1300969 DAPLE_HUMAN (154-345): 5.26e-09: 61: 20.71		CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58
+	Rn
		1126747 Q5JC29_RAT (77-225): 3.69e-09: 60.9: 9.93		SYNJ1_RAT (195-540): 4.5e-09: 61.4: 11.02