Protein: SYNPO
Synaptopodin

Gene: SYNPO
Organism: Homo sapiens
Interactions: 201
UniProt ID: Q8N3V7

Gene Ontology (top 5):
GO:0001725 - stress fiber
GO:0003779 - actin binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1325452

ANLN
Anillin

3

6

High-throughput

0.656

High

555718

ACTN1
Alpha-actinin-1

2

11

High-throughput

0.621

High

222142

NCK2
Cytoplasmic protein NCK2

2

19

Small-scale

0.619

High

347808

BAG3
BAG family molecular chaperone regulator 3

2

2

Small-scale

0.611

High

786722

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

2

10

High-throughput

0.611

High

1325439

CDC5L
Cell division cycle 5-like protein

2

5

High-throughput

0.606

High

106261

APRIO
Alternative prion protein

3

6

High-throughput

0.585

High

1325437

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

10

Small-scale

0.578

High

594047

NCK1
SH2/SH3 adapter protein NCK1

1

20

Small-scale

0.561

High

404838

PRIO
Major prion protein

2

1

Small-scale

0.552

High

987770

GRB2
Growth factor receptor-bound protein 2

2

20

High-throughput

0.552

High

966606

1433G
14-3-3 protein gamma

1

20

High-throughput

0.541

High

123768

MYO1C
Unconventional myosin-Ic

1

11

High-throughput

0.536

High

159238

ABLM1
Actin-binding LIM protein 1

1

5

High-throughput

0.536

High

171275

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

10

High-throughput

0.536

High

171734

GAK
Cyclin-G-associated kinase

1

2

High-throughput

0.536

High

174779

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

17

High-throughput

0.536

High

179227

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

12

High-throughput

0.536

High

192731

ARPC5
Actin-related protein 2/3 complex subunit 5

1

1

High-throughput

0.536

High

208702

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

5

High-throughput

0.536

High

212673

DAPK3
Death-associated protein kinase 3

1

4

High-throughput

0.536

High

224746

ACTN4
Alpha-actinin-4

1

11

High-throughput

0.536

High

227921

MYO1B
Unconventional myosin-Ib

1

11

High-throughput

0.536

High

239323

MYPT2
Protein phosphatase 1 regulatory subunit 12B

1

10

High-throughput

0.536

High

244590

SI1L3
Signal-induced proliferation-associated 1-like protein 3

1

5

High-throughput

0.536

High

270378

WDR1
WD repeat-containing protein 1

1

14

High-throughput

0.536

High

292461

PALM
Paralemmin-1

1

1

High-throughput

0.536

High

299284

FLOT1
Flotillin-1

1

3

High-throughput

0.536

High

320251

SRBS2
Sorbin and SH3 domain-containing protein 2

1

20

High-throughput

0.536

High

328697

VAMP5
Vesicle-associated membrane protein 5

1

3

High-throughput

0.536

High

344742

AP2A1
AP-2 complex subunit alpha-1

1

7

High-throughput

0.536

High

401135

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

10

High-throughput

0.536

High

418702

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

2

High-throughput

0.536

High

442399

GELS
Gelsolin

1

3

High-throughput

0.536

High

456791

ANXA2
Annexin A2

1

2

High-throughput

0.536

High

464184

TPM2
Tropomyosin beta chain

1

4

High-throughput

0.536

High

475996

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

2

High-throughput

0.536

High

483150

CLCA
Clathrin light chain A

1

3

High-throughput

0.536

High

483367

CLCB
Clathrin light chain B

1

3

High-throughput

0.536

High

572324

CBPM
Carboxypeptidase M

1

1

High-throughput

0.536

High

577823

PLAK
Junction plakoglobin

1

11

High-throughput

0.536

High

591328

CD44
CD44 antigen

1

2

High-throughput

0.536

High

637627

FLNA
Filamin-A

1

17

High-throughput

0.536

High

660115

COF1
Cofilin-1

1

4

High-throughput

0.536

High

667932

CDK2
Cyclin-dependent kinase 2

1

4

High-throughput

0.536

High

668659

APC
Adenomatous polyposis coli protein

1

12

High-throughput

0.536

High

687265

HMGB2
High mobility group protein B2

1

20

High-throughput

0.536

High

702013

TMOD1
Tropomodulin-1

1

2

High-throughput

0.536

High

714914

EF1D
Elongation factor 1-delta

1

1

High-throughput

0.536

High

772902

MYH9
Myosin-9

1

2

High-throughput

0.536

High

839795

EPS15
Epidermal growth factor receptor substrate 15

1

3

High-throughput

0.536

High

862901

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

4

High-throughput

0.536

High

866757

CAZA2
F-actin-capping protein subunit alpha-2

1

3

High-throughput

0.536

High

867270

CAPZB
F-actin-capping protein subunit beta

1

5

High-throughput

0.536

High

909094

NEK4
Serine/threonine-protein kinase Nek4

1

4

High-throughput

0.536

High

952957

ACTB
Actin, cytoplasmic 1

1

10

High-throughput

0.536

High

958149

ARP3
Actin-related protein 3

1

10

High-throughput

0.536

High

958308

ARP2
Actin-related protein 2

1

9

High-throughput

0.536

High

967218

RRAS2
Ras-related protein R-Ras2

1

7

High-throughput

0.536

High

967851

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

10

High-throughput

0.536

High

968376

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

10

High-throughput

0.536

High

983529

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

11

High-throughput

0.536

High

984194

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

11

High-throughput

0.536

High

989757

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

2

High-throughput

0.536

High

1010325

BASP1
Brain acid soluble protein 1

1

5

High-throughput

0.536

High

1022179

DAB2
Disabled homolog 2

1

5

High-throughput

0.536

High

1026128

CLH1
Clathrin heavy chain 1

1

3

High-throughput

0.536

High

1082553

NEXN
Nexilin

1

5

High-throughput

0.536

High

1085898

TWF1
Twinfilin-1

1

4

High-throughput

0.536

High

1091689

MYO1E
Unconventional myosin-Ie

1

10

High-throughput

0.536

High

1110378

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

2

High-throughput

0.536

High

1117907

BACD2
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

1

10

High-throughput

0.536

High

1120760

DSG2
Desmoglein-2

1

3

High-throughput

0.536

High

1124648

SRC8
Src substrate cortactin

1

20

High-throughput

0.536

High

1124855

FLOT2
Flotillin-2

1

3

High-throughput

0.536

High

1127733

HLTF
Helicase-like transcription factor

1

9

High-throughput

0.536

High

1128430

ITPR3
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3

1

3

High-throughput

0.536

High

1129010

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

1

3

High-throughput

0.536

High

1129837

EPN4
Clathrin interactor 1

1

5

High-throughput

0.536

High

1152151

MARE1
Microtubule-associated protein RP/EB family member 1

1

3

High-throughput

0.536

High

1160686

DREB
Drebrin

1

5

High-throughput

0.536

High

1177026

INF2
Inverted formin-2

1

1

High-throughput

0.536

High

1195323

TPRN
Taperin

1

1

High-throughput

0.536

High

1208046

CYTSB
Cytospin-B

1

17

High-throughput

0.536

High

1213067

RHG21
Rho GTPase-activating protein 21

1

4

High-throughput

0.536

High

1215475

CE162
Centrosomal protein of 162 kDa

1

15

High-throughput

0.536

High

1229825

CYTSA
Cytospin-A

1

11

High-throughput

0.536

High

1239713

PPR18
Phostensin

1

9

High-throughput

0.536

High

1242417

RHGBA
Rho GTPase-activating protein 11A

1

4

High-throughput

0.536

High

1250734

MPRIP
Myosin phosphatase Rho-interacting protein

1

9

High-throughput

0.536

High

1260567

SSH2
Protein phosphatase Slingshot homolog 2

1

2

High-throughput

0.536

High

1286517

PHLB2
Pleckstrin homology-like domain family B member 2

1

16

High-throughput

0.536

High

1289944

LUZP1
Leucine zipper protein 1

1

17

High-throughput

0.536

High

1325053

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

1

High-throughput

0.536

High

1325425

RAI3
Retinoic acid-induced protein 3

1

2

High-throughput

0.536

High

1325426

LMO7
LIM domain only protein 7

1

5

High-throughput

0.536

High

1325427

STON2
Stonin-2

1

3

High-throughput

0.536

High

1325432

AP2M1
AP-2 complex subunit mu

1

3

High-throughput

0.536

High

1325434

MYO19
Unconventional myosin-XIX

1

10

High-throughput

0.536

High

1325436

ARHGH
Rho guanine nucleotide exchange factor 17

1

10

High-throughput

0.536

High

1325438

NEB2
Neurabin-2

1

17

High-throughput

0.536

High

1325441

DNJC7
DnaJ homolog subfamily C member 7

1

8

High-throughput

0.536

High

1325444

ARP5L
Actin-related protein 2/3 complex subunit 5-like protein

1

1

High-throughput

0.536

High

1325445

COR1B
Coronin-1B

1

18

High-throughput

0.536

High

1325446

LZTS2
Leucine zipper putative tumor suppressor 2

1

15

High-throughput

0.536

High

1325447

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.536

High

1325450

ZBT20
Zinc finger and BTB domain-containing protein 20

1

5

High-throughput

0.536

High

1325453

MYO5C
Unconventional myosin-Vc

1

5

High-throughput

0.536

High

1325454

PDLI7
PDZ and LIM domain protein 7

1

4

High-throughput

0.536

High

1325455

BMP2K
BMP-2-inducible protein kinase

1

2

High-throughput

0.536

High

1325458

TMOD3
Tropomodulin-3

1

1

High-throughput

0.536

High

1325459

RAI14
Ankycorbin

1

10

High-throughput

0.536

High

1325460

CING
Cingulin

1

3

High-throughput

0.536

High

1325461

ADDG
Gamma-adducin

1

2

High-throughput

0.536

High

1325462

LIMA1
LIM domain and actin-binding protein 1

1

8

High-throughput

0.536

High

1325463

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

7

High-throughput

0.536

High

1325464

NEB1
Neurabin-1

1

14

High-throughput

0.536

High

1325465

MYO5B
Unconventional myosin-Vb

1

5

High-throughput

0.536

High

1325466

COR1C
Coronin-1C

1

18

High-throughput

0.536

High

1325467

MYO6
Unconventional myosin-VI

1

8

High-throughput

0.536

High

1325469

COF2
Cofilin-2

1

4

High-throughput

0.536

High

1325472

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

14

High-throughput

0.536

High

1325473

MYO5A
Unconventional myosin-Va

1

6

High-throughput

0.536

High

1325475

KC1G3
Casein kinase I isoform gamma-3

1

4

High-throughput

0.536

High

1277854

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.518

High

131184

CLIC1
Chloride intracellular channel protein 1

1

0

High-throughput

0.513

High

135964

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

0

High-throughput

0.513

High

179372

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

High-throughput

0.513

High

179535

ARPC3
Actin-related protein 2/3 complex subunit 3

1

0

High-throughput

0.513

High

271166

COBL
Protein cordon-bleu

1

0

High-throughput

0.513

High

569201

CD59
CD59 glycoprotein

1

0

High-throughput

0.513

High

948447

ARPC4
Actin-related protein 2/3 complex subunit 4

1

0

High-throughput

0.513

High

1035523

CENPE
Centromere-associated protein E

1

0

High-throughput

0.513

High

1120470

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

1200535

CYBR1
Plasma membrane ascorbate-dependent reductase CYBRD1

1

0

High-throughput

0.513

High

1251495

CD109
CD109 antigen

1

0

High-throughput

0.513

High

1309127

MISP
Mitotic interactor and substrate of PLK1

1

0

High-throughput

0.513

High

1325422

AFAP1
Actin filament-associated protein 1

1

0

High-throughput

0.513

High

1325442

NP1L4
Nucleosome assembly protein 1-like 4

1

0

High-throughput

0.513

High

1325468

ABCG2
Broad substrate specificity ATP-binding cassette transporter ABCG2

1

0

High-throughput

0.513

High

1209968

TM201
Transmembrane protein 201

1

1

High-throughput

0.489

High

1233707

TWF2
Twinfilin-2

1

4

High-throughput

0.489

High

1325424

POC1A
POC1 centriolar protein homolog A

1

15

High-throughput

0.489

High

1325428

MY18A
Unconventional myosin-XVIIIa

1

7

High-throughput

0.489

High

1325429

COR2A
Coronin-2A

1

18

High-throughput

0.489

High

1325470

PLAK2
PALM2-AKAP2 fusion protein

1

1

High-throughput

0.489

High

1325474

LRRF2
Leucine-rich repeat flightless-interacting protein 2

1

6

High-throughput

0.489

High

990491

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.481

High

1144415

NONO
Non-POU domain-containing octamer-binding protein

1

11

High-throughput

0.481

High

157608

CTRO
Citron Rho-interacting kinase

1

10

High-throughput

0.479

High

175119

SC16A
Protein transport protein Sec16A

1

9

High-throughput

0.479

High

248735

PEPL
Periplakin

1

18

High-throughput

0.479

High

278122

FLNB
Filamin-B

1

17

High-throughput

0.479

High

331139

KI20A
Kinesin-like protein KIF20A

1

13

High-throughput

0.479

High

336453

SVIL
Supervillin

1

3

High-throughput

0.479

High

372564

MYC
Myc proto-oncogene protein

1

16

High-throughput

0.479

High

482928

TPM1
Tropomyosin alpha-1 chain

1

4

High-throughput

0.479

High

537510

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

551154

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.479

High

659917

H2B1O
Histone H2B type 1-O

1

20

High-throughput

0.479

High

714267

PML
Protein PML

1

15

High-throughput

0.479

High

943393

H2BFS
Histone H2B type F-S

1

20

High-throughput

0.479

High

1017020

H33
Histone H3.3

1

18

High-throughput

0.479

High

1028817

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

15

High-throughput

0.479

High

1045513

TF65
Transcription factor p65

1

11

High-throughput

0.479

High

1093270

FLII
Protein flightless-1 homolog

1

3

High-throughput

0.479

High

1117410

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

14

High-throughput

0.479

High

1140553

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.479

High

1143190

PLEC
Plectin

1

13

High-throughput

0.479

High

1325430

SH3K1
SH3 domain-containing kinase-binding protein 1

1

20

High-throughput

0.479

High

1325431

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

1325443

H2B1N
Histone H2B type 1-N

1

20

High-throughput

0.479

High

1325449

ECT2
Protein ECT2

1

11

High-throughput

0.479

High

1325451

SCUB2
Signal peptide, CUB and EGF-like domain-containing protein 2

1

4

High-throughput

0.470

High

178328

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

1325448

WNK1
Serine/threonine-protein kinase WNK1

1

11

High-throughput

0.457

High

116467

H7BYY1
Tropomyosin 1

1

4

High-throughput

0.445

High

639147

SYT1
Synaptotagmin-1

1

1

High-throughput

0.445

High

708856

PTN4
Tyrosine-protein phosphatase non-receptor type 4

1

14

High-throughput

0.445

High

717899

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

4

High-throughput

0.445

High

765703

BMI1
Polycomb complex protein BMI-1

1

13

High-throughput

0.445

High

1023832

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

3

High-throughput

0.445

High

1034024

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

2

High-throughput

0.445

High

1103269

CTBP1
C-terminal-binding protein 1

1

6

High-throughput

0.445

High

1234862

PKHA7
Pleckstrin homology domain-containing family A member 7

1

12

High-throughput

0.445

High

1325421

FXL16
F-box/LRR-repeat protein 16

1

1

High-throughput

0.445

High

1325423

CCD89
Coiled-coil domain-containing protein 89

1

2

High-throughput

0.445

High

1325440

ZBT18
Zinc finger and BTB domain-containing protein 18

1

13

High-throughput

0.445

High

1325471

2ABG
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform

1

3

High-throughput

0.445

High

1325457

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

2

High-throughput

0.437

High

340649

STABP
STAM-binding protein

1

0

High-throughput

0.426

High

1293783

FBX11
F-box only protein 11

1

0

High-throughput

0.426

High

1325456

TEX10
Testis-expressed protein 10

1

0

High-throughput

0.426

High

97097

E9PMS6
LIM domain 7

1

6

High-throughput

0.407

High

117251

K7EKI8
Periplakin

1

20

High-throughput

0.407

High

1231124

SCAR3
Scavenger receptor class A member 3

1

2

High-throughput

0.407

High

1278538

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

1

2

High-throughput

0.407

High

1325435

SPF45
Splicing factor 45

1

9

High-throughput

0.407

High

1325433

SGF29
SAGA-associated factor 29

2

0

High-throughput

0.316

High

270026

XYLK
Glycosaminoglycan xylosylkinase

1

0

High-throughput

0.232

Low

653433

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025