HitPredict

Interactor 1: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Interactor 2: CEP89 (Q96ST8)
Centrosomal protein of 89 kDa (Cep89) (Centrosomal protein 123) (Cep123) (Coiled-coil domain-containing protein 123)
Gene: CEP89

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 446 Hs			1 783
+	Hs
		724805 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		MYH9_HUMAN (268-774): 1.96e-23: 109: 12.33
+	Hs
		528370 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		MYH6_HUMAN (321-774): 1.81e-18: 92.9: 11.65
+	Hs
		1025488 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		MY18A_HUMAN (39-550): 9.2e-17: 87.5: 10.73
+	Hs
		1255126 DLG5_HUMAN (77-439): 7.24e-18: 88.6: 10.03		CEP89_HUMAN (1-783): 8.03e-53: 198: 100.00
+	Hs
		1025566 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		MYO5C_HUMAN (258-750): 2.4e-11: 69.7: 13.37
+	Hs
		725151 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		MYH10_HUMAN (451-777): 3.75e-11: 69.4: 10.61
+	Hs
		551687 CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00		DESP_HUMAN (240-774): 6.79e-11: 68.5: 14.29
+	Rn
		222472 MRCKA_RAT (81-439): 8.89e-16: 82.1: 10.80		MRCKA_RAT (197-717): 1.26e-50: 194: 17.73
+	Hs
		1137871 MRCKA_HUMAN (213-416): 6.71e-11: 66.7: 10.28		MRCKA_HUMAN (197-717): 8.92e-48: 186: 17.03
+	Hs
		1201957 TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87		MRCKB_HUMAN (408-744): 1.12e-17: 90.5: 15.30
+	Hs
		724943 MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81		MYH9_HUMAN (268-774): 1.96e-23: 109: 12.33
+	Rn
		222476 MRCKA_RAT (81-439): 8.89e-16: 82.1: 10.80		MRCKB_RAT (375-755): 6.26e-18: 91.2: 14.43
+	Hs
		724698 EPS15_HUMAN (77-234): 4.48e-10: 64: 11.88		MYH9_HUMAN (268-774): 1.96e-23: 109: 12.33
+	Rn
		1186812 MRCKB_RAT (123-433): 1.73e-11: 68.6: 14.62		MRCKB_RAT (375-755): 6.26e-18: 91.2: 14.43
+	Hs
		1137917 MRCKA_HUMAN (213-416): 6.71e-11: 66.7: 10.28		MRCKB_HUMAN (408-744): 1.12e-17: 90.5: 15.30
+	Hs
		1268126 MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81		MRCKB_HUMAN (408-744): 1.12e-17: 90.5: 15.30
+	Hs
		1268060 MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81		MY18A_HUMAN (39-550): 9.2e-17: 87.5: 10.73
+	Hs
		149126 MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81		CTRO_HUMAN (73-685): 3.76e-13: 75.8: 12.74
+	Hs
		1268099 MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81		MYO5C_HUMAN (258-750): 2.4e-11: 69.7: 13.37