HitPredict

Interactor 1: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Interactor 2: ELAV1 (Q15717)
ELAV-like protein 1 (Hu-antigen R) (HuR)
Gene: ELAVL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 20020773, 32814053
Identification Methods affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid, luminescence based mammalian interactome mapping
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~RRM_1
Common GO terms GO:0003723 - RNA binding
GO:0003730 - mRNA 3'-UTR binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0010494 - cytoplasmic stress granule
and 1 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 414
Hs

1 326
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Last updated: 15 Jul 2024