HitPredict

Interactor 1: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Interactor 2: HDAC6 (Q9UBN7)
Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Protein deacetylase HDAC6) (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.601

The method score is based on:

Property Details
Experiments 23703321, 32814053
Identification Methods affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0031647 - regulation of protein stability
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 414
Hs

1 1215
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024