HitPredict - High confidence protein-protein interactions

Method score	Annotation score	Interaction score
0.96	1.00	0.980

Method score

Annotation score

Interaction score

0.96

1.00

0.980

Property	Details
Experiments	18586681, 31980649, 11804587, 10975528, 16278681, 10995762, 10980699, 7618083, 17389360, 22153498, 20936779, 10559936
Identification Methods	enzymatic study, affinity chromatography technology, x-ray crystallography, protein kinase assay, two hybrid pooling approach
Interaction Type	direct interaction, physical association, association, phosphorylation reaction

Property

Details

Experiments

18586681, 31980649, 11804587, 10975528, 16278681, 10995762, 10980699, 7618083, 17389360, 22153498, 20936779, 10559936

Identification Methods

enzymatic study, affinity chromatography technology, x-ray crystallography, protein kinase assay, two hybrid pooling approach

Interaction Type

direct interaction, physical association, association, phosphorylation reaction

Property	Details
Interacting Pfam domains	PBD~PBD, PBD~Pkinase, Pkinase~Pkinase
Common GO terms	GO:0001726 - ruffle GO:0001934 - positive regulation of protein phosphorylation GO:0002223 - stimulatory C-type lectin receptor signaling pathway GO:0004672 - protein kinase activity GO:0004674 - protein serine/threonine kinase activity and 51 others more... GO:0005518 - collagen binding GO:0005524 - ATP binding GO:0005654 - nucleoplasm GO:0005694 - chromosome GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0005884 - actin filament GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0005925 - focal adhesion GO:0006338 - chromatin remodeling GO:0006468 - protein phosphorylation GO:0006887 - exocytosis GO:0006915 - apoptotic process GO:0006974 - DNA damage response GO:0008284 - positive regulation of cell population proliferation GO:0014704 - intercalated disc GO:0016310 - phosphorylation GO:0016477 - cell migration GO:0030018 - Z disc GO:0030027 - lamellipodium GO:0030036 - actin cytoskeleton organization GO:0030335 - positive regulation of cell migration GO:0030424 - axon GO:0030425 - dendrite GO:0031116 - positive regulation of microtubule polymerization GO:0031965 - nuclear membrane GO:0032587 - ruffle membrane GO:0032956 - regulation of actin cytoskeleton organization GO:0032991 - protein-containing complex GO:0033138 - positive regulation of peptidyl-serine phosphorylation GO:0033148 - positive regulation of intracellular estrogen receptor signaling pathway GO:0035556 - intracellular signal transduction GO:0038096 - Fc-gamma receptor signaling pathway involved in phagocytosis GO:0042060 - wound healing GO:0043015 - gamma-tubulin binding GO:0043408 - regulation of MAPK cascade GO:0043507 - positive regulation of JUN kinase activity GO:0046777 - protein autophosphorylation GO:0048012 - hepatocyte growth factor receptor signaling pathway GO:0048013 - ephrin receptor signaling pathway GO:0048754 - branching morphogenesis of an epithelial tube GO:0048812 - neuron projection morphogenesis GO:0050770 - regulation of axonogenesis GO:0051179 - localization GO:0051496 - positive regulation of stress fiber assembly GO:0060244 - negative regulation of cell proliferation involved in contact inhibition GO:0090063 - positive regulation of microtubule nucleation GO:0106310 - protein serine kinase activity GO:1903608 - protein localization to cytoplasmic stress granule
Homologous interactions	18