HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: CHD9 (Q3L8U1)
Chromodomain-helicase-DNA-binding protein 9 (CHD-9) (EC 3.6.4.12) (ATP-dependent helicase CHD9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin-remodeling factor CHROM1) (Kismet homolog 2) (PPAR-alpha-interacting complex protein 320 kDa) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein)
Gene: CHD9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36129980
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Chromo~Chromo, Chromo~SNF2-rel_dom
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 2897
+	Hs
		1027300 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD7_HUMAN (1-2890): 0: 2275: 47.36
+	Hs
		1027277 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD8_HUMAN (1-2696): 0: 1790: 46.84
+	Hs
		229384 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		SMCA5_HUMAN (708-1762): 0: 866: 25.19
+	Hs
		658667 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		SMCA1_HUMAN (751-1756): 0: 860: 26.03
+	Hs
		1027145 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD5_HUMAN (526-1753): 0: 839: 25.52
+	Hs
		1027001 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD4_HUMAN (515-1605): 0: 820: 27.71
+	Hs
		1018451 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD3_HUMAN (440-1914): 0: 818: 23.97
+	Hs
		151406 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD1_HUMAN (482-1832): 0: 818: 23.99
+	Mm
		1161080 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		CHD4_MOUSE (515-1605): 0: 816: 27.71
+	Hs
		658650 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		SMCA1_HUMAN (751-1756): 0: 860: 26.03
+	Hs
		800380 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		CHD4_HUMAN (515-1605): 0: 820: 27.71
+	Hs
		800360 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		CHD3_HUMAN (440-1914): 0: 818: 23.97
+	Hs
		949784 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		CHD4_HUMAN (515-1605): 0: 820: 27.71
+	Hs
		949764 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		CHD3_HUMAN (440-1914): 0: 818: 23.97
+	Mm
		949943 CBX1_MOUSE (36-180): 1.02e-53: 170: 71.33		CHD4_MOUSE (515-1605): 0: 816: 27.71
+	Hs
		203687 SUV91_HUMAN (3-179): 4.73e-40: 141: 16.20		CHD4_HUMAN (515-1605): 0: 820: 27.71
+	Hs
		846954 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		SMCA4_HUMAN (240-795): 9.37e-11: 70.1: 8.98
+	Hs
		800320 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		SMCA4_HUMAN (240-795): 9.37e-11: 70.1: 8.98
+	Hs
		846923 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		SMCA4_HUMAN (240-795): 9.37e-11: 70.1: 8.98
+	Hs
		847118 CDYL_HUMAN (16-165): 6.53e-34: 127: 25.16		SMCA4_HUMAN (240-795): 9.37e-11: 70.1: 8.98