Protein: REEP6
Receptor expression-enhancing protein 6 (Polyposis locus protein 1-like 1)

Gene: REEP6
Organism: Homo sapiens
Interactions: 123
UniProt ID: Q96HR9

Gene Ontology (top 5):
GO:0001917 - photoreceptor inner segment
GO:0005634 - nucleus
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0007029 - endoplasmic reticulum organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1393435

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

5

1

High-throughput

0.725

High

1027134

REEP5
Receptor expression-enhancing protein 5

4

14

High-throughput

0.699

High

1291458

RETR3
Reticulophagy regulator 3

3

7

High-throughput

0.665

High

1393452

SNX15
Sorting nexin-15

5

5

High-throughput

0.657

High

1111960

SNX1
Sorting nexin-1

5

4

High-throughput

0.656

High

140402

SDCB1
Syntenin-1

3

0

High-throughput

0.646

High

1393461

NDRG4
Protein NDRG4

3

0

High-throughput

0.645

High

728683

IL2RG
Cytokine receptor common subunit gamma

4

1

High-throughput

0.630

High

360076

NB5R3
NADH-cytochrome b5 reductase 3

2

2

High-throughput

0.614

High

1393431

REEP6
Receptor expression-enhancing protein 6

2

14

High-throughput

0.613

High

1366173

LPAR1
Lysophosphatidic acid receptor 1

3

6

High-throughput

0.609

High

1139245

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

2

3

High-throughput

0.606

High

1279350

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

4

High-throughput

0.606

High

1292861

STING
Stimulator of interferon genes protein

2

3

High-throughput

0.606

High

1393465

CERT
Ceramide transfer protein

2

2

High-throughput

0.606

High

669050

FPR2
N-formyl peptide receptor 2

3

6

High-throughput

0.604

High

1316348

AGRG5
Adhesion G-protein coupled receptor G5

3

1

High-throughput

0.604

High

1370206

CDS1
Phosphatidate cytidylyltransferase 1

2

0

High-throughput

0.602

High

1393459

KLRF1
Killer cell lectin-like receptor subfamily F member 1

3

6

High-throughput

0.599

High

849031

PTN9
Tyrosine-protein phosphatase non-receptor type 9

3

2

High-throughput

0.597

High

1392839

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

1393434

TLCD4
TLC domain-containing protein 4

2

0

High-throughput

0.580

High

252623

TSN2
Tetraspanin-2

2

9

High-throughput

0.574

High

733048

VIPR1
Vasoactive intestinal polypeptide receptor 1

2

4

High-throughput

0.574

High

949275

MYPR
Myelin proteolipid protein

2

1

High-throughput

0.574

High

1203333

TM128
Transmembrane protein 128

2

4

High-throughput

0.558

High

1338673

T185A
Transmembrane protein 185A

2

1

High-throughput

0.558

High

1393455

CLC5A
C-type lectin domain family 5 member A

2

3

High-throughput

0.558

High

329654

LERL1
Leptin receptor overlapping transcript-like 1

2

1

High-throughput

0.553

High

617572

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

2

1

High-throughput

0.553

High

870768

CXA8
Gap junction alpha-8 protein

2

1

High-throughput

0.553

High

1245838

TMED8
Protein TMED8

2

1

High-throughput

0.553

High

1254306

TMPPE
Transmembrane protein with metallophosphoesterase domain

2

2

High-throughput

0.553

High

1310920

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

2

High-throughput

0.553

High

1351681

GP152
Probable G-protein coupled receptor 152

2

9

High-throughput

0.553

High

1385356

MID49
Mitochondrial dynamics protein MID49

2

1

High-throughput

0.553

High

1393451

PICK1
PRKCA-binding protein

2

1

High-throughput

0.553

High

1393464

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

2

1

High-throughput

0.553

High

1393466

SNX11
Sorting nexin-11

2

4

High-throughput

0.553

High

1393467

SNX8
Sorting nexin-8

2

3

High-throughput

0.553

High

1393456

SL2A8
Solute carrier family 2, facilitated glucose transporter member 8

2

1

High-throughput

0.549

High

1238102

HMBX1
Homeobox-containing protein 1

1

0

High-throughput

0.549

High

1393446

GORS2
Golgi reassembly-stacking protein 2

1

2

High-throughput

0.541

High

180572

PLS1
Phospholipid scramblase 1

1

2

High-throughput

0.536

High

788512

DHB2
17-beta-hydroxysteroid dehydrogenase type 2

1

2

High-throughput

0.536

High

1053826

KDSR
3-ketodihydrosphingosine reductase

1

7

High-throughput

0.536

High

1083141

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

5

High-throughput

0.536

High

1349895

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

1

High-throughput

0.536

High

1358051

T170A
Transmembrane protein 170A

1

1

High-throughput

0.536

High

1393433

DIESL
DGAT1/2-independent enzyme synthesizing storage lipids

1

1

High-throughput

0.536

High

1393439

TMM43
Transmembrane protein 43

1

1

High-throughput

0.536

High

1393440

TM208
Transmembrane protein 208

1

3

High-throughput

0.536

High

1393441

EMC6
ER membrane protein complex subunit 6

1

1

High-throughput

0.536

High

1393448

SAYS1
SAYSvFN domain-containing protein 1

1

1

High-throughput

0.536

High

328976

RTN3
Reticulon-3

1

6

High-throughput

0.515

High

1393445

IPPK
Inositol-pentakisphosphate 2-kinase

1

0

High-throughput

0.513

High

1034045

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.493

High

1393447

MYG1
MYG1 exonuclease

1

0

High-throughput

0.493

High

326444

S1PR2
Sphingosine 1-phosphate receptor 2

1

5

High-throughput

0.489

High

349533

TSN15
Tetraspanin-15

1

6

High-throughput

0.489

High

477453

CD63
CD63 antigen

1

6

High-throughput

0.489

High

564848

NCAM1
Neural cell adhesion molecule 1

1

3

High-throughput

0.489

High

906334

GPC3
Glypican-3

1

1

High-throughput

0.489

High

956977

CXCR4
C-X-C chemokine receptor type 4

1

5

High-throughput

0.489

High

1031498

IFM3
Interferon-induced transmembrane protein 3

1

2

High-throughput

0.489

High

1092806

MALL
MAL-like protein

1

2

High-throughput

0.489

High

1160940

MOG
Myelin-oligodendrocyte glycoprotein

1

1

High-throughput

0.489

High

1200106

UNC50
Protein unc-50 homolog

1

1

High-throughput

0.489

High

1200369

KCP3
Keratinocyte-associated protein 3

1

1

High-throughput

0.489

High

1211187

ODR4
Protein odr-4 homolog

1

1

High-throughput

0.489

High

1286294

GALT7
N-acetylgalactosaminyltransferase 7

1

5

High-throughput

0.489

High

1312969

S35F2
Solute carrier family 35 member F2

1

4

High-throughput

0.489

High

1324334

SYS1
Protein SYS1 homolog

1

1

High-throughput

0.489

High

1329468

KTAP2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2

1

1

High-throughput

0.489

High

1331188

F241A
Uncharacterized protein FAM241A

1

1

High-throughput

0.489

High

1347191

LHPL5
LHFPL tetraspan subfamily member 5 protein

1

1

High-throughput

0.489

High

1386920

F241B
Protein FAM241B

1

2

High-throughput

0.489

High

1388156

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

4

High-throughput

0.489

High

1393432

F210B
Protein FAM210B, mitochondrial

1

1

High-throughput

0.489

High

1393453

KISHB
Protein kish-B

1

2

High-throughput

0.489

High

1393454

CT141
Uncharacterized protein C20orf141

1

1

High-throughput

0.489

High

1393457

GDE1
Glycerophosphodiester phosphodiesterase 1

1

1

High-throughput

0.489

High

1393460

PILRB
Paired immunoglobulin-like type 2 receptor beta

1

1

High-throughput

0.489

High

386097

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.481

High

990601

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

1004967

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

562312

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.470

High

1235088

Q6IQ43
Tyrosine-protein phosphatase non-receptor type 9

1

2

High-throughput

0.470

High

1393450

MID51
Mitochondrial dynamics protein MIEF1

1

1

High-throughput

0.470

High

1393462

SNX12
Sorting nexin-12

1

4

High-throughput

0.470

High

1393444

METL9
Protein-L-histidine N-pros-methyltransferase

1

1

High-throughput

0.445

High

1102443

BIK
Bcl-2-interacting killer

1

1

High-throughput

0.439

High

1255065

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

85148

B7Z3K1
cDNA FLJ51973

1

4

High-throughput

0.407

High

1195472

Q4KN05
KLRF1 protein

1

3

High-throughput

0.407

High

1341291

COQ8A
Atypical kinase COQ8A, mitochondrial

5

0

High-throughput

0.378

High

1393458

SPG21
Maspardin

4

0

High-throughput

0.364

High

1393436

THIOM
Thioredoxin, mitochondrial

3

0

High-throughput

0.352

High

1393438

ZFY21
Zinc finger FYVE domain-containing protein 21

3

0

High-throughput

0.352

High

1328726

FHI1B
FHF complex subunit HOOK-interacting protein 1B

2

0

High-throughput

0.337

High

139959

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

2

0

High-throughput

0.316

High

549858

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.316

High

883436

CY561
Transmembrane ascorbate-dependent reductase CYB561

2

0

High-throughput

0.316

High

1158475

CDC37
Hsp90 co-chaperone Cdc37

2

0

High-throughput

0.316

High

1165347

SYT16
Synaptotagmin-16

2

0

High-throughput

0.316

High

1348425

LNX1
E3 ubiquitin-protein ligase LNX

2

0

High-throughput

0.316

High

1383358

TM143
Transmembrane protein 143

2

0

High-throughput

0.316

High

1393443

KRA31
Keratin-associated protein 3-1

2

0

High-throughput

0.316

High

1224886

TENS2
Tensin-2

1

0

High-throughput

0.299

High

711582

NK3R
Neuromedin-K receptor

1

0

High-throughput

0.279

Low

845984

DCC
Netrin receptor DCC

1

0

High-throughput

0.279

Low

857156

NSF
Vesicle-fusing ATPase

1

0

High-throughput

0.279

Low

1219240

SYPL2
Synaptophysin-like protein 2

1

0

High-throughput

0.279

Low

1313680

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.279

Low

1393437

PRRT1
Proline-rich transmembrane protein 1

1

0

High-throughput

0.279

Low

1393442

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

441561

CCKN
Cholecystokinin

1

0

High-throughput

0.268

Low

1064005

ECHP
Peroxisomal bifunctional enzyme

1

0

High-throughput

0.268

Low

1393463

SHLB1
Endophilin-B1

1

0

High-throughput

0.268

Low

954226

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.251

Low

1109013

AQP6
Aquaporin-6

1

0

High-throughput

0.251

Low

1393449

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.251

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025