HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: KMT5C (Q86Y97)
Histone-lysine N-methyltransferase KMT5C (Lysine N-methyltransferase 5C) (Lysine-specific methyltransferase 5C) (Suppressor of variegation 4-20 homolog 2) (Su(var)4-20 homolog 2) (Suv4-20h2) ([histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B) (EC 2.1.1.362) ([histone H4]-lysine20 N-methyltransferase KMT5B) (EC 2.1.1.361)
Gene: KMT5C

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	24981860, 15145825, 19486527
Identification Methods	affinity chromatography technology, tandem affinity purification, pull down
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000779 - condensed chromosome, centromeric region GO:0000792 - heterochromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 1 others more... GO:0005721 - pericentric heterochromatin
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 462
+	Hs
		800449 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		KMT5C_HUMAN (1-462): 0: 790: 100.00
+	Hs
		949835 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		KMT5C_HUMAN (1-462): 0: 790: 100.00
+	Hs
		123278 CBX4_HUMAN (21-121): 4.95e-27: 108: 29.52		KMT5C_HUMAN (1-462): 0: 790: 100.00