HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: RSF1 (Q96T23)
Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex)
Gene: RSF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Chromo~PHD
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization GO:0006338 - chromatin remodeling GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 1441
+	Hs
		949866 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		RSF1_HUMAN (13-1441): 1.85e-171: 553: 100.00
+	Hs
		1027153 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ELYS_HUMAN (74-1393): 4.64e-49: 194: 9.68
+	Hs
		1027215 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		UHRF1_HUMAN (654-1274): 9.34e-39: 158: 13.05
+	Hs
		1027041 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		RIF1_HUMAN (177-1372): 1.34e-36: 154: 9.80
+	Hs
		1018451 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD3_HUMAN (475-1062): 1.62e-36: 153: 14.78
+	Mm
		1266178 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		TRI66_MOUSE (192-1090): 3.23e-35: 149: 10.17
+	Hs
		949854 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		ELYS_HUMAN (74-1393): 4.64e-49: 194: 9.68
+	Hs
		1027317 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		BAZ2A_HUMAN (404-1029): 4.52e-32: 139: 11.65
+	Hs
		782338 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		KDM5C_HUMAN (754-972): 3.88e-26: 119: 20.89
+	Hs
		1027145 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD5_HUMAN (827-1054): 1.31e-25: 117: 20.57
+	Hs
		800413 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		RIF1_HUMAN (177-1372): 1.34e-36: 154: 9.80
+	Hs
		800360 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		CHD3_HUMAN (475-1062): 1.62e-36: 153: 14.78
+	Mm
		1143042 CBX5_MOUSE (11-182): 1.21e-55: 175: 59.89		TRI66_MOUSE (192-1090): 3.23e-35: 149: 10.17
+	Hs
		949809 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		RIF1_HUMAN (177-1372): 1.34e-36: 154: 9.80
+	Hs
		949764 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		CHD3_HUMAN (475-1062): 1.62e-36: 153: 14.78
+	Hs
		1027001 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		CHD4_HUMAN (877-960): 3.83e-14: 80.1: 28.57
+	Mm
		1161080 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		CHD4_MOUSE (877-960): 5.99e-14: 79.7: 28.57
+	Hs
		800380 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		CHD4_HUMAN (877-960): 3.83e-14: 80.1: 28.57
+	Hs
		949784 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		CHD4_HUMAN (877-960): 3.83e-14: 80.1: 28.57
+	Mm
		949943 CBX1_MOUSE (36-180): 1.02e-53: 170: 71.33		CHD4_MOUSE (877-960): 5.99e-14: 79.7: 28.57